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== Biography ==
== Biography ==
Born on 2 December 1944 in [[Kolkata]], in the Indian state of [[West Bengal]] to Bhabaranjan-Malancha couple, Bhattacharyya graduated in chemistry from the [[University of Calcutta]] and secured his master's degree in physical chemistry from the same university.<ref name="Indian Fellow - Bhattacharya" /> Subsequently, he joined the Indian Association for the Cultivation of Science, Kolkata and pursued his doctoral studies to secure the degree under the guidance of Uma Shankar Nandi of the [[Indian Institute of Science]]. Moving to the US, he completed his post-doctoral studies at the laboratory of Jan Wolff of the [[National Institutes of Health]]. He returned to India in 1976 to join [[Bose Institute]] as a [[Council of Scientific and Industrial Research|CSIR]] pool officer where he shifted to academics as a lecturer in 1978 and continued his service till his superannuation as a professor and head of the department of biochemistry.<ref name="Fellow profile - Indian Academy of Sciences">{{cite web | url=http://www.ias.ac.in/describe/fellow/Bhattacharyya,_Prof._Bhabatarak | title=Fellow profile - Indian Academy of Sciences | publisher=Indian Academy of Sciences | date=2016 | accessdate=September 30, 2016}}</ref> He has also been associated with [[Presidency College, Calcutta]] as a professor at their Department of Chemistry and Biochemistry.<ref name="Department of Chemistry and Biochemistry">{{cite web | url=http://www.presiuniv.ac.in/web/chemistry.php | title=Department of Chemistry and Biochemistry | publisher=Presidency University | date=2016 | accessdate=October 3, 2016}}</ref>
Born on December 2nd, 1944 in [[Kolkata]], in the Indian state of [[West Bengal]] to Bhabaranjan-Malancha couple, Bhattacharyya graduated in chemistry from the [[University of Calcutta]] and secured his master's degree in physical chemistry from the same university.<ref name="Indian Fellow - Bhattacharya" /> Subsequently, he joined the Indian Association for the Cultivation of Science, Kolkata and pursued his doctoral studies to secure the degree under the guidance of Uma Shankar Nandi of the [[Indian Institute of Science]]. Moving to the US, he completed his post-doctoral studies at the laboratory of Jan Wolff of the [[National Institutes of Health]]. He returned to India in 1976 to join [[Bose Institute]] as a [[Council of Scientific and Industrial Research|CSIR]] pool officer where he shifted to academics as a lecturer in 1978 and continued his service till his superannuation as a professor and head of the department of biochemistry.<ref name="Fellow profile - Indian Academy of Sciences">{{cite web | url=http://www.ias.ac.in/describe/fellow/Bhattacharyya,_Prof._Bhabatarak | title=Fellow profile - Indian Academy of Sciences | publisher=Indian Academy of Sciences | date=2016 | accessdate=September 30, 2016}}</ref> He has also been associated with [[Presidency College, Calcutta]] as a professor at their Department of Chemistry and Biochemistry.<ref name="Department of Chemistry and Biochemistry">{{cite web | url=http://www.presiuniv.ac.in/web/chemistry.php | title=Department of Chemistry and Biochemistry | publisher=Presidency University | date=2016 | accessdate=October 3, 2016}}</ref>


Bhattacharyya's early work during his post-doctoral studies at Jan Wolff's laboratory were on [[tubulin]] and its binding mechanism with [[antimitotic]] drugs.<ref name="Indian Fellow - Bhattacharya" /> Later, he focused his researches on colchicine-tubulin interaction and elucidated the effect of the ''carbonyl group on the side chain of B-ring'' in the irreversible binding of [[colchicine]].<ref name="Handbook of Shanti Swarup Bhatnagar Prize Winners">{{cite web | url=http://www.csirhrdg.res.in/ssb.pdf | title=Handbook of Shanti Swarup Bhatnagar Prize Winners | publisher=Council of Scientific and Industrial Research | date=1999 | accessdate=September 28, 2016 | pages=29}}</ref> He demonstrated the fluorescence of colchicine-tubilin bind which is reported to have offered an alternative to radio-labeled colchicine in pharmacological [[assays]] and made the study of the kinetics of colchicine binding easier. He studied the ''mechanism of chaperone-like activity of tubulin and microtubule associated proteins'' and his studies have known to be of significance in the design of lead compounds as well as new drugs for the treatment of cancer.<ref name="Faculty Bhabatarak Bhattacharyya">{{cite web | url=http://bic.boseinst.ernet.in/biochem/bablu.html | title=Faculty Bhabatarak Bhattacharyya | publisher=Bose Institute | date=2016 | accessdate=October 3, 2016}}</ref> He has published several articles detailing his research findings,<ref name="Bhabatarak Bhattacharyya on Microsoft Academic Search">{{cite web | url=http://65.54.113.26/Author/11083556/bhabatarak-bhattacharyya | title=Bhabatarak Bhattacharyya on Microsoft Academic Search | publisher=Microsoft Academic Search | date=2016 | accessdate=October 3, 2016}}</ref> has registered patents for his work<ref name="Patents by Inventor Abhik Saha">{{cite web | url=http://patents.justia.com/inventor/abhik-saha | title=Patents by Inventor Abhik Saha | publisher=Justia Patents | date=2016 | accessdate=October 3, 2016}}</ref> and has mentored many scholars in their doctoral studies.<ref name="Dr. Gopa Mitra">{{cite web | url=http://www.sjri.res.in/mmkeyperson/560 | title=Dr. Gopa Mitra | publisher=St. John's Research Institute | date=2016 | accessdate=October 3, 2016}}</ref><ref name="About Fellow">{{cite web | url=http://www.wellcomedbt.org/fellowsprofile/dr-abhik-saha-222 | title=About Fellow | publisher=Wellcome Trust | date=2016 | accessdate=October 3, 2016}}</ref> His scientific career has been documented in an article, ''Dr. Bablu Bhattacharyya: A Journey of Four Decades with Tubulin'', published in 2015.<ref name="Dr. Bablu Bhattacharyya: A Journey of Four Decades with Tubulin">{{cite journal | url=http://www.jpp.org.in/index.php/jpp/article/view/133 | title=Dr. Bablu Bhattacharyya: A Journey of Four Decades with Tubulin | author=Dulal Panda, Tapas K Manna | journal=Journal of Proteins and Proteomics | year=2015 | volume=6 | issue=3}}</ref> He has also been associated with the [[Council of Scientific and Industrial Research]], [[Department of Science and Technology (India)|Department of Science and Technology]],<ref name="Isothermal Titration Calorimetry">{{cite web | url=http://www.caluniv.ac.in/seminar/Workshop_Proteomics.pdf | title=Isothermal Titration Calorimetry | publisher=Calcutta University | date=2016 | accessdate=October 3, 2016}}</ref> [[Indian National Science Academy]] and the [[Indian Academy of Sciences]] as a member of their various technical committees.<ref name="Indian Fellow - Bhattacharya" />
Bhattacharyya's early work during his post-doctoral studies at Jan Wolff's laboratory were on [[tubulin]] and its binding mechanism with [[antimitotic]] drugs.<ref name="Indian Fellow - Bhattacharya" /> Later, he focused his researches on colchicine-tubulin interaction and elucidated the effect of the ''carbonyl group on the side chain of B-ring'' in the irreversible binding of [[colchicine]].<ref name="Handbook of Shanti Swarup Bhatnagar Prize Winners">{{cite web | url=http://www.csirhrdg.res.in/ssb.pdf | title=Handbook of Shanti Swarup Bhatnagar Prize Winners | publisher=Council of Scientific and Industrial Research | date=1999 | accessdate=September 28, 2016 | pages=29}}</ref> He demonstrated the fluorescence of colchicine-tubilin bind which is reported to have offered an alternative to radio-labeled colchicine in pharmacological [[assays]] and made the study of the kinetics of colchicine binding easier. He studied the ''mechanism of chaperone-like activity of tubulin and microtubule associated proteins'' and his studies have known to be of significance in the design of lead compounds as well as new drugs for the treatment of cancer.<ref name="Faculty Bhabatarak Bhattacharyya">{{cite web | url=http://bic.boseinst.ernet.in/biochem/bablu.html | title=Faculty Bhabatarak Bhattacharyya | publisher=Bose Institute | date=2016 | accessdate=October 3, 2016}}</ref> He has published several articles detailing his research findings,<ref name="Bhabatarak Bhattacharyya on Microsoft Academic Search">{{cite web | url=http://65.54.113.26/Author/11083556/bhabatarak-bhattacharyya | title=Bhabatarak Bhattacharyya on Microsoft Academic Search | publisher=Microsoft Academic Search | date=2016 | accessdate=October 3, 2016}}</ref> has registered patents for his work<ref name="Patents by Inventor Abhik Saha">{{cite web | url=http://patents.justia.com/inventor/abhik-saha | title=Patents by Inventor Abhik Saha | publisher=Justia Patents | date=2016 | accessdate=October 3, 2016}}</ref> and has mentored many scholars in their doctoral studies.<ref name="Dr. Gopa Mitra">{{cite web | url=http://www.sjri.res.in/mmkeyperson/560 | title=Dr. Gopa Mitra | publisher=St. John's Research Institute | date=2016 | accessdate=October 3, 2016}}</ref><ref name="About Fellow">{{cite web | url=http://www.wellcomedbt.org/fellowsprofile/dr-abhik-saha-222 | title=About Fellow | publisher=Wellcome Trust | date=2016 | accessdate=October 3, 2016}}</ref> His scientific career has been documented in an article, ''Dr. Bablu Bhattacharyya: A Journey of Four Decades with Tubulin'', published in 2015.<ref name="Dr. Bablu Bhattacharyya: A Journey of Four Decades with Tubulin">{{cite journal | url=http://www.jpp.org.in/index.php/jpp/article/view/133 | title=Dr. Bablu Bhattacharyya: A Journey of Four Decades with Tubulin | author=Dulal Panda, Tapas K Manna | journal=Journal of Proteins and Proteomics | year=2015 | volume=6 | issue=3}}</ref> He has also been associated with the [[Council of Scientific and Industrial Research]], [[Department of Science and Technology (India)|Department of Science and Technology]],<ref name="Isothermal Titration Calorimetry">{{cite web | url=http://www.caluniv.ac.in/seminar/Workshop_Proteomics.pdf | title=Isothermal Titration Calorimetry | publisher=Calcutta University | date=2016 | accessdate=October 3, 2016}}</ref> [[Indian National Science Academy]] and the [[Indian Academy of Sciences]] as a member of their various technical committees.<ref name="Indian Fellow - Bhattacharya" />

Revision as of 05:18, 23 September 2017

Bhabatarak Bhattacharyya
Born(1944-12-02)December 2, 1944
Kolkata, West Bengal, India
NationalityIndian
Alma mater
Known forFluorescence of colchicine
Awards1988 Shanti Swarup Bhatnagar Prize
P. S. Sharma Memorial Award
Bose Institute Foundation Day Award
Scientific career
Fields
Institutions
Doctoral advisorUma Shankar Nandi
Doctoral studentsGopa Mitra
Abhik Saha

Bhabatarak Bhattacharyya (born 1944), popularly known as Bablu Bhattacharyya, is an Indian structural biologist, biochemist and academic, known for his studies on the colchicine-tubulin interaction.[1] He is a former professor and the head of the department of biochemistry at the Bose Institute, Kolkata and an elected fellow of the Indian Academy of Sciences, Indian National Science Academy, National Academy of Sciences, India and The World Academy of Sciences.[2] The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1988, for his contributions to biological sciences.[3]

Biography

Born on December 2nd, 1944 in Kolkata, in the Indian state of West Bengal to Bhabaranjan-Malancha couple, Bhattacharyya graduated in chemistry from the University of Calcutta and secured his master's degree in physical chemistry from the same university.[2] Subsequently, he joined the Indian Association for the Cultivation of Science, Kolkata and pursued his doctoral studies to secure the degree under the guidance of Uma Shankar Nandi of the Indian Institute of Science. Moving to the US, he completed his post-doctoral studies at the laboratory of Jan Wolff of the National Institutes of Health. He returned to India in 1976 to join Bose Institute as a CSIR pool officer where he shifted to academics as a lecturer in 1978 and continued his service till his superannuation as a professor and head of the department of biochemistry.[4] He has also been associated with Presidency College, Calcutta as a professor at their Department of Chemistry and Biochemistry.[5]

Bhattacharyya's early work during his post-doctoral studies at Jan Wolff's laboratory were on tubulin and its binding mechanism with antimitotic drugs.[2] Later, he focused his researches on colchicine-tubulin interaction and elucidated the effect of the carbonyl group on the side chain of B-ring in the irreversible binding of colchicine.[6] He demonstrated the fluorescence of colchicine-tubilin bind which is reported to have offered an alternative to radio-labeled colchicine in pharmacological assays and made the study of the kinetics of colchicine binding easier. He studied the mechanism of chaperone-like activity of tubulin and microtubule associated proteins and his studies have known to be of significance in the design of lead compounds as well as new drugs for the treatment of cancer.[7] He has published several articles detailing his research findings,[8] has registered patents for his work[9] and has mentored many scholars in their doctoral studies.[10][11] His scientific career has been documented in an article, Dr. Bablu Bhattacharyya: A Journey of Four Decades with Tubulin, published in 2015.[12] He has also been associated with the Council of Scientific and Industrial Research, Department of Science and Technology,[13] Indian National Science Academy and the Indian Academy of Sciences as a member of their various technical committees.[2]

Awards and honors

The Council of Scientific and Industrial Research awarded him the Shanti Swarup Bhatnagar Prize, one of the highest Indian science awards in 1988. He is an elected fellow of several science academies including the Indian Academy of Sciences, Indian National Science Academy, the National Academy of Sciences, India[14] and The World Academy of Sciences.[15] He is also a recipient of the P. S. Sharma Memorial Award of the Society for Biological Chemists, India and the Foundation Day Award of Bose Institute.[2]

See also

References

  1. ^ "Brief Profile of the Awardee". Shanti Swarup Bhatnagar Prize. 2016. Retrieved September 28, 2016.
  2. ^ a b c d e "Indian Fellow - Bhattacharya". Indian National Science Academy. 2016. Retrieved September 30, 2016.
  3. ^ "View Bhatnagar Awardees". Shanti Swarup Bhatnagar Prize. 2016. Retrieved September 19, 2016.
  4. ^ "Fellow profile - Indian Academy of Sciences". Indian Academy of Sciences. 2016. Retrieved September 30, 2016.
  5. ^ "Department of Chemistry and Biochemistry". Presidency University. 2016. Retrieved October 3, 2016.
  6. ^ "Handbook of Shanti Swarup Bhatnagar Prize Winners" (PDF). Council of Scientific and Industrial Research. 1999. p. 29. Retrieved September 28, 2016.
  7. ^ "Faculty Bhabatarak Bhattacharyya". Bose Institute. 2016. Retrieved October 3, 2016.
  8. ^ "Bhabatarak Bhattacharyya on Microsoft Academic Search". Microsoft Academic Search. 2016. Retrieved October 3, 2016.
  9. ^ "Patents by Inventor Abhik Saha". Justia Patents. 2016. Retrieved October 3, 2016.
  10. ^ "Dr. Gopa Mitra". St. John's Research Institute. 2016. Retrieved October 3, 2016.
  11. ^ "About Fellow". Wellcome Trust. 2016. Retrieved October 3, 2016.
  12. ^ Dulal Panda, Tapas K Manna (2015). "Dr. Bablu Bhattacharyya: A Journey of Four Decades with Tubulin". Journal of Proteins and Proteomics. 6 (3).
  13. ^ "Isothermal Titration Calorimetry" (PDF). Calcutta University. 2016. Retrieved October 3, 2016.
  14. ^ "NASI fellows". National Academy of Sciences, India. 2016. Archived from the original on July 17, 2015. Retrieved October 3, 2016. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  15. ^ "TWAS fellow". TWAS. 2016. Retrieved October 3, 2016.
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