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{{nihongo|'''Minoru Shirota'''|代田 稔|Shirota Minoru|extra=April 23, 1899 – March 10, 1982}} was a [[Japan]]ese microbiologist. He was the inventor of [[Yakult]], the [[yogurt]]-like [[probiotic]] drink containing ''[[Lactobacillus]] casei'' strain Shirota.
{{nihongo|'''Minoru Shirota'''|代田 稔|Shirota Minoru|extra=April 23, 1899 – March 10, 1982}} was a [[Japan]]ese microbiologist. He was the inventor of [[Yakult]], the [[yogurt]]-like [[probiotic]] drink containing ''[[Lactobacillus]] casei'' strain Shirota.


Shirota was born in Inadani, a village near River Inadani Tenryuu in the area Iida, [[Nagano, Nagano|Western Nagano]], Japan. His family was prosperous in paper and silk worm-rearing business. His ambition turned to medicine as a number of children died in his village due to infectious diseases and malnutrition. In 1921 he entered [[Kyoto Imperial University]]'s School of Medicine. In 1940 he earned a PhD in medicine, and joined the faculty of medicine at Kyoto University. During the [[Second Sino-Japanese War|Japanese invasion of China]], he was appointed as a military doctor. Then he became a professor at the University Medical Harupin, China. After the war he returned to Japan to establish Shirota Research Centre in 1939. In 1950 he started Yakult company. In 1955 he moved its company headquarters to Tokyo.<ref>{{cite web|title=Success in the culture of intraintestinal lactic acid bacteria for the first time in the world by Minoru Shirota|url=http://www.japanese-greatest.com/biology-medicine/yakult.html|publisher=The World’s Greatest Japanese|accessdate=9 July 2014|date=1 March 2008}}</ref>
Shirota was born in Inadani, a village near River Inadani Tenryuu in the area Iida, [[Nagano, Nagano|Western Nagano]], Japan. His family was prosperous in paper and silk worm-rearing business. His ambition turned to medicine as a number of children died in his village due to infectious diseases and malnutrition. In 1921 he entered [[Kyoto Imperial University]]'s School of Medicine. In 1940 he earned a PhD in medicine, and joined the faculty of medicine at Kyoto University. During the [[Second Sino-Japanese War|Japanese invasion of China]], he was appointed as a military doctor. Then he became a professor at the University Medical Harupin, China. After the war he returned to Japan to establish Shirota Research Centre in 1939. In 1950 he started Yakult company. In 1955 he moved its company headquarters to Tokyo.


Inspired by the writings of [[Ilya Ilyich Mechnikov]], Shirota developed a stronger strain of [[lactic acid bacteria]] which might work to destroy the harmful bacteria living in the intestines, and therefore improve and maintain the health of human beings.<ref>{{cite journal|last1=Brown|first1=AC|last2=Valiere|first2=A|title=Probiotics and medical nutrition therapy.|journal=Nutrition in Clinical Care|year=2004|volume=7|issue=2|pages=56–68|pmid=15481739|pmc=1482314}}</ref><ref>{{cite book|last1=editors|first1=Joshua J. Malago, Jos. F.J.G. Koninkx, R. Marinsek-Logar,|title=Probiotic Bacteria and Enteric Infections Cytoprotection by Probiotic Bacteria|year=2011|publisher=Springer Science & Business Media|location=Dordrecht|isbn=978-9-4007-0386-5|page=6|url=https://books.google.com/books?id=Nv8xBMWOe4EC&dq}}</ref>
Inspired by the writings of [[Ilya Ilyich Mechnikov]], Shirota developed a stronger strain of [[lactic acid bacteria]] which might work to destroy the harmful bacteria living in the intestines, and therefore improve and maintain the health of human beings.<ref>{{cite journal|last1=Brown|first1=AC|last2=Valiere|first2=A|title=Probiotics and medical nutrition therapy.|journal=Nutrition in Clinical Care|year=2004|volume=7|issue=2|pages=56–68|pmid=15481739|pmc=1482314}}</ref><ref>{{cite book|last1=editors|first1=Joshua J. Malago, Jos. F.J.G. Koninkx, R. Marinsek-Logar,|title=Probiotic Bacteria and Enteric Infections Cytoprotection by Probiotic Bacteria|year=2011|publisher=Springer Science & Business Media|location=Dordrecht|isbn=978-9-4007-0386-5|page=6|url=https://books.google.com/books?id=Nv8xBMWOe4EC&dq}}</ref>

Revision as of 17:32, 5 September 2018

Minoru Shirota
Born
代田 稔 (Shirota Minoru)

(1899-04-23)23 April 1899
Died10 March 1982(1982-03-10) (aged 82)
Tokyo, Japan
OccupationMicrobiologist
Known forInvention of Yakult

Minoru Shirota (代田 稔, Shirota Minoru, April 23, 1899 – March 10, 1982) was a Japanese microbiologist. He was the inventor of Yakult, the yogurt-like probiotic drink containing Lactobacillus casei strain Shirota.

Shirota was born in Inadani, a village near River Inadani Tenryuu in the area Iida, Western Nagano, Japan. His family was prosperous in paper and silk worm-rearing business. His ambition turned to medicine as a number of children died in his village due to infectious diseases and malnutrition. In 1921 he entered Kyoto Imperial University's School of Medicine. In 1940 he earned a PhD in medicine, and joined the faculty of medicine at Kyoto University. During the Japanese invasion of China, he was appointed as a military doctor. Then he became a professor at the University Medical Harupin, China. After the war he returned to Japan to establish Shirota Research Centre in 1939. In 1950 he started Yakult company. In 1955 he moved its company headquarters to Tokyo.

Inspired by the writings of Ilya Ilyich Mechnikov, Shirota developed a stronger strain of lactic acid bacteria which might work to destroy the harmful bacteria living in the intestines, and therefore improve and maintain the health of human beings.[1][2]

The result of his efforts was the successful culturing of Lactobacillus casei strain shirota. Shirota then began working together with supporters to make a drink incorporating the strain. This led to the development of Yakult which was introduced to the market in 1935.[citation needed]

He died in Tokyo, Japan in 1982.[citation needed]

References

  1. ^ Brown, AC; Valiere, A (2004). "Probiotics and medical nutrition therapy". Nutrition in Clinical Care. 7 (2): 56–68. PMC 1482314. PMID 15481739.
  2. ^ editors, Joshua J. Malago, Jos. F.J.G. Koninkx, R. Marinsek-Logar, (2011). Probiotic Bacteria and Enteric Infections Cytoprotection by Probiotic Bacteria. Dordrecht: Springer Science & Business Media. p. 6. ISBN 978-9-4007-0386-5. {{cite book}}: |last1= has generic name (help)CS1 maint: extra punctuation (link) CS1 maint: multiple names: authors list (link)