Flavonol 3-sulfotransferase: Difference between revisions
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In [[enzymology]], a '''flavonol 3-sulfotransferase''' ({{EC number|2.8.2.25}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]] |
In [[enzymology]], a '''flavonol 3-sulfotransferase''' ({{EC number|2.8.2.25}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]] |
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:3'-phosphoadenylyl sulfate + flavonol<math>\rightleftharpoons</math> adenosine 3',5'-bisphosphate + flavonol 3-sulfate |
:3'-phosphoadenylyl sulfate + flavonol<math>\rightleftharpoons</math> adenosine 3',5'-bisphosphate + flavonol 3-sulfate |
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Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3'-phosphoadenylyl sulfate]] and a [[flavonol]], whereas its two [[product (chemistry)|products]] are [[adenosine 3',5'-bisphosphate]] and [[flavonol 3-sulfate]]. A specific examples of a flavonol that can act as a substrate is [[quercetin]]. |
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3'-phosphoadenylyl sulfate]] and a [[flavonol]], whereas its two [[product (chemistry)|products]] are [[adenosine 3',5'-bisphosphate]] and [[flavonol 3-sulfate]]. A specific examples of a flavonol that can act as a substrate is [[quercetin]].<ref>{{cite journal |doi=10.1104/pp.90.3.977 |title=Partial Purification and Characterization of Three Flavonol-Specific Sulfotransferases from ''Flaveria chloraefolia'' |year=1989 |last1=Varin |first1=Luc |last2=Ibrahim |first2=Ragai K. |journal=Plant Physiology |volume=90 |issue=3 |pages=977–81 |pmid=16666908 |pmc=1061831}}</ref> |
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This enzyme belongs to the family of [[transferase]]s termed the [[sulfotransferase]]s, which transfer sulfate groups. The systematic name of this enzyme class is '''3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase'''. |
This enzyme belongs to the family of [[transferase]]s termed the [[sulfotransferase]]s, which transfer sulfate groups. The systematic name of this enzyme class is '''3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase'''. |
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==References== |
==References== |
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* {{cite journal |doi=10.1104/pp.90.3.977 |title=Partial Purification and Characterization of Three Flavonol-Specific Sulfotransferases from ''Flaveria chloraefolia'' |year=1989 |last1=Varin |first1=Luc |last2=Ibrahim |first2=Ragai K. |journal=Plant Physiology |volume=90 |issue=3 |pages=977–81 |pmid=16666908 |pmc=1061831}} |
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{{Sulfur-containing group transferases}} |
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{{transferase-stub}} |
{{transferase-stub}} |
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Revision as of 03:28, 9 January 2016
| flavonol 3-sulfotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.8.2.25 | ||||||||
| CAS no. | 121855-10-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a flavonol 3-sulfotransferase (EC 2.8.2.25) is an enzyme that catalyzes the chemical reaction
- 3'-phosphoadenylyl sulfate + flavonol adenosine 3',5'-bisphosphate + flavonol 3-sulfate
Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and a flavonol, whereas its two products are adenosine 3',5'-bisphosphate and flavonol 3-sulfate. A specific examples of a flavonol that can act as a substrate is quercetin.[1]
This enzyme belongs to the family of transferases termed the sulfotransferases, which transfer sulfate groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase.
References
- ^ Varin, Luc; Ibrahim, Ragai K. (1989). "Partial Purification and Characterization of Three Flavonol-Specific Sulfotransferases from Flaveria chloraefolia". Plant Physiology. 90 (3): 977–81. doi:10.1104/pp.90.3.977. PMC 1061831. PMID 16666908.