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'''Nesvacumab''' is a monoclonal antibody designed for the treatment of cancer.<ref>[http://www.ama-assn.org/resources/doc/usan/nesvacumab.pdf Statement On A Nonproprietary Name Adopted By The USAN Council - Nesvacumab], ''[[American Medical Association]]''.</ref>
'''Nesvacumab''' is an experimental [[monoclonal antibody]] originally designed for the treatment of cancer. It targets the protein [[angiopoietin 2]].<ref>[http://www.ama-assn.org/resources/doc/usan/nesvacumab.pdf Statement On A Nonproprietary Name Adopted By The USAN Council - Nesvacumab], ''[[American Medical Association]]''.</ref> {{as of|2017|5}}, it is in [[Phase II clinical trial]]s for the treatment of [[diabetic macular edema]].<ref>{{clinicalTrialsGov|NCT02713204|Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection (ONYX)}}</ref><ref>{{clinicalTrialsGov|NCT02712008|Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema (RUBY)}}</ref>


This drug was developed by Regeneron Pharmaceuticals.
This drug is being developed by [[Regeneron]] Pharmaceuticals.


== References ==
== References ==
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{{monoclonal-antibody-stub}}
[[Category:Monoclonal antibodies]]
[[Category:Monoclonal antibodies]]
[[Category:Experimental cancer drugs]]
[[Category:Experimental cancer drugs]]


{{monoclonal-antibody-stub}}

Revision as of 08:11, 1 May 2017

Nesvacumab
Monoclonal antibody
TypeWhole antibody
SourceHuman
TargetAngiopoietin 2
Clinical data
ATC code
  • none
Legal status
Legal status
  • Investigational
Identifiers
CAS Number
IUPHAR/BPS
ChemSpider
  • none
KEGG
Chemical and physical data
FormulaC6440H9966N1722O2008S38
Molar mass144.9 kg/mol g·mol−1

Nesvacumab is an experimental monoclonal antibody originally designed for the treatment of cancer. It targets the protein angiopoietin 2.[1] As of May 2017, it is in Phase II clinical trials for the treatment of diabetic macular edema.[2][3]

This drug is being developed by Regeneron Pharmaceuticals.

References

  1. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Nesvacumab, American Medical Association.
  2. ^ Clinical trial number NCT02713204 for "Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection (ONYX)" at ClinicalTrials.gov
  3. ^ Clinical trial number NCT02712008 for "Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema (RUBY)" at ClinicalTrials.gov