Rauvolfia serpentina: Difference between revisions
| Line 48: | Line 48: | ||
==Medicinal uses== |
==Medicinal uses== |
||
{{medref|section|date=March 2016}} |
|||
The plant is known for curing various disorders{{dubious|date=March 2016}} because of the presence of [[alkaloids]], [[carbohydrates]], [[flavonoids]], [[glycosides]], [[phlobatannins]], [[phenols]], [[resins]], [[saponins]], [[tannins]] and [[terpenes]]. |
|||
The extract of the plant has |
The extract of the plant has been used for millennia in [[India]] – [[Alexander the Great]] administered this plant to cure his general [[Ptolemy I Soter]] of a poisoned arrow. It was reported that [[Mahatma Gandhi]] took it as a [[tranquilizer]] during his lifetime.<ref>[http://www.time.com/time/magazine/article/0,9171,857672,00.html Pills for Mental Illness?], ''[[TIME Magazine]]'', November 8, 1954</ref> It has been used to treat insect stings and the bites of venomous reptiles. The plant also contains [[reserpine]], was used in an attempt to treat [[high blood pressure]] and mental disorders including [[schizophrenia]], and had a brief period of popularity for that purpose in the West from 1954 to 1957.<ref name="isharwal">{{Cite journal | title = Rustom Jal Vakil: his contributions to cardiology | author = Sumit Isharwal and Shubham Gupta | pmc = 1524711 | pmid = 16878618 | journal = [[Texas Heart Institute Journal]] | year = 2006 | volume = 33 | issue = 2 | pages = 161–170 }}</ref> R. serpentina is also known for its [[antimicrobial]], [[antifungal]], [[anti-inflammatory]], [[antiproliferative]], [[antidiuretic]] and [[anticholinergic]] activities.<ref name="globalresearchonline.net"/> |
||
Recent research has proved that Rauwolfia serpentina exhibits |
Recent research has proved that Rauwolfia serpentina exhibits activity against drug-resistant tumor cells.<ref>{{cite journal | url = http://www.sciencedirect.com/science/article/pii/S0944711315000215 | doi=10.1016/j.phymed.2015.01.002 | volume=22 | title=Cytotoxicity of the indole alkaloid reserpine from Rauwolfia serpentina against drug-resistant tumor cells | journal=Phytomedicine | pages=308–318}}</ref> |
||
It is one of the [[Chinese herbology#50 fundamental herbs|50 fundamental herbs]] used in [[traditional Chinese medicine]], where it has the name ''shégēn mù'' ({{zh|c=[[wiktionary:蛇|蛇]][[wiktionary:根|根]][[wiktionary:木|木]]}}) or ''yìndù shémù'' ({{zh|c=[[wiktionary:印|印]][[wiktionary:度|度]][[wiktionary:蛇|蛇]][[wiktionary:木|木]]}}). |
It is one of the [[Chinese herbology#50 fundamental herbs|50 fundamental herbs]] used in [[traditional Chinese medicine]], where it has the name ''shégēn mù'' ({{zh|c=[[wiktionary:蛇|蛇]][[wiktionary:根|根]][[wiktionary:木|木]]}}) or ''yìndù shémù'' ({{zh|c=[[wiktionary:印|印]][[wiktionary:度|度]][[wiktionary:蛇|蛇]][[wiktionary:木|木]]}}). |
||
Revision as of 12:48, 19 October 2016
| Rauvolfia serpentina | |
|---|---|
| |
| Scientific classification | |
| Kingdom: | |
| (unranked): | |
| (unranked): | |
| (unranked): | |
| Order: | |
| Family: | |
| Genus: | |
| Species: | R. serpentina
|
| Binomial name | |
| Rauvolfia serpentina | |
| Synonyms[2] | |
| |
Rauvolfia serpentina, or Indian snakeroot is a species of flower in the family Apocynaceae. It is native to the Indian subcontinent and East Asia (from India to Indonesia).[3][4] Common English names include devil pepper and snakeroot.
Vernacular names
English: serpentine wood[5] Bengali: Chandra; Hindi: Chandrabagha, Chota chand; Kannada: Patalagondhi, Sarpagandhi,Shivavabhiballi, Sutranavi; Malayalam: Chuvanna-vilpori, Suvapavalforiyan; Marathi: Harkaya, Harki; Oriya:Patalgarur, Sanochada; Tamil: Chivan amelpodi; Telgu: Paataala garuda, Paataala goni; Urdu: Asrel.[6] indonesia : pule pandak;
Chemical composition
Rauvolfia serpentina The plant contains more than 50 different alkaloids which belong to the monoterpenoid indole alkaloid family. The major alkaloids are ajmaline, ajmalicine, ajmalimine, deserpidine, indobine, indobinine, reserpine, reserpiline, rescinnamine, rescinnamidine, serpentine, serpentinine and yohimbine.[7]
Medicinal uses
The extract of the plant has been used for millennia in India – Alexander the Great administered this plant to cure his general Ptolemy I Soter of a poisoned arrow. It was reported that Mahatma Gandhi took it as a tranquilizer during his lifetime.[8] It has been used to treat insect stings and the bites of venomous reptiles. The plant also contains reserpine, was used in an attempt to treat high blood pressure and mental disorders including schizophrenia, and had a brief period of popularity for that purpose in the West from 1954 to 1957.[9] R. serpentina is also known for its antimicrobial, antifungal, anti-inflammatory, antiproliferative, antidiuretic and anticholinergic activities.[7]
Recent research has proved that Rauwolfia serpentina exhibits activity against drug-resistant tumor cells.[10]
It is one of the 50 fundamental herbs used in traditional Chinese medicine, where it has the name shégēn mù (Chinese: 蛇根木) or yìndù shémù (Chinese: 印度蛇木).
Other uses
The wood, commonly known as serpentwood, is mildly popular amongst woodcarving and woodturning hobbyists.[citation needed]
See also
References
- ^ "Module 11: Ayurvedic". Retrieved 2008-02-11.
- ^ "The Plant List: A Working List of All Plant Species". Retrieved 12 April 2015.
- ^ eFloras. "Rauvolfia serpentina". Flora of China. Missouri Botanical Garden, St. Louis, MO & Harvard University Herbaria, Cambridge, MA. Retrieved 9 April 2012.
- ^ Oudhia, P. and Tripathi, R.S. (2002). Identification, cultivation and export of important medicinal plants. In Proc. National Seminar on Horticulture Development in Chhattisgarh: Vision and Vistas. Indira Gandhi Agricultural University, Raipur (India) 21-23 Jan. 2002:78-85.
- ^ NRCS. "Rauvolfia serpentina". PLANTS Database. United States Department of Agriculture (USDA). Retrieved 19 October 2015.
- ^ http://www.bsienvis.nic.in/CITES/R.%20serpentina.pdf
- ^ a b http://www.globalresearchonline.net/journalcontents/v23-2/56.pdf
- ^ Pills for Mental Illness?, TIME Magazine, November 8, 1954
- ^ Sumit Isharwal and Shubham Gupta (2006). "Rustom Jal Vakil: his contributions to cardiology". Texas Heart Institute Journal. 33 (2): 161–170. PMC 1524711. PMID 16878618.
- ^ "Cytotoxicity of the indole alkaloid reserpine from Rauwolfia serpentina against drug-resistant tumor cells". Phytomedicine. 22: 308–318. doi:10.1016/j.phymed.2015.01.002.