Nesvacumab: Difference between revisions
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'''Nesvacumab''' is |
'''Nesvacumab''' is an experimental [[monoclonal antibody]] originally designed for the treatment of cancer. It targets the protein [[angiopoietin 2]].<ref>[http://www.ama-assn.org/resources/doc/usan/nesvacumab.pdf Statement On A Nonproprietary Name Adopted By The USAN Council - Nesvacumab], ''[[American Medical Association]]''.</ref> {{as of|2017|5}}, it is in [[Phase II clinical trial]]s for the treatment of [[diabetic macular edema]].<ref>{{clinicalTrialsGov|NCT02713204|Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection (ONYX)}}</ref><ref>{{clinicalTrialsGov|NCT02712008|Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema (RUBY)}}</ref> |
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This drug |
This drug is being developed by [[Regeneron]] Pharmaceuticals. |
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== References == |
== References == |
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[[Category:Monoclonal antibodies]] |
[[Category:Monoclonal antibodies]] |
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[[Category:Experimental cancer drugs]] |
[[Category:Experimental cancer drugs]] |
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Revision as of 08:11, 1 May 2017
Monoclonal antibody | |
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Type | Whole antibody |
Source | Human |
Target | Angiopoietin 2 |
Clinical data | |
ATC code |
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Legal status | |
Legal status |
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Identifiers | |
CAS Number | |
IUPHAR/BPS | |
ChemSpider |
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KEGG | |
Chemical and physical data | |
Formula | C6440H9966N1722O2008S38 |
Molar mass | 144.9 kg/mol g·mol−1 |
Nesvacumab is an experimental monoclonal antibody originally designed for the treatment of cancer. It targets the protein angiopoietin 2.[1] As of May 2017[update], it is in Phase II clinical trials for the treatment of diabetic macular edema.[2][3]
This drug is being developed by Regeneron Pharmaceuticals.
References
- ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Nesvacumab, American Medical Association.
- ^ Clinical trial number NCT02713204 for "Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection (ONYX)" at ClinicalTrials.gov
- ^ Clinical trial number NCT02712008 for "Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema (RUBY)" at ClinicalTrials.gov