TRA (gene): Difference between revisions

TRA
Identifiers
Aliases	TRA, IMD7, TCRA, TRA@, TRAC, T-cell receptor alpha locus, TCRD, T cell receptor alpha locus
External IDs	GeneCards: TRA; OMA:TRA - orthologs
Orthologs
	6955
	n/a
	n/a
	n/a
	P0DSE1
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
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Revision as of 02:18, 6 June 2016

T-cell receptor alpha chain C region is a protein that in humans is encoded by the TRA@ gene.^[2]^[3]^[4]

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References

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Erikson J, Williams DL, Finan J, Nowell PC, Croce CM (Sep 1985). "Locus of the alpha-chain of the T-cell receptor is split by chromosome translocation in T-cell leukemias". Science. 229 (4715): 784–6. doi:10.1126/science.3875152. PMID 3875152.
^ Rabbitts TH, Lefranc MP, Stinson MA, Sims JE, Schroder J, Steinmetz M, Spurr NL, Solomon E, Goodfellow PN (Oct 1985). "The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia". EMBO J. 4 (6): 1461–5. PMC 554368. PMID 3875483.
^ "Entrez Gene: TRA@ T cell receptor alpha locus".

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 {{Infobox_gene}}
-'''T-cell receptor alpha chain C region''' is a [[protein]] that in humans is encoded by the ''TRA@'' [[gene]].<ref name="pmid3875152">{{cite journal | author = Erikson J, Williams DL, Finan J, Nowell PC, Croce CM | title = Locus of the alpha-chain of the T-cell receptor is split by chromosome translocation in T-cell leukemias | journal = Science | volume = 229 | issue = 4715 | pages = 784–6 |date=Sep 1985 | pmid = 3875152 | pmc =  | doi =10.1126/science.3875152  }}</ref><ref name="pmid3875483">{{cite journal | author = Rabbitts TH, Lefranc MP, Stinson MA, Sims JE, Schroder J, Steinmetz M, Spurr NL, Solomon E, Goodfellow PN | title = The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia | journal = EMBO J | volume = 4 | issue = 6 | pages = 1461–5 |date=Oct 1985 | pmid = 3875483 | pmc = 554368 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TRA@ T cell receptor alpha locus| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6955| accessdate = }}</ref>
+'''T-cell receptor alpha chain C region''' is a [[protein]] that in humans is encoded by the ''TRA@'' [[gene]].<ref name="pmid3875152">{{cite journal |vauthors=Erikson J, Williams DL, Finan J, Nowell PC, Croce CM | title = Locus of the alpha-chain of the T-cell receptor is split by chromosome translocation in T-cell leukemias | journal = Science | volume = 229 | issue = 4715 | pages = 784–6 |date=Sep 1985 | pmid = 3875152 | pmc =  | doi =10.1126/science.3875152  }}</ref><ref name="pmid3875483">{{cite journal |vauthors=Rabbitts TH, Lefranc MP, Stinson MA, Sims JE, Schroder J, Steinmetz M, Spurr NL, Solomon E, Goodfellow PN | title = The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia | journal = EMBO J | volume = 4 | issue = 6 | pages = 1461–5 |date=Oct 1985 | pmid = 3875483 | pmc = 554368 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TRA@ T cell receptor alpha locus| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6955| accessdate = }}</ref>
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 *{{cite journal  | author=Kenwrick S |title=Isolation and sequence of two genes associated with a CpG island 5' of the factor VIII gene |journal=Hum. Mol. Genet. |volume=1 |issue= 3 |pages= 179–86 |year= 1993 |pmid= 1303175 |doi=10.1093/hmg/1.3.179  |name-list-format=vanc| author2=Levinson B  | author3=Taylor S  | display-authors=3  | last4=Shapiro  | first4=Amy  | last5=Gitschier  | first5=Jane  }}
 *{{cite journal  | author=Suzuki CK |title=Regulating the retention of T-cell receptor alpha chain variants within the endoplasmic reticulum: Ca(2+)-dependent association with BiP |journal=J. Cell Biol. |volume=114 |issue= 2 |pages= 189–205 |year= 1991 |pmid= 1649196 |doi=10.1083/jcb.114.2.189  | pmc=2289081  |name-list-format=vanc| author2=Bonifacino JS  | author3=Lin AY  | display-authors=3  | last4=Davis  | first4=MM  | last5=Klausner  | first5=RD  }}
-*{{cite journal  | author=Travis A, Amsterdam A, Belanger C, Grosschedl R |title=LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected] |journal=Genes Dev. |volume=5 |issue= 5 |pages= 880–94 |year= 1991 |pmid= 1827423 |doi=10.1101/gad.5.5.880  }}
+*{{cite journal  |vauthors=Travis A, Amsterdam A, Belanger C, Grosschedl R |title=LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected] |journal=Genes Dev. |volume=5 |issue= 5 |pages= 880–94 |year= 1991 |pmid= 1827423 |doi=10.1101/gad.5.5.880  }}
-*{{cite journal  | author=Koning F, Maloy WL, Coligan JE |title=The implications of subunit interactions for the structure of the T cell receptor-CD3 complex |journal=Eur. J. Immunol. |volume=20 |issue= 2 |pages= 299–305 |year= 1990 |pmid= 2138083 |doi=10.1002/eji.1830200211  }}
+*{{cite journal  |vauthors=Koning F, Maloy WL, Coligan JE |title=The implications of subunit interactions for the structure of the T cell receptor-CD3 complex |journal=Eur. J. Immunol. |volume=20 |issue= 2 |pages= 299–305 |year= 1990 |pmid= 2138083 |doi=10.1002/eji.1830200211  }}
 *{{cite journal  | author=Dyer MJ |title=T-cell receptor delta/alpha rearrangements in lymphoid neoplasms |journal=Blood |volume=74 |issue= 3 |pages= 1073–83 |year= 1989 |pmid= 2546634 |doi=  }}
-*{{cite journal  | author=Chilson OP, Kelly-Chilson AE |title=Mitogenic lectins bind to the antigen receptor on human lymphocytes |journal=Eur. J. Immunol. |volume=19 |issue= 2 |pages= 389–96 |year= 1989 |pmid= 2703017 |doi=10.1002/eji.1830190225  }}
+*{{cite journal  |vauthors=Chilson OP, Kelly-Chilson AE |title=Mitogenic lectins bind to the antigen receptor on human lymphocytes |journal=Eur. J. Immunol. |volume=19 |issue= 2 |pages= 389–96 |year= 1989 |pmid= 2703017 |doi=10.1002/eji.1830190225  }}
 *{{cite journal  | author=Yanagi Y |title=Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=82 |issue= 10 |pages= 3430–4 |year= 1985 |pmid= 3873654 |doi=10.1073/pnas.82.10.3430  | pmc=397789  |name-list-format=vanc| author2=Chan A  | author3=Chin B  | display-authors=3  | last4=Minden  | first4=M  | last5=Mak  | first5=TW  }}
 *{{cite journal  | author=Sim GK |title=Primary structure of human T-cell receptor alpha-chain |journal=Nature |volume=312 |issue= 5996 |pages= 771–5 |year= 1985 |pmid= 6440030 |doi=10.1038/312771a0  |name-list-format=vanc| author2=Yagüe J  | author3=Nelson J  | display-authors=3  | last4=Marrack  | first4=Philippa  | last5=Palmer  | first5=Edward  | last6=Augustin  | first6=Andrei  | last7=Kappler  | first7=John  }}
-*{{cite journal  | author=Kearse KP, Roberts JL, Singer A |title=TCR alpha-CD3 delta epsilon association is the initial step in alpha beta dimer formation in murine T cells and is limiting in immature CD4+ CD8+ thymocytes |journal=Immunity |volume=2 |issue= 4 |pages= 391–9 |year= 1995 |pmid= 7719941 |doi= 10.1016/1074-7613(95)90147-7 }}
+*{{cite journal  |vauthors=Kearse KP, Roberts JL, Singer A |title=TCR alpha-CD3 delta epsilon association is the initial step in alpha beta dimer formation in murine T cells and is limiting in immature CD4+ CD8+ thymocytes |journal=Immunity |volume=2 |issue= 4 |pages= 391–9 |year= 1995 |pmid= 7719941 |doi= 10.1016/1074-7613(95)90147-7 }}
-*{{cite journal  | author=Manolios N, Kemp O, Li ZG |title=The T cell antigen receptor alpha and beta chains interact via distinct regions with CD3 chains |journal=Eur. J. Immunol. |volume=24 |issue= 1 |pages= 84–92 |year= 1994 |pmid= 8020575 |doi=10.1002/eji.1830240114  }}
+*{{cite journal  |vauthors=Manolios N, Kemp O, Li ZG |title=The T cell antigen receptor alpha and beta chains interact via distinct regions with CD3 chains |journal=Eur. J. Immunol. |volume=24 |issue= 1 |pages= 84–92 |year= 1994 |pmid= 8020575 |doi=10.1002/eji.1830240114  }}
-*{{cite journal  | author=Bagga R, Emerson BM |title=An HMG I/Y-containing repressor complex and supercoiled DNA topology are critical for long-range enhancer-dependent transcription in vitro |journal=Genes Dev. |volume=11 |issue= 5 |pages= 629–39 |year= 1997 |pmid= 9119227 |doi=10.1101/gad.11.5.629  }}
+*{{cite journal  |vauthors=Bagga R, Emerson BM |title=An HMG I/Y-containing repressor complex and supercoiled DNA topology are critical for long-range enhancer-dependent transcription in vitro |journal=Genes Dev. |volume=11 |issue= 5 |pages= 629–39 |year= 1997 |pmid= 9119227 |doi=10.1101/gad.11.5.629  }}
-*{{cite journal  | author=San José E, Sahuquillo AG, Bragado R, Alarcón B |title=Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/gamma dimers associate indistinctly with both TCR alpha and TCR beta chains. Evidence for a double TCR heterodimer model |journal=Eur. J. Immunol. |volume=28 |issue= 1 |pages= 12–21 |year= 1998 |pmid= 9485181 |doi=10.1002/(SICI)1521-4141(199801)28:01<12::AID-IMMU12>3.0.CO;2-9  }}
+*{{cite journal  |vauthors=San José E, Sahuquillo AG, Bragado R, Alarcón B |title=Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/gamma dimers associate indistinctly with both TCR alpha and TCR beta chains. Evidence for a double TCR heterodimer model |journal=Eur. J. Immunol. |volume=28 |issue= 1 |pages= 12–21 |year= 1998 |pmid= 9485181 |doi=10.1002/(SICI)1521-4141(199801)28:01<12::AID-IMMU12>3.0.CO;2-9  }}
 *{{cite journal  | author=Ding YH |title=Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids |journal=Immunity |volume=8 |issue= 4 |pages= 403–11 |year= 1998 |pmid= 9586631 |doi=10.1016/S1074-7613(00)80546-4  |name-list-format=vanc| author2=Smith KJ  | author3=Garboczi DN  | display-authors=3  | last4=Utz  | first4=Ursula  | last5=Biddison  | first5=William E.  | last6=Wiley  | first6=Don C.  }}
 *{{cite journal  | author=Kirchgessner H |title=The Transmembrane Adaptor Protein Trim Regulates T Cell Receptor (Tcr) Expression and Tcr-Mediated Signaling via an Association with the Tcr ζ Chain |journal=J. Exp. Med. |volume=193 |issue= 11 |pages= 1269–84 |year= 2001 |pmid= 11390434 |doi=10.1084/jem.193.11.1269  | pmc=2193385  |name-list-format=vanc| author2=Dietrich J  | author3=Scherer J  | display-authors=3  | last4=Isomaki  | first4=P.  | last5=Korinek  | first5=V.  | last6=Hilgert  | first6=I.  | last7=Bruyns  | first7=E.  | last8=Leo  | first8=A.  | last9=Cope  | first9=A. P.  }}
 *{{cite journal  | author=Shelton JG |title=Importance of the T cell receptor alpha-chain transmembrane distal region for assembly with cognate subunits |journal=Mol. Immunol. |volume=38 |issue= 4 |pages= 259–65 |year= 2001 |pmid= 11566319 |doi=10.1016/S0161-5890(01)00062-1  |name-list-format=vanc| author2=Gülland S  | author3=Nicolson K  | display-authors=3  | last4=Kearse  | first4=Kelly P  | last5=Thomas Bäckström  | first5=B  }}
 *{{cite journal  | author=Pietra G |title=The analysis of the natural killer-like activity of human cytolytic T lymphocytes revealed HLA-E as a novel target for TCR alpha/beta-mediated recognition |journal=Eur. J. Immunol. |volume=31 |issue= 12 |pages= 3687–93 |year= 2002 |pmid= 11745389 |doi=10.1002/1521-4141(200112)31:12<3687::AID-IMMU3687>3.0.CO;2-C  |name-list-format=vanc| author2=Romagnani C  | author3=Falco M  | display-authors=3  | last4=Vitale  | first4=Massimo  | last5=Castriconi  | first5=Roberta  | last6=Pende  | first6=Daniela  | last7=Millo  | first7=Enrico  | last8=Anfossi  | first8=Simone  | last9=Biassoni  | first9=Roberto  }}
-*{{cite journal  | author=Hennecke J, Wiley DC |title=Structure of a Complex of the Human α/β T Cell Receptor (TCR) HA1.7, Influenza Hemagglutinin Peptide, and Major Histocompatibility Complex Class II Molecule, HLA-DR4 (DRA0101 and DRB10401): Insight into TCR Cross-Restriction and Alloreactivity |journal=J. Exp. Med. |volume=195 |issue= 5 |pages= 571–81 |year= 2002 |pmid= 11877480 |doi=10.1084/jem.20011194  | pmc=2193773  }}
+*{{cite journal  |vauthors=Hennecke J, Wiley DC |title=Structure of a Complex of the Human α/β T Cell Receptor (TCR) HA1.7, Influenza Hemagglutinin Peptide, and Major Histocompatibility Complex Class II Molecule, HLA-DR4 (DRA0101 and DRB10401): Insight into TCR Cross-Restriction and Alloreactivity |journal=J. Exp. Med. |volume=195 |issue= 5 |pages= 571–81 |year= 2002 |pmid= 11877480 |doi=10.1084/jem.20011194  | pmc=2193773  }}
 *{{cite journal  | author=García P |title=Human T cell receptor-mediated recognition of HLA-E |journal=Eur. J. Immunol. |volume=32 |issue= 4 |pages= 936–44 |year= 2002 |pmid= 11920559 |doi=10.1002/1521-4141(200204)32:4<936::AID-IMMU936>3.0.CO;2-M  |name-list-format=vanc| author2=Llano M  | author3=de Heredia AB  | display-authors=3  | last4=Willberg  | first4=Christian B.  | last5=Caparrós  | first5=Esther  | last6=Aparicio  | first6=Pedro  | last7=Braud  | first7=Véronique M.  | last8=López-Botet  | first8=Miguel  }}
 }}

Revision as of 02:18, 6 June 2016

References

Further reading