User:Jeileee/sandbox: Difference between revisions
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Other examples of open microfluidics are suspended microfluidics, hanging droplet microfluidics in which droplets are hanging on wires (fiber/thread/yarn based microfluidics), and rail-based microfluidics For example, suspended microfluidic devices have been used to study cellular diffusion and migration [in what kind of environment?], while rail-based microfluidics can be used for micropatterning and the study of cell communication. |
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Examples of open-microfluidics examples open-channel microfluidics, droplets hanging on wires (fiber/thread/yarn based microfluidics) and channels with comb like rails (rail-based microfluidics and [[Electrowetting|EWOD]]), and suspended microfluidics,<ref name=":0" /><ref name=":2" /><ref>{{Cite journal|last=Lorenceau|first=Élise|last2=Clanet|first2=Christophe|last3=Quéré|first3=David|date=2004-11-01|title=Capturing drops with a thin fiber|url=http://www.sciencedirect.com/science/article/pii/S0021979704005727|journal=Journal of Colloid and Interface Science|volume=279|issue=1|pages=192–197|doi=10.1016/j.jcis.2004.06.054}}</ref><ref>{{Cite journal|last=Satoh|first=Wataru|last2=Hosono|first2=Hiroki|last3=Suzuki|first3=Hiroaki|date=2005-11-01|title=On-Chip Microfluidic Transport and Mixing Using Electrowetting and Incorporation of Sensing Functions|url=http://dx.doi.org/10.1021/ac050821s|journal=Analytical Chemistry|volume=77|issue=21|pages=6857–6863|doi=10.1021/ac050821s|issn=0003-2700}}</ref><ref name=":3">{{Cite journal|last=Casavant|first=Benjamin P.|last2=Berthier|first2=Erwin|last3=Theberge|first3=Ashleigh B.|last4=Berthier|first4=Jean|last5=Montanez-Sauri|first5=Sara I.|last6=Bischel|first6=Lauren L.|last7=Brakke|first7=Kenneth|last8=Hedman|first8=Curtis J.|last9=Bushman|first9=Wade|date=2013-06-18|title=Suspended microfluidics|url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690848/|journal=Proceedings of the National Academy of Sciences of the United States of America|volume=110|issue=25|pages=10111–10116|doi=10.1073/pnas.1302566110|issn=0027-8424|pmc=PMC3690848|pmid=23729815}}</ref> Suspended microfluidic devices have been used in studying cell diffusion and migration.<ref name=":3" /> Rail-based microfluidics device can form microchambers where cells are stored and cell communication is studied.<ref name=":0" /> |
Examples of open-microfluidics examples open-channel microfluidics, droplets hanging on wires (fiber/thread/yarn based microfluidics) and channels with comb like rails (rail-based microfluidics and [[Electrowetting|EWOD]]), and suspended microfluidics,<ref name=":0" /><ref name=":2" /><ref>{{Cite journal|last=Lorenceau|first=Élise|last2=Clanet|first2=Christophe|last3=Quéré|first3=David|date=2004-11-01|title=Capturing drops with a thin fiber|url=http://www.sciencedirect.com/science/article/pii/S0021979704005727|journal=Journal of Colloid and Interface Science|volume=279|issue=1|pages=192–197|doi=10.1016/j.jcis.2004.06.054}}</ref><ref>{{Cite journal|last=Satoh|first=Wataru|last2=Hosono|first2=Hiroki|last3=Suzuki|first3=Hiroaki|date=2005-11-01|title=On-Chip Microfluidic Transport and Mixing Using Electrowetting and Incorporation of Sensing Functions|url=http://dx.doi.org/10.1021/ac050821s|journal=Analytical Chemistry|volume=77|issue=21|pages=6857–6863|doi=10.1021/ac050821s|issn=0003-2700}}</ref><ref name=":3">{{Cite journal|last=Casavant|first=Benjamin P.|last2=Berthier|first2=Erwin|last3=Theberge|first3=Ashleigh B.|last4=Berthier|first4=Jean|last5=Montanez-Sauri|first5=Sara I.|last6=Bischel|first6=Lauren L.|last7=Brakke|first7=Kenneth|last8=Hedman|first8=Curtis J.|last9=Bushman|first9=Wade|date=2013-06-18|title=Suspended microfluidics|url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690848/|journal=Proceedings of the National Academy of Sciences of the United States of America|volume=110|issue=25|pages=10111–10116|doi=10.1073/pnas.1302566110|issn=0027-8424|pmc=PMC3690848|pmid=23729815}}</ref> Suspended microfluidic devices have been used in studying cell diffusion and migration.<ref name=":3" /> Rail-based microfluidics device can form microchambers where cells are stored and cell communication is studied.<ref name=":0" /> |
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Revision as of 23:08, 14 May 2017
Critique an article
Hi,
The first source from FDA is from 2007, it would be best to get an updated version if available since many changes could occur during 10 years of period. The information of source 14, 15, 19, 21 seem to from blog posts and webpages that could be replaced by peer-reviewed articles. The link to source 51,52,53 does not work. Another section that could be added to this article is how gluten is detected. For example an overview of immunological and spectroscopic methods such as gas chromatography, mass spectrometer, ELISA, and commercially available ELISA kit.
Jei1 08:43, 7 April 2017 (UTC)
 | This is a user sandbox of Jeileee. You can use it for testing or practicing edits. This is not the sandbox where you should draft your assigned article for a dashboard.wikiedu.org course. To find the right sandbox for your assignment, visit your Dashboard course page and follow the Sandbox Draft link for your assigned article in the My Articles section. |
Add to an article
In open Microfluidics, (open-surface microfluidics or open-surface microfluidics one of the boundaries of a channel is removed, so that the system is exposed to air. One of the main advantages of open channels are ease of accessibility to the flowing liquid and large liquid-gas surface area. Open channels allow the ability of intervening the system at any time, and this is useful to add or remove reagents. In closed channels, air bubbls formation could be in an issue, but in open channels this is no longer the case. In open-channels, the main flow is driven by spontanous capillary flow. Problem that could arise is evaporation, but that can be solved by maintaining the temperature Droplets can be stabilized by applying an electrical field. When both the top and bottom of a device is removed we will have suspended microfluidics.
Draft your article
In open Microfluidics, (open-surface microfluidics or open-surface microfluidics one of the boundaries of a channel is removed, so that the system is exposed to air. One of the many advantages of open channels are ease of accessibility to the flowing liquid, large liquid-gas surface area, robustness, functionality, and ease of fabrication. Open channels allow the ability of intervening the system at any time, and this is useful to add or remove reagents and samples such as tissues and cells.
CE.
In closed channels, air bubles formation could be in an issue, but in open channels this is no longer the case. In open-channels, the main flow is driven by spontaneous capillary flow (SCF).
When both the ceiling and floor of a device are removed we will have suspended microfluidics. The fluid flow is still driven by SCF.
Open microfluidics when implemented in the biololyg field can simulate the environment better because of no consraints.
Microcanal.
moving droplets.
Draft 1
Open Microfluidics
In open microfluidics, (open-surface microfluidics, open-space microfluidics), one of the boundaries of a system is removed, and the system is exposed to air or another interface.[1][2][3][4] One of the main advantages of open microfluidics is ease of accessibility and intervention to the flowing liquid in the system at any time, and this is helpful in adding or removing reagents. Compared to a closed system, when of the boundaries of a system is removed, a larger liquid-gas surface area exists, and this enables gas-liquid reactions to be performed.[1][5] Further, open systems minimize and even eliminates bubbles formation, a problem commonly found in closed system.[1]
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Other examples of open microfluidics are suspended microfluidics, hanging droplet microfluidics in which droplets are hanging on wires (fiber/thread/yarn based microfluidics), and rail-based microfluidics For example, suspended microfluidic devices have been used to study cellular diffusion and migration [in what kind of environment?], while rail-based microfluidics can be used for micropatterning and the study of cell communication.
Examples of open-microfluidics examples open-channel microfluidics, droplets hanging on wires (fiber/thread/yarn based microfluidics) and channels with comb like rails (rail-based microfluidics and EWOD), and suspended microfluidics,[1][2][6][7][8] Suspended microfluidic devices have been used in studying cell diffusion and migration.[8] Rail-based microfluidics device can form microchambers where cells are stored and cell communication is studied.[1]
In closed channel microfluidic devices, the main flow in the channels are driven by pressure via pumps (syringe pumps), external syringes or valves (trigger valves) and laminar flow is such an example.[1] CITE. On the other hand, in an open channel system, the flow is mainly driven passively. One of the main flow for in open channels is by................... by spontaneous capillary flow (SCF).[1] The closed channel system will have an inlet port filled with the carrier fluid, and SCF occurs if the Laplace pressure in the inlet is negative.[1] Chemical wettability and surface modification control the flow of the liquid in the channel and allow the fluid to stay confined in the channel.[3] One of the problem that could occur in an open channel is overflow, and this can be controlled by surface wetting preferentiality where the carrier fluid for example prefers to wet the floor of the channel more than the side walls.[2] Another problem in an open system is evaporation, but this can be controlled for example by covering the carrier fluid with a film of oil and maintaining the surrounding temperature.[9]
The free boundary in open microfluidics allows liquid-liquid and liquid-air interactions, where interfacial tensions occurs.[3] When two droplets of different sizes in the channel meet, they will fuse together forming one bigger droplet in the channel due to differences in Laplace pressure.[3] Therefore, the interfacial surface tensions in the open channel restricts the liquid to be of constant mean curvature to be stable in the open channel.[3] Droplet stability can be achieved by applying an electrical field.[10] On the other hand, certain drop shapes observed in closed channels allows for higher fluorescence sensitivity detection.[10]
Like many microfluidics, open system microfluidics can be applied in nanotechnology, biotechnology, fuel cells and space technology.[1][4] For cell-based studies, open channels devices allow the access of cells with micropipettes while the cells are in the channel and enables probing of single cells.[11] Other applications of open microfluidics are open capillary gel electrophoresis, water-in-oil emulsification.[9][2]
Future direction Point of care . home care[1]
Notes
- ^ a b c d e f g h i j Jean., Berthier, (2016-01-01). Open Microfluidics. John Wiley & Sons. ISBN 1118720806. OCLC 941538295.
{{cite book}}: CS1 maint: extra punctuation (link) CS1 maint: multiple names: authors list (link) - ^ a b c d Li, C.; Boban, M.; Tuteja, A. (2017-04-11). "Open-channel, water-in-oil emulsification in paper-based microfluidic devices". Lab Chip. 17 (8): 1436–1441. doi:10.1039/c7lc00114b. ISSN 1473-0189.
- ^ a b c d e Pfohl, Thomas; Mugele, Frieder; Seemann, Ralf; Herminghaus, Stephan (2003-12-15). "Trends in Microfluidics with Complex Fluids". ChemPhysChem. 4 (12): 1291–1298. doi:10.1002/cphc.200300847. ISSN 1439-7641.
- ^ a b Kaigala, Govind V.; Lovchik, Robert D.; Delamarche, Emmanuel (2012-11-05). "Microfluidics in the "Open Space" for Performing Localized Chemistry on Biological Interfaces". Angewandte Chemie International Edition. 51 (45): 11224–11240. doi:10.1002/anie.201201798. ISSN 1521-3773.
- ^ Zhao, Bin; Moore, Jeffrey S.; Beebe, David J. (2001-02-09). "Surface-Directed Liquid Flow Inside Microchannels". Science. 291 (5506): 1023–1026. doi:10.1126/science.291.5506.1023. ISSN 0036-8075. PMID 11161212.
- ^ Lorenceau, Élise; Clanet, Christophe; Quéré, David (2004-11-01). "Capturing drops with a thin fiber". Journal of Colloid and Interface Science. 279 (1): 192–197. doi:10.1016/j.jcis.2004.06.054.
- ^ Satoh, Wataru; Hosono, Hiroki; Suzuki, Hiroaki (2005-11-01). "On-Chip Microfluidic Transport and Mixing Using Electrowetting and Incorporation of Sensing Functions". Analytical Chemistry. 77 (21): 6857–6863. doi:10.1021/ac050821s. ISSN 0003-2700.
- ^ a b Casavant, Benjamin P.; Berthier, Erwin; Theberge, Ashleigh B.; Berthier, Jean; Montanez-Sauri, Sara I.; Bischel, Lauren L.; Brakke, Kenneth; Hedman, Curtis J.; Bushman, Wade (2013-06-18). "Suspended microfluidics". Proceedings of the National Academy of Sciences of the United States of America. 110 (25): 10111–10116. doi:10.1073/pnas.1302566110. ISSN 0027-8424. PMC 3690848. PMID 23729815.
{{cite journal}}: CS1 maint: PMC format (link) - ^ a b Gutzweiler, Ludwig; Gleichmann, Tobias; Tanguy, Laurent; Koltay, Peter; Zengerle, Roland; Riegger, Lutz (2017-04-01). "Open microfluidic gel electrophoresis: Rapid and low cost separation and analysis of DNA at the nanoliter scale". ELECTROPHORESIS: n/a–n/a. doi:10.1002/elps.201700001. ISSN 1522-2683.
- ^ a b Wang, Weiqiang; Jones, Thomas B. (2015-05-05). "Moving droplets between closed and open microfluidic systems". Lab Chip. 15 (10): 2201–2212. doi:10.1039/c5lc00014a. ISSN 1473-0189.
- ^ Hsu, Chia-Hsien; Chen, Chihchen; Folch, Albert (2004-10-07). ""Microcanals" for micropipette access to single cells in microfluidic environments". Lab Chip. 4 (5): 420–424. doi:10.1039/b404956j. ISSN 1473-0189.