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'''Cholemia''' is a condition caused by the presence of excess [[bile]] in the blood. Its symptoms can include [[somnolence]] (drowsiness) and, in extreme cases, [[coma]]. It is often an early sign of [[liver disease]].<ref>{{cite book |first=George S. |last=Weger |title=The Genesis and Control of Disease |year=1996 |publisher=[[Kessinger Publishing Company]] |isbn=978-1-56459-979-7 |page=525 |url=https://books.google.com/books?id=CDyqy80Vr4QC&pg=PA525}}</ref>
'''Cholemia''' is a condition caused by the presence of excess [[bile]] in the blood. Its symptoms can include [[somnolence]] (drowsiness), yellow tinge to skin and whites of eyes, fatigue, nausea and, in extreme cases, [[coma]]. It is often an early sign of [[liver disease]].<ref>{{cite book |first=George S. |last=Weger |title=The Genesis and Control of Disease |year=1996 |publisher=[[Kessinger Publishing Company]] |isbn=978-1-56459-979-7 |page=525 |url=https://books.google.com/books?id=CDyqy80Vr4QC&pg=PA525}}</ref>
==Cause==
==Cause==
Cholemia is caused by a blood disorder caused by [[genetics|genetic]] factors.
Cholemia is caused by a blood disorder caused by [[genetics|genetic]] factors.


==Diagnosis==
==Diagnosis==
It is caused by a disease of the liver. It is most commonly seen in patients with [[hepatitis b]]. It's confirmed by the diagnosis as it shows a higher level of bilirubin ( <3 mg/dl ) but it is necessary to rule out liver diseases if the diagnosis is uncertain.<ref>{{cite journal |last1=Gromashevskaia |first1=L. L. |last2=Kasatkina |first2=M. G. |year=1979 |script-title=uk:мы исследовали изоферменты щелочной фосфатазы в сыворотке крови |trans-title=Isoenzymes of blood serum alkaline phosphatase under experimental cholemia |language=Ukrainian |journal=Ukrainskii biokhimicheskii zhurnal |volume=51 |issue=5 |pages=459–62 |pmid=516178}}</ref>
There is no specific diagnostic test for this condition. Usually detected colonoscopy. It is caused by a disease of the liver. It is most commonly seen in patients with [[hepatitis b]]. It's confirmed by the diagnosis as it shows a higher level of bilirubin ( <3 mg/dl ) but it is necessary to rule out liver diseases if the diagnosis is uncertain.<ref>{{cite journal |last1=Gromashevskaia |first1=L. L. |last2=Kasatkina |first2=M. G. |year=1979 |script-title=uk:мы исследовали изоферменты щелочной фосфатазы в сыворотке крови |trans-title=Isoenzymes of blood serum alkaline phosphatase under experimental cholemia |language=Ukrainian |journal=Ukrainskii biokhimicheskii zhurnal |volume=51 |issue=5 |pages=459–62 |pmid=516178}}</ref>


==Treatment==
==Treatment==

Revision as of 15:44, 14 June 2018

Cholemia
Other namesHyperbilirubinemia type 1

Cholemia is a condition caused by the presence of excess bile in the blood. Its symptoms can include somnolence (drowsiness), yellow tinge to skin and whites of eyes, fatigue, nausea and, in extreme cases, coma. It is often an early sign of liver disease.[1]

Cause

Cholemia is caused by a blood disorder caused by genetic factors.

Diagnosis

There is no specific diagnostic test for this condition. Usually detected colonoscopy. It is caused by a disease of the liver. It is most commonly seen in patients with hepatitis b. It's confirmed by the diagnosis as it shows a higher level of bilirubin ( <3 mg/dl ) but it is necessary to rule out liver diseases if the diagnosis is uncertain.[2]

Treatment

Cholemia is currently untreatable.

References

  1. ^ Weger, George S. (1996). The Genesis and Control of Disease. Kessinger Publishing Company. p. 525. ISBN 978-1-56459-979-7.
  2. ^ Gromashevskaia, L. L.; Kasatkina, M. G. (1979). мы исследовали изоферменты щелочной фосфатазы в сыворотке крови [Isoenzymes of blood serum alkaline phosphatase under experimental cholemia]. Ukrainskii biokhimicheskii zhurnal (in Ukrainian). 51 (5): 459–62. PMID 516178.

Further reading

  • Green, J; Beyar, R; Sideman, S; Mordechovitz, D; Better, O. S. (1986). "The 'jaundiced heart': A possible explanation for postoperative shock in obstructive jaundice". Surgery. 100 (1): 14–20. PMID 3726756.
  • Green, Jacob; Beyar, Rafael; Bomzon, Lionel; Finberg, John P.M.; Better, Ori S. (1984). "Jaundice, the Circulation and the Kidney". Nephron. 37 (3): 145–52. doi:10.1159/000183235. PMID 6738765.
  • Fajers, Carl-Mabtin (2009). "Experimental Studies in Cholemic Nephrosis". Acta Pathologica Microbiologica Scandinavica. 41. doi:10.1111/j.1699-0463.1957.tb00996.x. PMID 13443982.