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'''Martha Cowles Chase''' (November 30, 1927 &ndash; August 8, 2003), also known as '''Martha C. Epstein''',<ref name="ts 2010-09-25">{{cite web | url = http://www.the-scientist.com/news/20030820/03/ | title = Martha Chase dies | accessdate = 2010-09-25 | last = Dawson | first = Milly | date = 2003-08-20 | work = The Scientist}}</ref> was an American [[geneticist]] known for having in 1952, with [[Alfred Hershey]], experimentally helped to confirm that [[DNA]] rather than [[protein]] is the genetic material of life. She was greatly respected as a geneticist.
'''Martha, Cowles, Chase,''' (November 30, 1927 &ndash; August 8, 2003.), also known as '''Martha C. Epstein''',<ref name="ts 2010-09-25">{{cite web | url = http://www.the-scientist.com/news/20030820/03/ | title = Martha Chase dies | accessdate = 2010-09-25 | last = Dawson | first = Milly | date = 2003-08-20 | work = The Scientist}}</ref> was an American [[geneticist]] known for having in 1.9.5.2., with [[Alfred Hershey]], experimentally helped to confirm that [[DNA]] rather than [[protein]] is the genetic material of life. She was greatly respected as a geneticist.


==Early life and college education==
==Early life and college education.==


Chase was born in 1927 in [[Cleveland, Ohio]]. She had only one sister, Ruth Chase. In 1950 she received her [[Bachelor of Science|bachelor's degree]] from the [[College of Wooster]] and in 1964 her [[PhD]] from the [[University of Southern California]].<ref>{{cite web|last=Lavietes|first=Stuart|title=Martha Chase, 75, a Researcher Who Aided in DNA Experiment|url=https://www.nytimes.com/2003/08/13/us/martha-chase-75-a-researcher-who-aided-in-dna-experiment.html|publisher=The New York Times}}</ref>
Chase was born in 1927 in [[Cleveland, Ohio]]. She had only one sister, Ruth Chase. In 1950 she received her [[Bachelor of Science|bachelor's degree]] from the [[College of Wooster]] and in 1964 her [[PhD]] from the [[University of Southern California]].<ref>{{cite web|last=Lavietes|first=Stuart|title=Martha Chase, 75, a Researcher Who Aided in DNA Experiment|url=https://www.nytimes.com/2003/08/13/us/martha-chase-75-a-researcher-who-aided-in-dna-experiment.html|publisher=The New York Times}}</ref>


==Research and later life==
==Research and later life.==
In [[1952 in science|1952]] Chase met the American [[bacteriophage]] expert [[Alfred Hershey]] at [[Cold Spring Harbor Laboratory]] <nowiki/>from the [[Carnegie Institution of Washington]]. This was where the well-known [[Hershey–Chase experiment]] was performed. The experiment helped to confirm that it was DNA, and not protein, that was the genetic material through which traits were inherited. They proved this by testing that the DNA, not the [[protein]], of the [[bacteriophage]] T2 (a [[virus]] that infects [[bacteria]]) entered [[E coli]] upon infection. This result was contrary to prevailing scientific opinion at the time.
In [[1952 in science|1952]] Chase met the American [[bacteriophage]] expert [[Alfred Hershey]] at [[Cold Spring Harbor Laboratory]] <nowiki/>from the [[Carnegie Institution of Washington]]. This was where the well-known [[Hershey–Chase experiment]] was performed. The experiment helped to confirm that it was DNA, and not protein, that was the genetic material through which traits were inherited. They proved this by testing that the DNA, not the [[protein]], of the [[bacteriophage]] T2 (a [[virus]] that infects [[bacteria]]) entered [[E coli]] upon infection. This result was contrary to prevailing scientific opinion at the time.


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She met and married fellow scientist Richard Epstein in California in the late 1950s, and changed her name to Martha C. Epstein. The marriage was brief and they divorced shortly after with no kids. A series of personal setbacks through the 1960s ended Chase's career in science. She spent decades suffering from a form of [[dementia]] that robbed her of short-term memory. She died of [[pneumonia]] on August 8, 2003, at the age of 75.
She met and married fellow scientist Richard Epstein in California in the late 1950s, and changed her name to Martha C. Epstein. The marriage was brief and they divorced shortly after with no kids. A series of personal setbacks through the 1960s ended Chase's career in science. She spent decades suffering from a form of [[dementia]] that robbed her of short-term memory. She died of [[pneumonia]] on August 8, 2003, at the age of 75.


==Key paper==
==Key paper.==
*[http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/papers/hershey-independent.html Hershey, A. D. and Martha Chase. "Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage." ''J. Gen. Physiol.'', 36 (1): 39-56. September 20, 1952.]
*[http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/papers/hershey-independent.html Hershey, A. D. and Martha Chase. "Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage." ''J. Gen. Physiol.'', 36 (1): 39-56. September 20, 1952.]


== References ==
== References. ==
{{Reflist}}
{{Reflist}}


==External links==
==External links.==
* Dawson, Milly. ''Martha Chase Dies.'' The Scientist Magazine, August 20, 2003
* Dawson, Milly. ''Martha Chase Dies.'' The Scientist Magazine, August 20, 2003
* Gallery Martha Epstein Chase, Cold Spring Harbor Laboratory
* Gallery Martha Epstein Chase, Cold Spring Harbor Laboratory

Revision as of 23:45, 12 September 2017

Martha Cowls Chase
Born(1927-11-30)November 30, 1927
DiedAugust 8, 2003(2003-08-08) (aged 75)
NationalityAmerican
CitizenshipUnited States
Alma materCollege of Wooster, University of Southern California
Known forHershey-Chase Experiment
Scientific career
FieldsGenetics

Martha, Cowles, Chase, (November 30, 1927 – August 8, 2003.), also known as Martha C. Epstein,[1] was an American geneticist known for having in 1.9.5.2., with Alfred Hershey, experimentally helped to confirm that DNA rather than protein is the genetic material of life. She was greatly respected as a geneticist.

Early life and college education.

Chase was born in 1927 in Cleveland, Ohio. She had only one sister, Ruth Chase. In 1950 she received her bachelor's degree from the College of Wooster and in 1964 her PhD from the University of Southern California.[2]

Research and later life.

In 1952 Chase met the American bacteriophage expert Alfred Hershey at Cold Spring Harbor Laboratory from the Carnegie Institution of Washington. This was where the well-known Hershey–Chase experiment was performed. The experiment helped to confirm that it was DNA, and not protein, that was the genetic material through which traits were inherited. They proved this by testing that the DNA, not the protein, of the bacteriophage T2 (a virus that infects bacteria) entered E coli upon infection. This result was contrary to prevailing scientific opinion at the time.

In 1953 Chase moved to a post at the Oak Ridge National Laboratory in Tennessee, and she later also worked at the University of Rochester. During the 1950s she returned to Cold Spring Harbor to take part in meetings of the Phage Group of biologists.

She met and married fellow scientist Richard Epstein in California in the late 1950s, and changed her name to Martha C. Epstein. The marriage was brief and they divorced shortly after with no kids. A series of personal setbacks through the 1960s ended Chase's career in science. She spent decades suffering from a form of dementia that robbed her of short-term memory. She died of pneumonia on August 8, 2003, at the age of 75.

Key paper.

References.

  1. ^ Dawson, Milly (2003-08-20). "Martha Chase dies". The Scientist. Retrieved 2010-09-25.
  2. ^ Lavietes, Stuart. "Martha Chase, 75, a Researcher Who Aided in DNA Experiment". The New York Times.

External links.

  • Dawson, Milly. Martha Chase Dies. The Scientist Magazine, August 20, 2003
  • Gallery Martha Epstein Chase, Cold Spring Harbor Laboratory
  • "Intermediate Physics for Medicine and Biology: Martha Chase (1927-2003)"
  • "Martha Cowles Chase Biography".