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m Alter: template type, journal. Add: year, doi, pages, issue, volume, journal, author pars. 1-8. Removed accessdate with no specified URL. Removed parameters. Formatted dashes. | You can use this bot yourself. Report bugs here. | User-activated.
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==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Jackson DG |title=The lymphatics revisited: new perspectives from the hyaluronan receptor LYVE-1 |journal=Trends Cardiovasc. Med. |volume=13 |issue= 1 |pages= 1–7 |year= 2003 |pmid= 12554094 |doi=10.1016/S1050-1738(02)00189-5 }}
*{{cite journal | author=Jackson DG |title=The lymphatics revisited: new perspectives from the hyaluronan receptor LYVE-1 |journal=Trends Cardiovasc. Med. |volume=13 |issue= 1 |pages= 1–7 |year= 2003 |pmid= 12554094 |doi=10.1016/S1050-1738(02)00189-5 }}
*{{cite journal | author=Banerji S |title=LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan |journal=J. Cell Biol. |volume=144 |issue= 4 |pages= 789–801 |year= 1999 |pmid= 10037799 |doi=10.1083/jcb.144.4.789 | pmc=2132933 |name-list-format=vanc | author2=Ni J | author3=Wang SX | display-authors=3 | last4=Clasper | first4=S | last5=Su | first5=J | last6=Tammi | first6=R | last7=Jones | first7=M | last8=Jackson | first8=DG }}
*{{cite journal | author=Banerji S |title=LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan |journal=J. Cell Biol. |volume=144 |issue= 4 |pages= 789–801 |year= 1999 |pmid= 10037799 |doi=10.1083/jcb.144.4.789 | pmc=2132933 |name-list-format=vanc | author2=Ni J | author3=Wang SX | display-authors=3 | last4=Clasper | first4=S | last5=Su | first5=J | last6=Tammi | first6=R | last7=Jones | first7=M | last8=Jackson | first8=DG }}
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*{{cite journal | author=Gu B |title=Expression of lymphatic vascular endothelial hyaluronan receptor-1 (LYVE-1) in the human placenta |journal=Lymphatic Research and Biology |volume=4 |issue= 1 |pages= 11–17 |year= 2007 |pmid= 16569201 |doi= 10.1089/lrb.2006.4.11 |name-list-format=vanc | author2=Alexander JS | author3=Gu Y | display-authors=3 | last4=Zhang | first4=Yanping | last5=Lewis | first5=David F. | last6=Wang | first6=Yuping | pmc=3072054 }}
*{{cite journal | author=Gu B |title=Expression of lymphatic vascular endothelial hyaluronan receptor-1 (LYVE-1) in the human placenta |journal=Lymphatic Research and Biology |volume=4 |issue= 1 |pages= 11–17 |year= 2007 |pmid= 16569201 |doi= 10.1089/lrb.2006.4.11 |name-list-format=vanc | author2=Alexander JS | author3=Gu Y | display-authors=3 | last4=Zhang | first4=Yanping | last5=Lewis | first5=David F. | last6=Wang | first6=Yuping | pmc=3072054 }}
*{{cite journal | author=Llovet JM |title=A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis |journal=Gastroenterology |volume=131 |issue= 6 |pages= 1758–1767 |year= 2007 |pmid= 17087938 |doi= 10.1053/j.gastro.2006.09.014 |name-list-format=vanc | author2=Chen Y | author3=Wurmbach E | display-authors=3 | last4=Roayaie | first4=Sasan | last5=Fiel | first5=M. Isabel | last6=Schwartz | first6=Myron | last7=Thung | first7=Swan N. | last8=Khitrov | first8=Gregory | last9=Zhang | first9=Weijia }}
*{{cite journal | author=Llovet JM |title=A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis |journal=Gastroenterology |volume=131 |issue= 6 |pages= 1758–1767 |year= 2007 |pmid= 17087938 |doi= 10.1053/j.gastro.2006.09.014 |name-list-format=vanc | author2=Chen Y | author3=Wurmbach E | display-authors=3 | last4=Roayaie | first4=Sasan | last5=Fiel | first5=M. Isabel | last6=Schwartz | first6=Myron | last7=Thung | first7=Swan N. | last8=Khitrov | first8=Gregory | last9=Zhang | first9=Weijia }}
}}
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{{refend}}


Revision as of 22:33, 20 March 2019

The lymphatic endothelium is a specialised form of epithelium, distinct from but similar to vascular endothelium. A lymph capillary endothelial cell is distinct from other endothelial cells in that collagen fibers are directly attached to its plasma membrane.

Although lymphatics were first described by Hippocrates in 400BC and rediscovered as "milky veins in the gut of a well fed dog" in the 17th century by Gasparo Aselli, they were ignored for centuries until in 1937 Howard Florey showed that lymphatics enlarge in inflammation. At this stage vascular and lymphatic endothelia were seen to be morphologically distinct and lymphatic vessels considered less important. Later it was discovered that VEGF-R3 and VEGF-C/VEGF-D were the key growth factors controlling lymphatic endothelial proliferation. Markers of lymphatic endolthelium were not discovered until relatively recently. These being LYVE-1 (Jackson et al.,1999)[1] and podoplanin (Kerjaschki,1999).[2]

See also

Endothelium

References

  1. ^ Banerji, Suneale; Ni, Jian; Wang, Shu-Xia; Clasper, Steven; Su, Jeffrey; Tammi, Raija; Jones, Margaret; Jackson, David G. (1999). "J.Cell Biol: LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan 1". The Journal of Cell Biology. 144 (4): 789–801. doi:10.1083/jcb.144.4.789.
  2. ^ "Am. J. Pathol: Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic andothelium 2".

Further reading


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