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An upper respiratory tract illness characterized by sore throat, low-grade fever, and an adherent membrane of the tonsil(s), pharynx, and/or nose. A more milder form of diptheria can also effect the skin.
An upper respiratory tract illness characterized by sore throat, low-grade fever, and an adherent membrane of the tonsil(s), pharynx, and/or nose. A more milder form of diptheria can also effect the skin.
Diptheria is a contagious disease spread by direct physical contact or breathing the secretions of those infected. In 19th century, it was one of the most dreaded of childhood diseases, perhaps killing as much as 10% of those who contracted it. Now largely eradicated in developed nations, the vaccine DPT (Diptheria-Tetanus-Polio) is given to all school children. Boosters of the vaccine though is recommended to adults, as effects of the vaccine decrease as one gets older.
Diptheria is a contagious disease spread by direct physical contact or breathing the secretions of those infected. Diphtheria was one of the most dreaded of childhood diseases, perhaps killing as much as 10% of those who contracted it. Now largely eradicated in developed nations, there fewer than 5 cases a year reported in the United States since 1980. The vaccine DPT (Diptheria-Tetanus-Polio) is given to all school children. Boosters of the vaccine though is recommended to adults, as effects of the vaccine decrease as one gets older, especially travelling abroad to third-world nations.


Diptheria (dif-thir-ee-uh or often dip-thir-ee-uh) takes its name from the Greek word for "leather", ''dipthera'' and was named in 1855 by French physician A. Trousseau. This coinage alludes to the leathery, sheath-like membrane that grows on the tonsils, throat and in the nose.
Diptheria (dif-thir-ee-uh or often dip-thir-ee-uh) takes its name from the Greek word for "leather", ''dipthera'' and was named in 1855 by French physician A. Trousseau. This coinage alludes to the leathery, sheath-like membrane that grows on the tonsils, throat and in the nose.
The respitory form has an incubation of 1-4 days. Symptoms include a fatigue, a fever, a mild sore throat, problems swallowing. Children infected have symptoms that include nausea, vomiting, chills, and a high fever, although some do not show symptoms until the infection has progressed more.
The respitory form has an incubation of 1-4 days. Symptoms include a fatigue, a fever, a mild sore throat,
problems swallowing. Children infected have symptoms that include nausea, vomiting, chills, and a high fever, although some do not show symptoms until the infection has progressed more.


The disease may remain manageable, but in more severe cases lymph nodes in neck may swell, and breathing and swallowing will be more difficult. People in this stage should seek immediate medical attention, as obstruction in throat may require a tracheostomy. In addition, the increase in heart rate may cause cardiac arrest. Patients with severe cases will be put in ICU's (Intensive Care Units) at hospitals and be given a diptheria anti-toxin and bacterial killing drugs penicillin and erythromycin. Bed rest is important and physcial activity should be limited, especially in cases where there is inflammation of the heart muscles.
The disease may remain manageable, but in more severe cases lymph nodes in neck may swell, and breathing and swallowing will be more difficult. People in this stage should seek immediate medical attention, as obstruction in throat may require a tracheostomy. In addition, the increase in heart rate may cause cardiac arrest. Patients with severe cases will be put in ICU's (Intensive Care Units) at hospitals and be given a diptheria anti-toxin and bacterial killing drugs penicillin and erythromycin. Bed rest is important and physcial activity should be limited, especially in cases where there is inflammation of the heart muscles. Recovery is generally slow.
Diphtheria is considered



Revision as of 22:40, 19 October 2004

The clinical case definition of diphtheria is:

An upper respiratory tract illness characterized by sore throat, low-grade fever, and an adherent membrane of the tonsil(s), pharynx, and/or nose. A more milder form of diptheria can also effect the skin.

 Diptheria is a contagious disease spread by direct physical contact or breathing the secretions of those infected.  Diphtheria was one of the most dreaded of childhood diseases, perhaps killing as much as 10% of those who contracted it.  Now largely eradicated in developed nations, there fewer than 5 cases a year reported in the United States since 1980.  The vaccine DPT (Diptheria-Tetanus-Polio) is given to all school children.  Boosters of the vaccine though is recommended to adults, as effects of the vaccine decrease as one gets older, especially travelling abroad to third-world nations.    
 Diptheria (dif-thir-ee-uh or often dip-thir-ee-uh) takes its name from the Greek word for "leather", dipthera and was named in 1855 by French physician A. Trousseau.  This coinage alludes to the leathery, sheath-like membrane that grows on the tonsils, throat and in the nose.  
 
 The respitory form has an incubation of 1-4 days.  Symptoms include a fatigue, a fever, a mild sore throat, 

problems swallowing. Children infected have symptoms that include nausea, vomiting, chills, and a high fever, although some do not show symptoms until the infection has progressed more.

 The disease may remain manageable, but in more severe cases lymph nodes in neck may swell, and breathing and swallowing will be more difficult.  People in this stage should seek immediate medical attention, as obstruction in throat may require a tracheostomy.  In addition, the increase in heart rate may cause cardiac arrest.  Patients with severe cases will be put in ICU's (Intensive Care Units) at hospitals and be given a diptheria anti-toxin and bacterial killing drugs penicillin and erythromycin.  Bed rest is important and physcial activity should be limited, especially in cases where there is inflammation of the heart muscles.  Recovery is generally slow.  
  Diphtheria is considered 
 

Laboratory criteria for diagnosis:

  • Isolation of Corynebacterium diphtheriae from a clinical specimen, or
  • Histopathologic diagnosis of diphtheria

Case classification:

Probable: a clinically compatible case that is not laboratory confirmed and is not epidemiologically linked to a laboratory-confirmed case

Confirmed: a clinically compatible case that is either laboratory confirmed or epidemiologically linked to a laboratory-confirmed case

From the CDC guidelines: Cutaneous diphtheria should not be reported. Respiratory disease caused by nontoxigenic C. diphtheriae should be reported as diphtheria. All diphtheria isolates, regardless of association with disease, should be sent to the Diphtheria Laboratory, National Center for Infectious Diseases, CDC.


The first version of this article was adapted from the CDC document "Diphtheria - 1995 Case Definition" at http://www.cdc.gov/epo/dphsi/casedef/diphtheria_current.htm
As a work of an agency of the U.S. Government without any other copyright notice it should be available as a public domain resource.