Epitestosterone: Difference between revisions
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'''Epitestosterone'' is a natural [[steroid]], an inactive [[isomer]] of the hormone [[testosterone]]. [[Epitestosterone]] is believed to form in a similar way to testosterone; however, the exact site of its formation is unknown. Furthermore, exogenous administration of [[testosterone]] does not affect levels of |
'''Epitestosterone''' is a natural [[steroid]], an inactive [[isomer]] of the hormone [[testosterone]]. [[Epitestosterone]] is believed to form in a similar way to testosterone; however, the exact site of its formation is unknown. Furthermore, exogenous administration of [[testosterone]] does not affect levels of epitestosterone in the body. |
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As a result, tests to determine the ratio of testosterone to epitestosterone in urine are used to find athletes who are [[Doping (Sport)|doping]]. A normal healthy person has a ratio of about 1:1 testosterone to epitestosterone (T/E ratio) in their urine <ref> {{cite news | url=http://www.asada.gov.au/substances/facts/testosterone.htm | title=Substances: Testosterone to epitestosterone (T/E) ratio | publisher=Australian Government | date=Tuesday, February 28, 2006}}</ref>. |
As a result, tests to determine the ratio of testosterone to epitestosterone in urine are used to find athletes who are [[Doping (Sport)|doping]]. A normal healthy person has a ratio of about 1:1 testosterone to epitestosterone (T/E ratio) in their urine <ref> {{cite news | url=http://www.asada.gov.au/substances/facts/testosterone.htm | title=Substances: Testosterone to epitestosterone (T/E) ratio | publisher=Australian Government | date=Tuesday, February 28, 2006}}</ref>. |
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Revision as of 01:27, 3 August 2006
| File:Epitestosterone.gif | |
| Identifiers | |
|---|---|
| |
| CAS Number | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.169.813 |
| Chemical and physical data | |
| Formula | C19H28O2 |
| Molar mass | 288.42 |
Epitestosterone is a natural steroid, an inactive isomer of the hormone testosterone. Epitestosterone is believed to form in a similar way to testosterone; however, the exact site of its formation is unknown. Furthermore, exogenous administration of testosterone does not affect levels of epitestosterone in the body.
As a result, tests to determine the ratio of testosterone to epitestosterone in urine are used to find athletes who are doping. A normal healthy person has a ratio of about 1:1 testosterone to epitestosterone (T/E ratio) in their urine [1].
Although epitestosterone has not been shown to enhance athletic performance, administration of epistestosterone can be used to mask a high level of testosterone if the standard T/E ratio test is used. As such, epitestosterone is banned by many sporting authorities as a masking agent for testosterone.
Urine test taken from Floyd Landis, winner of the 2006 Tour de France showed "an unusual level of testosterone/epitestosterone", in violation of the 4:1 limit imposed by the race organizers. Although this suggested doping, it may have been caused by a low epitestosterone level rather than an artificially elevated testosterone level. Landis has also claimed that an elevated testosterone level could be related to his hypothyroidism.
External links
Notes
- ^ "Substances: Testosterone to epitestosterone (T/E) ratio". Australian Government. Tuesday, February 28, 2006.
{{cite news}}: Check date values in:|date=(help)