Epitestosterone: Difference between revisions
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Epitestosterone is a natural [[steroid]], chemically similar to [[testosterone]]. Epitestosterone is believed to form in a similar way to testosterone, however, the exact site of its formation is unknown. Furthermore, exogenous administration of testosterone does not affect levels of epistestosterone in the body. |
Epitestosterone is a natural [[steroid]], chemically similar to [[testosterone]]. Epitestosterone is believed to form in a similar way to testosterone, however, the exact site of its formation is unknown. Furthermore, exogenous administration of testosterone does not affect levels of epistestosterone in the body. |
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As a result, tests to determine the ratio of testosterone to epitestosterone in urine are used to find athletes who are [[Doping (Sport)|doping]]. A normal healthy person has a ratio of about 1:1 testosterone to epitestosterone in their urine<ref>{{cite news | url=http://www.asada.gov.au/substances/facts/testosterone.htm | title=Substances: Testosterone to epitestosterone (T/E) ratio | publisher=Australian Government | date=Tuesday, February 28, 2006}}</ref>. |
As a result, tests to determine the ratio of testosterone to epitestosterone in urine are used to find athletes who are [[Doping (Sport)|doping]]. A normal healthy person has a ratio of about 1:1 testosterone to epitestosterone (T/E ratio) in their urine<ref>{{cite news | url=http://www.asada.gov.au/substances/facts/testosterone.htm | title=Substances: Testosterone to epitestosterone (T/E) ratio | publisher=Australian Government | date=Tuesday, February 28, 2006}}</ref>. |
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Although epitestosterone has not been shown to enhance athletic performance, administration of epistestosterone can be used to mask a high level of testosterone if the standard T/E ratio test is used. As such, epitestosterone is banned by many sporting authorities as a masking agent for testosterone. |
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It was revealed on [[July 27]], [[2006]] that [[Floyd Landis]], winner of the [[2006 Tour de France]], had a testosterone to epitestosterone ratio of 11:1 {{fact}}, in violation of the 4:1 limit imposed by the race organizers, suggesting doping, though this may have been caused by a low epitestosterone level rather than an artificially elevated testosterone level. Landis has also claimed that an elevated testosterone level could be related to his [[hypothyroidism]]. |
It was revealed on [[July 27]], [[2006]] that [[Floyd Landis]], winner of the [[2006 Tour de France]], had a testosterone to epitestosterone ratio of 11:1 {{fact}}, in violation of the 4:1 limit imposed by the race organizers, suggesting doping, though this may have been caused by a low epitestosterone level rather than an artificially elevated testosterone level. Landis has also claimed that an elevated testosterone level could be related to his [[hypothyroidism]]. |
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Revision as of 08:43, 30 July 2006
| Identifiers | |
|---|---|
| |
| CAS Number | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.169.813 |
| Chemical and physical data | |
| Formula | C19H28O2 |
| Molar mass | 288.42 |
Epitestosterone is a natural steroid, chemically similar to testosterone. Epitestosterone is believed to form in a similar way to testosterone, however, the exact site of its formation is unknown. Furthermore, exogenous administration of testosterone does not affect levels of epistestosterone in the body.
As a result, tests to determine the ratio of testosterone to epitestosterone in urine are used to find athletes who are doping. A normal healthy person has a ratio of about 1:1 testosterone to epitestosterone (T/E ratio) in their urine[1].
Although epitestosterone has not been shown to enhance athletic performance, administration of epistestosterone can be used to mask a high level of testosterone if the standard T/E ratio test is used. As such, epitestosterone is banned by many sporting authorities as a masking agent for testosterone.
It was revealed on July 27, 2006 that Floyd Landis, winner of the 2006 Tour de France, had a testosterone to epitestosterone ratio of 11:1 [citation needed], in violation of the 4:1 limit imposed by the race organizers, suggesting doping, though this may have been caused by a low epitestosterone level rather than an artificially elevated testosterone level. Landis has also claimed that an elevated testosterone level could be related to his hypothyroidism.
External links
Landis Fails Drug Test After Triumph in Tour de France
Institute of Endocrinology Abstract on Epistestosterone
Notes
- ^ "Substances: Testosterone to epitestosterone (T/E) ratio". Australian Government. Tuesday, February 28, 2006.
{{cite news}}: Check date values in:|date=(help)