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== Research ==
== Research ==


Gábor Vajta’s contribution in embryology includes authorship in 343 publications cited 8434 times<ref>[http://scholar.google.com.au/citations?user=1DedetsAAAAJ&hl=en "G Vajta publications and citations on Google Scholar”]</ref>. He was author or co-editor of five books and theses, and reviewer of journals including [[Human Reproduction]]; Reproductive Biomedicine Online<ref>[http://www.rbmojournal.com/ "Website of Reproductive Biomedicine Online (journal)"]</ref>; [[Reproduction (journal)|Reproduction]]; [[Biology of Reproduction]], Cryobiology<ref>[http://www.journals.elsevier.com/cryobiology/ "Website of Cryobiology (journal)"]</ref>; Reproduction, Nutrition, Development<ref>[http://rnd.edpsciences.org/ "Website of Reproduction, Nutrition, Development (journal)"]</ref>; [[Reproduction, Fertility and Development]]; Theriogenology<ref>[http://www.theriojournal.com/ "Website of Theriogenology (journal)"]</ref>; Animal Reproduction Science<ref>[http://www.journals.elsevier.com/animal-reproduction-science/ "Website of Animal Reproduction Science (journal)"]</ref>; Reproduction in Domestic Animals; and Cellular Reprogramming<ref>[http://www.liebertpub.com/overview/cellular-reprogramming/9/ "Website of Cellular Reprogramming (journal)"]</ref>.
Gábor Vajta’s contribution in embryology includes authorship in 343 publications cited 8434 times.<ref>[http://scholar.google.com.au/citations?user=1DedetsAAAAJ&hl=en "G Vajta publications and citations on Google Scholar”]</ref> He was author or co-editor of five books and theses, and reviewer of journals including [[Human Reproduction]]; Reproductive Biomedicine Online;<ref>[http://www.rbmojournal.com/ "Website of Reproductive Biomedicine Online (journal)"]</ref> [[Reproduction (journal)|Reproduction]]; [[Biology of Reproduction]], Cryobiology;<ref>[http://www.journals.elsevier.com/cryobiology/ "Website of Cryobiology (journal)"]</ref> Reproduction, Nutrition, Development;<ref>[http://rnd.edpsciences.org/ "Website of Reproduction, Nutrition, Development (journal)"]</ref> [[Reproduction, Fertility and Development]]; Theriogenology;<ref>[http://www.theriojournal.com/ "Website of Theriogenology (journal)"]</ref> Animal Reproduction Science;<ref>[http://www.journals.elsevier.com/animal-reproduction-science/ "Website of Animal Reproduction Science (journal)"]</ref> Reproduction in Domestic Animals; and Cellular Reprogramming.<ref>[http://www.liebertpub.com/overview/cellular-reprogramming/9/ "Website of Cellular Reprogramming (journal)"]</ref>


== Handmade Cloning ==
== Handmade Cloning ==


HMC<ref>[http://appft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PG01&s1=20090119787.PGNR.&OS=DN/20090119787&RS=DN/20090119787 "Cell Nuclear Transfer"] patent no. US20090119787</ref> is a radical technical modification of [[Somatic cell nuclear transfer]] of the original mammalian nuclear transfer technology established by [[Steen Willadsen|Willadsen]] and applied for somatic cells by [[Ian Wilmut|Wilmut]] and [[Keith Campbell (biologist)|Campbell]]. The technique does not require micromanipulators only a simple stereomicroscope and an inexpensive fusion machine. All work is done by hand, with simple handheld tools (blade and micropipette).The first cloned animals in Africa<ref>[http://www.embryoplus.com/news_cloning_futhi.html "Futi on Embryo Plus"]</ref><ref>[http://news.bbc.co.uk/2/hi/africa/3007043.stm "Futi on BBC”]</ref> and Scandinavia<ref>[http://www.agrsci.org/djf/engelske_nyheder/denmark_s_first_cloned_pigs_are_born/ "Danish piglets”]</ref> were both produced by HMC. [[Transgenic]] pigs as models for various human diseases were produced with putative genes responsible for [[Parkinson's disease|Parkinson's]] and [[Alzheimer's disease]], [[Psoriasis]], [[Arteriosclerosis]] and [[Diabetes mellitus]]. The technology promises a new possibility for automation of the somatic cell nuclear transfer procedure. The birth of the first transgenic piglets containing the Alzheimer gene (29 October 2006)<ref>{{cite doi|10.1007/s11248-009-9245-4}}</ref> was rewarded as the Most important Scientific Achievement in Denmark in 2007<ref>[http://ing.dk/artikel/verdens-forste-klonede-alzheimers-grise-fodt-i-danmark-80756 "Ingeniøren Magazine"] in Danish language</ref>.
HMC<ref>[http://appft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PG01&s1=20090119787.PGNR.&OS=DN/20090119787&RS=DN/20090119787 "Cell Nuclear Transfer"] patent no. US20090119787</ref> is a radical technical modification of [[Somatic cell nuclear transfer]] of the original mammalian nuclear transfer technology established by [[Steen Willadsen|Willadsen]] and applied for somatic cells by [[Ian Wilmut|Wilmut]] and [[Keith Campbell (biologist)|Campbell]]. The technique does not require micromanipulators only a simple stereomicroscope and an inexpensive fusion machine. All work is done by hand, with simple handheld tools (blade and micropipette).The first cloned animals in Africa<ref>[http://www.embryoplus.com/news_cloning_futhi.html "Futi on Embryo Plus"]</ref><ref>[http://news.bbc.co.uk/2/hi/africa/3007043.stm "Futi on BBC”]</ref> and Scandinavia<ref>[http://www.agrsci.org/djf/engelske_nyheder/denmark_s_first_cloned_pigs_are_born/ "Danish piglets”]</ref> were both produced by HMC. [[Transgenic]] pigs as models for various human diseases were produced with putative genes responsible for [[Parkinson's disease|Parkinson's]] and [[Alzheimer's disease]], [[Psoriasis]], [[Arteriosclerosis]] and [[Diabetes mellitus]]. The technology promises a new possibility for automation of the somatic cell nuclear transfer procedure. The birth of the first transgenic piglets containing the Alzheimer gene (29 October 2006)<ref>{{cite doi|10.1007/s11248-009-9245-4}}</ref> was rewarded as the Most important Scientific Achievement in Denmark in 2007.<ref>[http://ing.dk/artikel/verdens-forste-klonede-alzheimers-grise-fodt-i-danmark-80756 "Ingeniøren Magazine"] in Danish language</ref>


== Open Pulled Straw (OPS) vitrification ==
== Open Pulled Straw (OPS) vitrification ==


OPS<ref>[http://www.open-pulled-straw.com/ "Open Pulled Straw website"]</ref> is the first purpose-developed tool for mammalian embryo and [[oocyte]] vitrification that has resulted in many breakthroughs in human and animal [[cryobiology]] including the first baby born after vitrification of human oocytes<ref>{{cite doi|10.1093/humrep/14.12.3077}}</ref>, and the first cloned mammal born after cryopreservation of the reconstructed embryo<ref>{{cite doi|10.1071/RD03052}}</ref>. OPS is also regarded as the most appropriate carrier tool for vitrification of human embryonic stem cells (hESCs)<ref>{{cite doi|10.1093/humrep/16.10.2187}}</ref>.
OPS<ref>[http://www.open-pulled-straw.com/ "Open Pulled Straw website"]</ref> is the first purpose-developed tool for mammalian embryo and [[oocyte]] vitrification that has resulted in many breakthroughs in human and animal [[cryobiology]] including the first baby born after vitrification of human oocytes,<ref>{{cite doi|10.1093/humrep/14.12.3077}}</ref> and the first cloned mammal born after cryopreservation of the reconstructed embryo.<ref>{{cite doi|10.1071/RD03052}}</ref> OPS is also regarded as the most appropriate carrier tool for vitrification of human embryonic stem cells (hESCs).<ref>{{cite doi|10.1093/humrep/16.10.2187}}</ref>


== References ==
== References ==

Revision as of 00:37, 24 January 2015

Gábor Vajta
Born (1952-08-25) 25 August 1952 (age 72)
Vác, Hungary
NationalityAustralian, Hungarian
Known forHMC (Handmade Cloning)
Scientific career
FieldsEmbryologist
Websitewww.gaborvajta.com

Gábor Vajta, MD, PhD, DSc (born 25 August 1952) is a medical doctor, human pathologist and mammalian embryologist living in Cairns, Queensland, Australia. Gábor Vajta is a Honorary Professor of the BGI College, Shenzhen, China, and Adjuct Professor of the Central Queensland University, Rockhampton, Queensland, Australia. After an early career (university lecturer, PhD) in human pathology he turned to embryology in 1989 and obtained a Doctor of Science degree in Domestic Animal Embryology at the Royal Veterinary and Agricultural University in Copenhagen, Denmark in 1999. During the past 25 years he has developed several patents relating to embryology, most notably the method of Handmade Cloning (HMC)[1], the Submarine Incubation System (SIS)[2], the Open Pulled Straw (OPS)[3] vitrification and the Well of the Well (WOW)[4] system. Currently Professor Vajta is director of a consulting company providing services in human and domestic animal embryology all over the world.

Research

Gábor Vajta’s contribution in embryology includes authorship in 343 publications cited 8434 times.[5] He was author or co-editor of five books and theses, and reviewer of journals including Human Reproduction; Reproductive Biomedicine Online;[6] Reproduction; Biology of Reproduction, Cryobiology;[7] Reproduction, Nutrition, Development;[8] Reproduction, Fertility and Development; Theriogenology;[9] Animal Reproduction Science;[10] Reproduction in Domestic Animals; and Cellular Reprogramming.[11]

Handmade Cloning

HMC[12] is a radical technical modification of Somatic cell nuclear transfer of the original mammalian nuclear transfer technology established by Willadsen and applied for somatic cells by Wilmut and Campbell. The technique does not require micromanipulators only a simple stereomicroscope and an inexpensive fusion machine. All work is done by hand, with simple handheld tools (blade and micropipette).The first cloned animals in Africa[13][14] and Scandinavia[15] were both produced by HMC. Transgenic pigs as models for various human diseases were produced with putative genes responsible for Parkinson's and Alzheimer's disease, Psoriasis, Arteriosclerosis and Diabetes mellitus. The technology promises a new possibility for automation of the somatic cell nuclear transfer procedure. The birth of the first transgenic piglets containing the Alzheimer gene (29 October 2006)[16] was rewarded as the Most important Scientific Achievement in Denmark in 2007.[17]

Open Pulled Straw (OPS) vitrification

OPS[18] is the first purpose-developed tool for mammalian embryo and oocyte vitrification that has resulted in many breakthroughs in human and animal cryobiology including the first baby born after vitrification of human oocytes,[19] and the first cloned mammal born after cryopreservation of the reconstructed embryo.[20] OPS is also regarded as the most appropriate carrier tool for vitrification of human embryonic stem cells (hESCs).[21]

References

  1. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1089/15204550152475590, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi=10.1089/15204550152475590 instead.
  2. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1016/S0093-691X(97)00379-8, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi=10.1016/S0093-691X(97)00379-8 instead.
  3. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1002/(SICI)1098-2795(199809)51:1<53::AID-MRD6>3.0.CO;2-V, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi=10.1002/(SICI)1098-2795(199809)51:1<53::AID-MRD6>3.0.CO;2-V instead.
  4. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1002/(SICI)1098-2795(200003)55:3<256::AID-MRD3>3.0.CO;2-7, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi=10.1002/(SICI)1098-2795(200003)55:3<256::AID-MRD3>3.0.CO;2-7 instead.
  5. ^ "G Vajta publications and citations on Google Scholar”
  6. ^ "Website of Reproductive Biomedicine Online (journal)"
  7. ^ "Website of Cryobiology (journal)"
  8. ^ "Website of Reproduction, Nutrition, Development (journal)"
  9. ^ "Website of Theriogenology (journal)"
  10. ^ "Website of Animal Reproduction Science (journal)"
  11. ^ "Website of Cellular Reprogramming (journal)"
  12. ^ "Cell Nuclear Transfer" patent no. US20090119787
  13. ^ "Futi on Embryo Plus"
  14. ^ "Futi on BBC”
  15. ^ "Danish piglets”
  16. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1007/s11248-009-9245-4, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi=10.1007/s11248-009-9245-4 instead.
  17. ^ "Ingeniøren Magazine" in Danish language
  18. ^ "Open Pulled Straw website"
  19. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1093/humrep/14.12.3077, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi=10.1093/humrep/14.12.3077 instead.
  20. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1071/RD03052, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi=10.1071/RD03052 instead.
  21. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1093/humrep/16.10.2187, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi=10.1093/humrep/16.10.2187 instead.

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