Astellas Pharma: Difference between revisions
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===Products=== |
===Products=== |
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Some of the key products produced by Astellas include: |
Some of the key products produced by Astellas include: |
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* |
*Prograf ([[tacrolimus]]) - Prevention of post-[[organ transplantation|transplant]] [[organ rejection]] |
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*Protopic ([[tacrolimus]] ointment) - Atopic dermatitis ([[eczema]]) |
*Protopic ([[tacrolimus]] ointment) - Atopic dermatitis ([[eczema]]) |
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*Amevive ([[alefacept]]) - Plaque [[psoriasis]] |
*Amevive ([[alefacept]]) - Plaque [[psoriasis]] |
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Revision as of 00:46, 1 July 2015
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| Company type | Public KK |
|---|---|
| Industry | Pharmaceutical |
| Predecessors | Yamanouchi Pharmaceutical Fujisawa Pharmaceutical (Merged in 2005) |
| Founded | 2005 |
| Headquarters | 2-5-1, Nihonbashi-Honcho, Chūō-ku, Tokyo 103-8411, Japan |
Key people | Yoshihiko Hatanaka (President and CEO) |
| Products |
|
| Revenue |  US$11,060,000,000 (FY 2013) |
| US$1,280,000,000 (¥1,139,000,000,000) (FY 2013) | |
Number of employees | 17,649 (consolidated as of March 2014) |
| Subsidiaries | Astellas US |
| Website | Official website |
| Footnotes / references [1][2][3] | |
Astellas Pharma Inc. (アステラス製薬株式会社, Asuterasu Seiyaku Kabushiki-gaisha) is a Japanese pharmaceutical company, formed on 1 April 2005 from the merger of Yamanouchi Pharmaceutical Co., Ltd. (山之内製薬株式会社, Yamanouchi Seiyaku Kabushiki-gaisha) and Fujisawa Pharmaceutical Co., Ltd. (藤沢薬品工業株式会社, Fujisawa Yakuhin Kōgyō Kabushiki-gaisha).
History
Fujisawa Shoten was started in 1894 by Tomokichi Fujisawa in Osaka, and was renamed Fujisawa Pharmaceutical Co. in 1943.
Yamanouchi Yakuhin Shokai was started in 1923 by Kenji Yamanouchi in Osaka. The company was renamed Yamanouchi Pharmaceutical Co. in 1940 and moved to Tokyo in 1942.
Both companies started their overseas expansion at about the same time, opening offices in Taiwan in 1962 and 1963, respectively, and in the United States and Europe from 1977 onwards. Fujisawa acquired Lyphomed in 1990 and thereafter established its US R&D center in Deerfield, Illinois. Yamanouchi's R&D center in Leiderdorp was established with the acquisition of the pharmaceutical division of Royal Gist Brocades in 1991.
Fujisawa and Yamanouchi combined in a "merger of equals," forming Astellas Pharma on 1 April 2005.
At least some of its older products continue to be distributed under the original brand, ostensibly due to high brand-name recognition.[4]
Astellas had a collaboration agreement with CoMentis from 2008 to 2014 focused on development of beta-secretase inhibitor therapeutics for Alzheimer's disease.[5]
On June 9, 2010, Astellas acquired OSI Pharmaceuticals for $4.0 billion.
In December 2014, Astellas expanded its 18-month-old collaboration with Cytokinetics, focussing on the R&D and commercialisation of skeletal muscle activators. The companies announced they will advance the development of CK-2127107 (a fast skeletal troponin activator) into Phase II clinical trials for the treatment of Spinal Muscular Atrophy and possibly other neuromuscular conditions. The companies have extended their R&D program focussing on the discovery of additional skeletal sarcomere activators through into 2016. The collaboration is expected to generate more than $600 million for Cytokinetics as well as $75 million in milestone payments.[6]
Business
Astellas' franchise areas are urology, immunology (transplantation), dermatology, cardiology, and infectious disease. Priority areas for R&D are infectious diseases, diabetes, gastrointestinal diseases, oncology, and diseases of the central nervous system.
Products
Some of the key products produced by Astellas include:
- Prograf (tacrolimus) - Prevention of post-transplant organ rejection
- Protopic (tacrolimus ointment) - Atopic dermatitis (eczema)
- Amevive (alefacept) - Plaque psoriasis
- VESIcare (solifenacin succinate) - Overactive bladder (OAB) marketed with GlaxoSmithKline
- Myrbetriq (mirabegron) - Overactive bladder (OAB) US only marketed by Pfizer Outside of US
- Flomax (tamsulosin hydrochloride) - Benign prostatic hyperplasia (BPH)
- Adenocard (adenosine injection) - Pharmacologic stress agent for myocardial perfusion scan
- Adenoscan (adenosine injection) - Pharmacologic stress agent for myocardial perfusion scan
- Lexiscan (regadenoson injection) - Pharmacologic stress agent for myocardial perfusion scan
- Vaprisol (conivaptan) - Hyponatremia
- AmBisome (amphotericin B) - Anti-fungal
- Mycamine (micafungin sodium) - Anti-fungal
- Symoron (methadone HCL) - narcotics misuse cessation
- Tarceva (erlotinib) - Non-small cell lung cancer and pancreatic cancer
- Xtandi (enzalutamide) - Prostate cancer
Operations
The company's headquarters are in Tokyo, with research centers in Tsukuba and Osaka. Clinical development is centered in Northbrook, Illinois and Leiden, Netherlands. Combined revenues of the two pre-merger companies were $7.9 billion in 2004. Worldwide the company employs about 17,000 people. The United States subsidiary of Astellas is Astellas US LLC.[7]
The company's advertising slogans are:
- English: Leading Light for Life
- Japanese: Ashita wa kaerareru. (明日は変えられる。, Changing Tomorrow.)[8]
References
- ^ "Corporate Profile". Astellas Pharma. Retrieved September 9, 2014.
- ^ "Annual Report 2014" (PDF). Astellas Pharma. Retrieved September 9, 2014.
- ^ "Astellas Pharma Snapshot". Bloomberg Businessweek. Retrieved January 25, 2015.
- ^ "Yamanouchi Pimafucin (natamycin) product line manufactured at least up to 11/2007"
- ^ Staff (November 15, 2014). "Astellas Ends Alzehimer's Collaboration with CoMentis". Discovery & Development. Gen. Eng. Biotechnol. News (paper). Vol. 34, no. 20. p. 14.
- ^ http://www.genengnews.com/gen-news-highlights/astellas-cytokinetics-expand-muscle-drug-collaboration/81250735/
- ^ Slatko, Joshua (December 2013). "BMS changes senior management team". People on the Move: Pharma. Med Ad News. p. 27.
- ^ "Corporate Philosophy of Astellas Pharma". Astellas Pharma. Retrieved September 9, 2014.
External links
