Ent-isokaurene C2-hydroxylase: Difference between revisions
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'''Ent-isokaurene C2-hydroxylase''' ({{EC number|1.14.13.143}}, ''CYP71Z6'') is an [[enzyme]] with systematic name ''ent-isokaurene,NADPH:oxygen oxidoreductase (hydroxylating)''.<ref>{{cite journal | title = Parsing a multifunctional biosynthetic gene cluster from rice: biochemical characterization of CYP71Z6 & 7 |author = Wu, Y., Hillwig, M.L., Wang, Q. and Peters, R.J. |journal = FEBS Lett. |year = 2011 |volume = 585 |pages = 3446–3451 |pmid = 21985968 |doi=10.1016/j.febslet.2011.09.038 |issue=21 |pmc=3227696}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]] |
'''Ent-isokaurene C2-hydroxylase''' ({{EC number|1.14.13.143}}, ''CYP71Z6'') is an [[enzyme]] with [[List of enzymes|systematic name]] ''ent-isokaurene,NADPH:oxygen oxidoreductase (hydroxylating)''.<ref>{{cite journal | title = Parsing a multifunctional biosynthetic gene cluster from rice: biochemical characterization of CYP71Z6 & 7 |author = Wu, Y., Hillwig, M.L., Wang, Q. and Peters, R.J. |journal = FEBS Lett. |year = 2011 |volume = 585 |pages = 3446–3451 |pmid = 21985968 |doi=10.1016/j.febslet.2011.09.038 |issue=21 |pmc=3227696}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]] |
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: ent-isokaurene + O<sub>2</sub> + NADPH + H<sup>+</sup> <math>\rightleftharpoons</math> ent-2alpha-hydroxyisokaurene + H<sub>2</sub>O + NADP<sup>+</sup> |
: ent-isokaurene + O<sub>2</sub> + NADPH + H<sup>+</sup> <math>\rightleftharpoons</math> ent-2alpha-hydroxyisokaurene + H<sub>2</sub>O + NADP<sup>+</sup> |
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Revision as of 20:01, 30 March 2016
| Ent-isokaurene C2-hydroxylase | |||||||||
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| Identifiers | |||||||||
| EC no. | 1.14.13.143 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Ent-isokaurene C2-hydroxylase (EC 1.14.13.143, CYP71Z6) is an enzyme with systematic name ent-isokaurene,NADPH:oxygen oxidoreductase (hydroxylating).[1] This enzyme catalyses the following chemical reaction
- ent-isokaurene + O2 + NADPH + H+ ent-2alpha-hydroxyisokaurene + H2O + NADP+
Ent-isokaurene C2-hydroxylase performs the initial step in the conversion of ent-isokaurene to the antibacterial oryzalides in rice, Oryza sativa.
References
- ^ Wu, Y., Hillwig, M.L., Wang, Q. and Peters, R.J. (2011). "Parsing a multifunctional biosynthetic gene cluster from rice: biochemical characterization of CYP71Z6 & 7". FEBS Lett. 585 (21): 3446–3451. doi:10.1016/j.febslet.2011.09.038. PMC 3227696. PMID 21985968.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
External links
- Ent-isokaurene+C2-hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)