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Flavonol 3-sulfotransferase: Difference between revisions

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:3'-phosphoadenylyl sulfate + flavonol<math>\rightleftharpoons</math> adenosine 3',5'-bisphosphate + flavonol 3-sulfate
:3'-phosphoadenylyl sulfate + flavonol<math>\rightleftharpoons</math> adenosine 3',5'-bisphosphate + flavonol 3-sulfate


Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3'-phosphoadenylyl sulfate]] and a [[flavonol]], whereas its two [[product (chemistry)|products]] are [[adenosine 3',5'-bisphosphate]] and [[flavonol 3-sulfate]]. A specific examples of a flavonol that can act as a substrate is [[quercetin]].<ref>{{cite journal |doi=10.1104/pp.90.3.977 |title=Partial Purification and Characterization of Three Flavonol-Specific Sulfotransferases from ''Flaveria chloraefolia'' |year=1989 |last1=Varin |first1=Luc |last2=Ibrahim |first2=Ragai K. |journal=Plant Physiology |volume=90 |issue=3 |pages=977–81 |pmid=16666908 |pmc=1061831}}</ref>
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3'-phosphoadenylyl sulfate]] and a [[flavonol]], whereas its two [[product (chemistry)|products]] are [[adenosine 3',5'-bisphosphate]] and [[flavonol 3-sulfate]]. A specific examples of a flavonol that can act as a substrate is [[quercetin]].<ref>{{cite journal | vauthors = Varin L, Ibrahim RK | title = Partial Purification and Characterization of Three Flavonol-Specific Sulfotransferases from Flaveria chloraefolia | journal = Plant Physiology | volume = 90 | issue = 3 | pages = 977–81 | date = July 1989 | pmid = 16666908 | pmc = 1061831 | doi = 10.1104/pp.90.3.977 }}</ref>


This enzyme belongs to the family of [[transferase]]s termed the [[sulfotransferase]]s, which transfer sulfate groups. The [[List of enzymes|systematic name]] of this enzyme class is '''3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase'''.
This enzyme belongs to the family of [[transferase]]s termed the [[sulfotransferase]]s, which transfer sulfate groups. The [[List of enzymes|systematic name]] of this enzyme class is '''3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase'''.


==References==
== References ==
{{reflist|1}}
{{reflist}}


{{Sulfur-containing group transferases}}
{{Sulfur-containing group transferases}}

Revision as of 20:09, 15 March 2018

flavonol 3-sulfotransferase
Identifiers
EC no.2.8.2.25
CAS no.121855-10-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a flavonol 3-sulfotransferase (EC 2.8.2.25) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + flavonol adenosine 3',5'-bisphosphate + flavonol 3-sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and a flavonol, whereas its two products are adenosine 3',5'-bisphosphate and flavonol 3-sulfate. A specific examples of a flavonol that can act as a substrate is quercetin.[1]

This enzyme belongs to the family of transferases termed the sulfotransferases, which transfer sulfate groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase.

References

  1. ^ Varin L, Ibrahim RK (July 1989). "Partial Purification and Characterization of Three Flavonol-Specific Sulfotransferases from Flaveria chloraefolia". Plant Physiology. 90 (3): 977–81. doi:10.1104/pp.90.3.977. PMC 1061831. PMID 16666908.