Chlorphenesin carbamate: Difference between revisions
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Chlorophenesin carbamate (drug) <ref>https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+3031</ref> not to be confused with chlorophensin the preservative on EU Annex V/50.<ref>https://www.cir-safety.org/sites/default/files/Chlorp092012rep.pdf</ref> Tag: references removed |
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'''Chlorphenesin carbamate''' ('''Maolate''', '''Musil''') is a centrally acting [[muscle relaxant]] used to treat muscle pain and [[spasm]]s.<ref>{{cite journal | last1 = Okuyama | first1 = S | last2 = Aihara | first2 = H | title = Antinociceptive effect of chlorphenesin carbamate in adjuvant arthritic rats | journal = Research communications in chemical pathology and pharmacology | volume = 55 | issue = 2 | pages = 147–60 | year = 1987 | pmid = 3823606 }}</ref><ref>{{cite journal | last1 = Kurachi | first1 = M | last2 = Aihara | first2 = H | title = Effect of a muscle relaxant, chlorphenesin carbamate, on the spinal neurons of rats | journal = Japanese journal of pharmacology | volume = 36 | issue = 1 | pages = 7–13 | year = 1984 | pmid = 6503049 | doi = 10.1254/jjp.36.7 }}</ref> Chlorphenesin is no longer used for this purpose in most developed nations due to the availability of much safer spasmolytics such as [[benzodiazepines]]. |
'''Chlorphenesin carbamate''' ('''Maolate''', '''Musil''') is a centrally acting [[muscle relaxant]] used to treat muscle pain and [[spasm]]s.<ref>{{cite journal | last1 = Okuyama | first1 = S | last2 = Aihara | first2 = H | title = Antinociceptive effect of chlorphenesin carbamate in adjuvant arthritic rats | journal = Research communications in chemical pathology and pharmacology | volume = 55 | issue = 2 | pages = 147–60 | year = 1987 | pmid = 3823606 }}</ref><ref>{{cite journal | last1 = Kurachi | first1 = M | last2 = Aihara | first2 = H | title = Effect of a muscle relaxant, chlorphenesin carbamate, on the spinal neurons of rats | journal = Japanese journal of pharmacology | volume = 36 | issue = 1 | pages = 7–13 | year = 1984 | pmid = 6503049 | doi = 10.1254/jjp.36.7 }}</ref> Chlorphenesin is no longer used for this purpose in most developed nations due to the availability of much safer spasmolytics such as [[benzodiazepines]]. |
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Other central effects include sedation, [[anxiolytic|anxiolysis]], and dizziness. |
Other central effects include sedation, [[anxiolytic|anxiolysis]], and dizziness. |
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==Safety== |
==Safety== |
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Revision as of 19:57, 15 January 2019
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| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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| Excretion | urine |
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| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.002.902 |
| Chemical and physical data | |
| Formula | C10H12ClNO4 |
| Molar mass | 245.660 g/mol g·mol−1 |
| 3D model (JSmol) | |
| Melting point | 86 to 92 °C (187 to 198 °F) |
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Chlorphenesin carbamate (Maolate, Musil) is a centrally acting muscle relaxant used to treat muscle pain and spasms.[1][2] Chlorphenesin is no longer used for this purpose in most developed nations due to the availability of much safer spasmolytics such as benzodiazepines.
Other central effects include sedation, anxiolysis, and dizziness.
Safety
References
- ^ Okuyama, S; Aihara, H (1987). "Antinociceptive effect of chlorphenesin carbamate in adjuvant arthritic rats". Research communications in chemical pathology and pharmacology. 55 (2): 147–60. PMID 3823606.
- ^ Kurachi, M; Aihara, H (1984). "Effect of a muscle relaxant, chlorphenesin carbamate, on the spinal neurons of rats". Japanese journal of pharmacology. 36 (1): 7–13. doi:10.1254/jjp.36.7. PMID 6503049.