Pylephlebitis: Difference between revisions

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Pylephlebitis (also called infective suppurative thrombosis of the portal vein) is an uncommon inflammation of the portal vein or any of its branches. It is usually a complication of intraabdominal sepsis, most often following diverticulitis, perforated appendicitis, or peritonitis. Considered uniformly lethal in the pre-antibiotic era, it still carries a mortality of 10-30%. It typically presents with fever, rigors, and right upper quadrant abdominal pain, but sometimes abdominal pain may be absent. Liver function test abnormalities are usually present but frank jaundice is uncommon.

Once diagnosed the infection is treated by administering common antibiotics which will end the sepsis.

It is a cause of portal hypertension.

References

The American Journal of Gastroenterology 96, 1312–1313 (1 April 2001) | doi:10.1111/j.1572-0241.2001.03736.x

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-'''Pylephlebitis''' (also called '''infective suppurative thrombosis of the portal vein''') is an [[inflammation]] of the [[portal vein]] or any of its branches. It is usually a complication of intraabdominal sepsis, most often following [[diverticulitis]], perforated [[appendicitis]], or [[peritonitis]]. It has a poor prognosis. It typically presents with chill, fever, rigors, pain in the right hypochondria and jaundice but sometimes abdominal pain may be absent.  It is rather seldom.
+'''Pylephlebitis''' (also called '''infective suppurative thrombosis of the portal vein''') is an uncommon [[inflammation]] of the [[portal vein]] or any of its branches. It is usually a complication of intraabdominal sepsis, most often following [[diverticulitis]], perforated [[appendicitis]], or [[peritonitis]]. Considered uniformly lethal in the pre-antibiotic era, it still carries a mortality of 10-30%. It typically presents with fever, rigors, and right upper quadrant abdominal pain, but sometimes abdominal pain may be absent.  Liver function test abnormalities are usually present but frank jaundice is uncommon.
 Once diagnosed the infection is treated by administering common [[antibiotics]] which will end the [[sepsis]].