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Epistestosterone and Testosterone: landis had an 11:1 level
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Although epitestosterone has not been shown to enhance athletic performance, administration of epistestosterone can be used to mask a high level of testosterone if the standard T/E ratio test is used. As such, epitestosterone is banned by many sporting authorities as a masking agent for testosterone.
Although epitestosterone has not been shown to enhance athletic performance, administration of epistestosterone can be used to mask a high level of testosterone if the standard T/E ratio test is used. As such, epitestosterone is banned by many sporting authorities as a masking agent for testosterone.


Urine test taken from [[Floyd Landis]], winner of the [[2006 Tour de France]] showed "an unusual level of testosterone/epitestosterone", in violation of the 4:1 limit imposed by the race organizers. Although this suggested doping, it may have been caused by a low epitestosterone level rather than an artificially elevated testosterone level. Landis has also claimed that an elevated testosterone level could be related to his [[hypothyroidism]].
Urine test taken from [[Floyd Landis]], winner of the [[2006 Tour de France]] showed "an unusual level of testosterone/epitestosterone" of 11:1, in violation of the 4:1 limit imposed by the race organizers. Although this suggested doping, it may have been caused by a low epitestosterone level rather than an artificially elevated testosterone level. Landis has also claimed that an elevated testosterone level could be related to his [[hypothyroidism]].


== External links ==
== External links ==

Revision as of 08:56, 4 August 2006

Epitestosterone
File:Epitestosterone.gif
Identifiers
  • 17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17- dodecahydrocyclopenta[a]phenanthren-3-one
CAS Number
CompTox Dashboard (EPA)
ECHA InfoCard100.169.813 Edit this at Wikidata
Chemical and physical data
FormulaC19H28O2
Molar mass288.42

Epitestosterone is a natural steroid, an inactive isomer of the hormone testosterone. Epitestosterone is believed to form in a similar way to testosterone; however, the exact site of its formation is unknown. It has been shown to accumulate in mammary cyst fluid and in the prostate. Epitestosterone levels are typically highest in young males; however, by adulthood, most healthy males exhibit a testosterone to epitestosterone ratio (T/E ratio) of about 1:1[1].

Epistestosterone and Testosterone

It has been shown that exogenous administration of testosterone does not affect levels of epitestosterone in the body. As a result, tests to determine the ratio of testosterone to epitestosterone in urine are used to find athletes who are doping. A normal healthy person has a ratio of about 1:1 testosterone to epitestosterone (T/E ratio) in their urine

Although epitestosterone has not been shown to enhance athletic performance, administration of epistestosterone can be used to mask a high level of testosterone if the standard T/E ratio test is used. As such, epitestosterone is banned by many sporting authorities as a masking agent for testosterone.

Urine test taken from Floyd Landis, winner of the 2006 Tour de France showed "an unusual level of testosterone/epitestosterone" of 11:1, in violation of the 4:1 limit imposed by the race organizers. Although this suggested doping, it may have been caused by a low epitestosterone level rather than an artificially elevated testosterone level. Landis has also claimed that an elevated testosterone level could be related to his hypothyroidism.

Notes

  1. ^ "Substances: Testosterone to epitestosterone (T/E) ratio". Australian Government. Tuesday, February 28, 2006. {{cite news}}: Check date values in: |date= (help)