Longevity genes: Difference between revisions
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==See also== |
==See also== |
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* [[List of life extension related topics]] |
* [[List of life extension related topics]] |
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==External links== |
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*[http://www.sciam.com/article.cfm?chanID=sa006&articleID=000B73EB-3380-13F6-B38083414B7F0000 Scientific American Magazine (March 2006 Issue) Unlocking the Secrets of Longevity Genes] |
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Revision as of 17:00, 11 July 2006
Confirmed Longevity Genes From Model Animals
| Podospora | Saccharomyces | Caenorhabditis | Drosophila | Mouse |
| grisea | LAG1 | daf-2 | sod1 | Prop-1 |
| LAC1 | age-1/daf-23 | cat1 | p66shc | |
| RAS1 | daf-18 | mth | ||
| RAS2 | akt-1/akt-2 | |||
| PHB1 | daf-16 | |||
| PHB2 | daf-12 | |||
| CDC7 | ctl-1 | |||
| BUD1 | old-1 | |||
| RTG2 | spe-26 | |||
| RPD3 | clk-1 | |||
| HDA1 | mev-1 | |||
| SIR2 | ||||
| SIR4-42 | ||||
| UTH4 | ||||
| YGL023 | ||||
| SGS1 | ||||
| RAD52 | ||||
| FOB1 |
The major genetic model organisms used in aging research are the filamentous fungus ('Podospora anserina'), bakers' yeast ('Saccharomyces cerevisiae'), the soil roundworm ('Caenorhabditis elegans'), the fruit fly ('Drosophila melanogaster'), and the mouse ('Mus musculus').