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'''Glycyrrhizol A''' is a [[prenylated]] [[pterocarpan]], a derivative of [[isoflavonoid]]s. It is a compound isolated from the root of the Chinese [[Licorice]] plant (''[[Glycyrrhiza uralensis]]'').
'''Glycyrrhizol A''' is a [[prenylated]] [[pterocarpan]] and an [[isoflavonoid]] derivative. It is a compound isolated from the root of the [[Glycyrrhiza uralensis|Chinese licorice plant]] (''Glycyrrhiza uralensis'').


Recent studies by scientists from [[University of California, Los Angeles|UCLA]] have suggested that these compounds have [[antibacterial]] properties.<ref>{{cite journal | vauthors= He J, Chen L, Shi W, ((Lu Q-Y)) | title=Antibacterial Compounds from ''Glycyrrhiza uralensis'' | journal=[[Journal of Natural Products]] | volume=69| issue=1 | year=2006 | pages=121–124 | id= | doi=10.1021/np058069d | pmid= 16441081}}</ref> The strongest antibacterial activity was observed against ''[[Streptococcus mutans]]'', an organism known to cause tooth decay in humans.
It may has ''[[in vitro]]'' [[antibacterial]] properties.<ref name = He>{{cite journal | vauthors= He J, Chen L, Shi W, ((Lu Q-Y)) | title=Antibacterial Compounds from ''Glycyrrhiza uralensis'' | journal= Journal of Natural Products | volume=69| issue=1 | year=2006 | pages=121–124 | id= | doi=10.1021/np058069d | pmid= 16441081}}</ref> In one study, the strongest antibacterial activity was observed against ''[[Streptococcus mutans]]'', an organism known to cause tooth decay in humans.<ref name = He/>


==References==
==References==
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{{Natural-phenol-stub}}
{{aromatic-stub}}

Revision as of 20:21, 22 January 2019

Glycyrrhizol A
Names
IUPAC name
1-Methoxy-2,8-bis-(3-methyl-but-2-enyl)-6H-[1]benzofuro[3,2-c]chromene-3,9-diol
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
  • InChI=1S/C26H28O5/c1-14(2)6-8-16-10-18-19-13-30-23-12-21(28)17(9-7-15(3)4)25(29-5)24(23)26(19)31-22(18)11-20(16)27/h6-7,10-12,27-28H,8-9,13H2,1-5H3 checkY
    Key: CBPFOSMNDISZLV-UHFFFAOYSA-N checkY
  • InChI=1/C26H28O5/c1-14(2)6-8-16-10-18-19-13-30-23-12-21(28)17(9-7-15(3)4)25(29-5)24(23)26(19)31-22(18)11-20(16)27/h6-7,10-12,27-28H,8-9,13H2,1-5H3
    Key: CBPFOSMNDISZLV-UHFFFAOYAJ
  • o2c1c(cc(c(O)c1)C\C=C(/C)C)c3c2c4c(OC)c(c(O)cc4OC3)C\C=C(/C)C
Properties
C26H28O5
Molar mass 420.50 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Glycyrrhizol A is a prenylated pterocarpan and an isoflavonoid derivative. It is a compound isolated from the root of the Chinese licorice plant (Glycyrrhiza uralensis).

It may has in vitro antibacterial properties.[1] In one study, the strongest antibacterial activity was observed against Streptococcus mutans, an organism known to cause tooth decay in humans.[1]

References

  1. ^ a b He J, Chen L, Shi W, Lu Q-Y (2006). "Antibacterial Compounds from Glycyrrhiza uralensis". Journal of Natural Products. 69 (1): 121–124. doi:10.1021/np058069d. PMID 16441081.


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