Talk:Spinal and bulbar muscular atrophy

I am happy to see Kennedy's Disease added to Wikipedia. It is a relatively unknown disease that impacts many throughout the world. It is an X-linked disease and is passed from the mother to some of her children. There is currently no treatment or cure. The Kennedy's Disease Association (http://www.kennedysdisease.org/index.html) was created to educate others on this disease and help find a treatment or cure. The KDA has over 700 associates in their database of which most have KD.

I hope this discussion format provides another vehicle to express concerns, find out additional information about KD, and open more doors. —Preceding unsigned comment added by BruceG (talk • contribs)

Kennedy Disease Genetic track

When looking at the genetic path of the disease, I am confused as to how many generations the disease can be passed on. If a man inherits the disease from his carrier mother and has daughters, can that daughter be a carrier that is able to pass it on to her sons? I know of a family where three of four brothers have Kennedy disease. Will the three brothers be able to pass it on to their daughters. Will their sons be immune to the disease end the genetic line of the disease? If the one brother who did not get the disease could he have a carrier daughter and will his sons be free of the disease and the genetic path will end with that generation?216.51.168.209 (talk) 14:06, 19 October 2008 (UTC)

Disambiguation

I've no idea how, but would it be worth sticking in a disambiguation page so that SBMA doesn't redirect you straight to an article a municiple authority in the philippines? 91.106.5.93 (talk) 12:48, 16 October 2009 (UTC)

A search for Kennedy's syndrome redirects to this page, though the two are very different (Kennedy's syndrome is actually Foster-Kennedy syndrome, and has an entry of it's own) —Preceding unsigned comment added by Eldorrogev (talk • contribs) 09:48, 10 April 2010 (UTC)

Resolved. kashmiri (talk) 14:51, 20 December 2011 (UTC)

Kennedy's disease or spinal and bulbar muscular atrophy?

Both names are used in medical literature, withKennedy's disease sounding a bit more vernacular. A quick search of pubmed has returned: 537 results for spinal and bulbar muscular atrophy and 180 results for Kennedy's disease. A search of pubget has returned respectively 343 and 240 results.

Spinal and bulbar muscular atrophy can be thus considered the technical name of the disease.

Hence, I propose to rename this article to spinal and bulbar muscular atrophy, with a redirect set for Kennedy's disease.

kashmiri (talk) 14:45, 20 December 2011 (UTC)

I disagree. While it is not an urgent thing or in fact even material whether the "main article" is titled Kennedy's Disease or "spinal and bulbar muscular atrophy" / SBMA, there is a reason it has become known as Kennedy's disease. For those directly involved in the field -- including clinical neurologists, researchers and patients -- both names are used and it's either / or with no ambiguity at all. "Kennedy's disease" is instantly recognizable and very specific. We do not go to Wiki as a source of information on the disease. But for the typical pedestrian Wiki reader Kennedy's disease would be less ambiguous since there are other diseases, e.g., spinal muscle atrophy (a.k.a. SMA types 1-3) that are already confused with KD in the lay literature but are truly unrelated to KD/SBMA. It is called Kennedy disease because that is how it has become known, being named after WR Kennedy's initial reported clinical study, reported in 1993 [Kennedy, William R., Milton Alter and Joo Ho Sung. 1968. Progressive proximal spinal and bulbar muscular atrophy of late onset. Neurology 18: 671-680]. I also find it curious that the authors of this sort of very specific medical/technical article are debating on what the disease should be called. If you decide to change the name to SBMA it is technically correct. But you then must go through a long list of other wiki articles on medical conditions and change all to use the technical names. For example

- Parkinson’s disease “...in 1917, an English doctor, James Parkinson, published his essay reporting six case of paralysis agitans...”

- Hodgkins’s disease “...Hodgkin's lymphoma was first described in an 1832 report by Thomas Hodgkin ...”

- Amyotrophic lateral sclerosis (ALS), is NOT KNOWN as “Waller – Charcot disease” even though in 1850 ...English scientist Augustus Waller first described the appearance of shriveled nerve fibers and French doctor Jean-Martin Charcot first described ALS symptoms in autopsy patients in 1869. (Charcot) published a paper in 1874 describing the disease whose title is the first formal use of the term ALS (...(d)e la sclérose latérale amyotrophique - "Amyotrophic Lateral Sclerosis"). In the U.S. at least, the disease familiarly became known cause célèbre as “Lou Gehrig’s disease” when in 1939 baseball legend Lou Gehrig's famously retired from baseball in his July 4, 1939 speech to a packed Yankee stadium crowd, and died two years later.

- Charcot-Marie-Tooth disease “...is named after the physicians and researchers who initially described it, i.e. Jean-Martin Charcot (1825–1893), his pupil Pierre Marie (1853–1940) "...Sur une forme particulière d'atrophie musculaire progressive, souvent familiale débutant par les pieds et les jambes et atteignant plus tard les mains" [Revue médicale (Paris) 6: 97–138. 1886], and Howard Henry Tooth (1856–1925) ("The peroneal type of progressive muscular atrophy", dissertation, London, 1886.)

- Huntington’s disease “…The first thorough description of the disease was by George Huntington in 1872. Examining the combined medical history of several generations of a family exhibiting similar symptoms, he realized their conditions must be linked…”

- Guillain-Barré Syndrome “…(i)n 1916, Georges Guillain, Jean Alexandre Barré, and André Strohl diagnosed two soldiers with the illness and described the key diagnostic abnormality of increased spinal-fluid protein production, but normal cell count …”

- Creutzfeldt-Jakob Disease “The disease was first described by German neurologist Hans Gerhard Creutzfeldt in 1920 and shortly afterward by Alfons Maria Jakob…” and was thereafter referred to as Creutfeldt-Jakob disease.

Danleywolfe (talk) 18:02, 27 November 2014 (UTC)