Talk:Hyperthyroidism

Untitled

Should treatment discussion be on pages more specific to complaint?

Whilst most hyperthyroidism is easily treated, there are conditions that cause hyperthyroidism that are less easy to treat. Or as the advice one thyroid charity gives its telephone advisers 'avoid saying "it'll be alright" as sometimes it isn't'.

Radioiodine and Surgery treatment

The text concerning the above comes in part from MediPrimer:Hyperthyroidism. As the copyright holder of that website, I authorize the use of this text under the GFDL as part of Wikipedia. Yashka78 00:11, 23 Jun 2005 (UTC) Well, I regard, te article must explain about the preparation step by step that wich th patients must take when are treat, for example, they need to remain in dark place, singles, without other persons,because the drog is radiactive.

In animals

Surgery is an option in feline hyperthyroidism, although it carries with it a number of risks. Radioiodine treatment is usually curative, while medication with methimazole may be used to control symptoms. All of these treatment options have advantages and disadvantages, so it is important to consider these and discuss them with a veterinarian.

"hyperthoxemia"?

What does this word mean? It's in the opening paragraph, but it doesn't google out. Google suggests "hyperthyroxemia", but that's not much better, with only 60 hits on google. Pubmed didn't have any hits for either, but suggested "hyperoxemia" for the first word and "hyperthyroxinemia" for the second one. If somebody knows what the author was going for, please fix it, but otherwise we might need to take the sentence out.--Arcadian 01:56, 30 November 2005 (UTC)

• hyperthyroxinemia - fixed. --Hugh2414 09:34, 30 November 2005 (UTC)
  • Thanks for the quick response and fix. --Arcadian 15:49, 30 November 2005 (UTC)

Other symptoms

Gynaecomastia and feminization as hypertiroidism symptoms. Just added some extra info, as they are quite prevalent. Will continue to edit the article with up to date info. — Preceding unsigned comment added by Aleyte (talk • contribs) 00:39, 26 February 2011 (UTC)

Sorry. It may just be me, but isn't eye bulging a sign of hyperthroidism?

No, not necessarily. It may occur in Graves' disease, a common (but not the only) cause of hyperthyroidism. Isolated toxic nodules and a toxic nodular struma are not typically characterised by eye bulging. The eye bulging is due to the presence of TSH receptors on the retraorbital musculature, which are stimulated by the antibody. JFW | T@lk 21:54, 30 April 2006 (UTC)

T3 & T4

I noticed the article says hyperthyroidism can be caused by an excess or either T3 or T4 or both. Are the symptoms any different depending on which? 69.85.180.128 11:04, 3 February 2007 (UTC)

No, unless they are being caused by overose on pills. Then the T3 symptoms go away faster when the pills are stopped, due to its shorter half-life. SBHarris 15:15, 3 February 2007 (UTC)

Natural treatments?

Does anyone know of any supposed natural treatments, like with herbs or exercises? --Remi0o 03:27, 24 March 2007 (UTC)

Unlikely - the FDA would put a stop to that quickly... [[TheAngriestPharmacist]] 09:30, 3 May 2007 (UTC)

Under the Food and Diet section, something about the effect of goitrogenic foods such as cabbage, cauliflower etc, which are members of the Brassica family, on hyperthyroidism may be mentioned. A diet high in such foods may show an anti thyroid effect, though using this alone is not advisable, and must be done in conjunction with proper medication and treatment. One reference in this regard is Chandra, Amar K et al, Indian J Med Res 119, May 2004, pp 180-185.nimswrit (talk) 17:32, 29 October 2013 (UTC)

Thyroid Storm Treatment

• Propylthiouracil 900–1200 mg/day orally in four or six divided doses
• Methimazole 90–120 mg/day orally in four or six divided doses

• Sodium iodide Up to 2 g/day IV in single or divided doses
• Lugol’s solution 5–10 drops three times a day in water or juice
• Saturated solution of KI 1–2 drops three times a day in water or juice

• Propranolol 40–80 mg every 6 h

• Dexamethasone 5–20 mg/day orally or IV in divided doses
• Prednisone 25–100 mg/day orally in divided doses
• Methylprednisolone 20–80 mg/day IV in divided doses
• Hydrocortisone 100–400 mg/day IV in divided doses

[[TheAngriestPharmacist]] 09:29, 3 May 2007 (UTC)

2 issues - firstly, you should mention that the iodine based compounds ought to be given 1 to 4 hours after propylthiouracil (PTU). PTU is also the drug of choice for storm because of its effect on reducing T4 to T3 conversion. secondly i note that the main article states that TSH is the marker used in detecting hyperthyroidism - however there are certain conditions in which TSH is elevated (e.g. TSHoma) or unreliable (e.g. pregnancy) -- Unsigned

Sometimes though, TSH is all that can be used in detecting underlying thyroid issues as is

the case in subclinical hyper(or hypo)thyroidism. [[TheAngriestPharmacist]] 03:49, 6 May 2007 (UTC)

Hashimoto's Thyroiditis

Hashimoto's Thyroiditis is listed as the forth major cause of hyperthyroidism in this article but looking at the Hashimoto's article that it links to it is clear that it is a cause of HYPO thyroidism as it is a result of the autoimmune system attacking the thyroid gland.

Would someone care to clarify/fix/comment on this issue? Sail.not.swim (talk) 23:53, 18 November 2007 (UTC)

Hashimoto's thyroiditis is autoimmune inflamation and destruction of the thyroid gland as opposed to graves disease, in which auto antibodys mimick TSH to stimulate the thyroid.

In hashimoto's the initial inflamation of the gland causes release of T₃ and T₄ leaving the person transiently hyperthroid which is often sub clinical. As more and more and more of the gland is inflamed, damaged and destroyed its capability to produce T₃ and T₄ is compromised and the transient hyperthyroidism gives way to hypothyroidism, the more common clinical presentation of hashimoto's. —Preceding unsigned comment added by 80.235.131.226 (talk) 20:44, 1 April 2008 (UTC)

PBDEs & hyperthryoidism in cats

This subject has been given undue prominence - the 2007 article which proposed a link between PBDE and hyperthyroidism in cats ([1]) showed that the level of PBDEs in cats with hyperthyroidism was not significantly higher than the levels in other groups of cats, giving no evidence that PBDEs were responsible for the increase in hyperthyroidism in pet cats. A good discussion of the original Dye article was printed in the letters to the Veterinary Record: (letter from Kerry Simpson and the Feline Advisory Bureau feline expert panel [2])

Alternative suggested causes of the increased incidence of feline hyperthyroidism have been proposed over time - I would suggest these should be included in any discussion, although nothing has been proven to be a cause, otherwise hyperthyroidism in cats would be preventable... Murphyetta (talk) 14:05, 16 March 2008 (UTC)

Tiredness

Alot of well-meaning websites and people say that only hypothroidism causes symptoms of tiredness. However, I would like to bring it to people's attention that a hyperactive thyroid also causes tiredness... usually after anxiety symptoms or hyperactivity symptoms but still it can cause severe tiredness and an inability to experience pleasure (anhedonia. —Preceding unsigned comment added by Interestedperson (talk • contribs) 12:19, 23 November 2008 (UTC)

Radioiodine treatment for cats - biased?

The section on radioiodine treatment of cats reads as though it is only available in the US as it talks of quarantine periods varying from state to state. It would be more of a world view to say "from country to country, and even from place to place within one country"

It also makes two statements about surgery, that the other gland can become hyper after surgery and that the patient can become hypothyroid after surgery, but both of these are true of I-131 treatment as well.

PurplePenny (talk) 20:51, 5 September 2009 (UTC)

Varying Etiology of Thyrotoxicosis as Graves Disease with location

Hi, I think it should be mentioned that, although in the article it says that Graves disease is the cause of thyrotoxicosis 70-80% of the time (and this may be the world average, I don't know), actually it substantially varies with location. In the USA, 93% (toxic nodules - 5%, other 2%); the European average, 60% (toxic nodules 9%, other 31%); Switzerland, 43% (toxic nodules 57%). I'm a medical student and this was in my lecture notes. Therefore, I'm certain it would be right but also I can't find a reference for it. I have asked my lecturer so will find out why this happens (as genetics and environment seem too similar to warrant such a difference) —Preceding unsigned comment added by 159.92.101.51 (talk) 23:02, 14 April 2010 (UTC)

nice, hope you can get the reference Starvee44 (talk) 10:03, 15 April 2010 (UTC)

Reference 6 which refers to Graves' disease is an inactive link(gives error 404 - Not found).nimswrit (talk) 08:38, 28 October 2013 (UTC)

Thyroid storm dating

Query: Should 'Earlier this century' be 'until the late 20th century'?--Robert EA Harvey (talk) 07:30, 10 July 2011 (UTC)

The reference (and the reference it referred to) says 20th. I made it clear and removed the notation. MartinezMD (talk) 19:17, 10 March 2012 (UTC)

A nice 2012 Lancet review

[3] --Doc James (talk · contribs · email) 08:31, 25 March 2012 (UTC)

Separate human and nonhuman animals

Would it be wise to separate out the section on humans from the material on nonhumans? It seems to me that it would keep each page clear and to the point. For example, if I visit "Food" I don't get bombarded with info about food for cats, dogs, etc...just generally for humans. Gautam ^Discuss 22:53, 7 May 2012 (UTC)

Yeah, the vet stuff should probably be a completely separate article. We should have a hyperthyroidism (medicine) and a hyperthyroidism (veterinary medicine). SBHarris 23:51, 7 May 2012 (UTC)

copyvio removal

== Copyright problem removed ==

Prior content in this article duplicated one or more previously published sources. The material was copied from: http://www.thyroid.org/what-is-hyperthyroidism. Copied or closely paraphrased material has been rewritten or removed and must not be restored, unless it is duly released under a compatible license. (For more information, please see "using copyrighted works from others" if you are not the copyright holder of this material, or "donating copyrighted materials" if you are.) For legal reasons, we cannot accept copyrighted text or images borrowed from other web sites or published material; such additions will be deleted. Contributors may use copyrighted publications as a source of information, but not as a source of sentences or phrases. Accordingly, the material may be rewritten, but only if it does not infringe on the copyright of the original or plagiarize from that source. Please see our guideline on non-free text for how to properly implement limited quotations of copyrighted text. Wikipedia takes copyright violations very seriously, and persistent violators will be blocked from editing. While we appreciate contributions, we must require all contributors to understand and comply with these policies. Thank you. 67.162.112.133 (talk) 02:27, 2 September 2012 (UTC)

Hyperthyroidism usually begins slowly....causes other problems.

That entire paragraph was a straight lift from their website, which is straight copyright-protected.

Causes

Toxic Thyroid Adenoma has "(the most common etiology in Switzerland, 53%, thought to be atypical due to a low level of dietary iodine in this country)" next to it - however it seems that the iodine deficiency is a cause of multinodular goitre from other sources. Can any medics or even card carrying endocrinologists confirm this?

Sleevicus (talk) 20:55, 27 April 2013 (UTC)

Hypothyroidism

Hyperthyroidism due to certain types of thyroiditis can eventually lead to hypothyroidism (a lack of thyroid hormone), as the thyroid gland is damaged. Also, radioiodine treatment of Graves' disease often eventually leads to hypothyroidism. Such hypothyroidism may be avoided by regular thyroid hormone testing and oral thyroid hormone supplementation. -- references needed, and 'avoided' should be replaced by 'treated'.nimswrit (talk) 07:12, 28 October 2013 (UTC)

s/avoided/treated/ makes sense, just do it. The statements otherwise seem obvious so references are only needed if contested. Richiez (talk) 13:08, 29 October 2013 (UTC)

Guideline

doi:10.1089/thy.2010.0417 is the ATA/AACE guideline for hyperthyroidism. Worth including.

This is the UK guideline, now 7 years old and in need of updating and formatting. JFW | T@lk 20:09, 26 December 2013 (UTC)

Diagnostic criteria based on clinical signs

has anybody ever heard of the Burch-Wartofsky score? shouldn't this be included? http://flexikon.doccheck.com/en/Burch-Wartofsky-Score