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{{Infobox scientist
{{Infobox scientist
| name = Douglass Turnbull
| name = Douglass Turnbull
|honorific_suffix=[[FMedSci]], [[Fellow of the Royal Society|FRS]]
|honorific_suffix={{post-nominals|country=GBR|FRS|FMedSci|size=100}}
|alma_mater=[[Newcastle University]]
|alma_mater=[[Newcastle University]]
|workplaces={{hlist|[[Wellcome Trust]] Centre for Mitochondrial Research |[[Newcastle University]]}}
|workplaces={{hlist|[[Wellcome Trust]] Centre for Mitochondrial Research |[[Newcastle University]]}}
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| doctoral_student =
| doctoral_student =
| website = {{URL|http://www.newcastle-mitochondria.com/portfolio/professor-doug-turnbull}}
| website = {{URL|http://www.newcastle-mitochondria.com/portfolio/professor-doug-turnbull}}
}}'''Sir Douglass Matthew Turnbull''' [[FMedSci]], [[Fellow of the Royal Society|FRS]] is [[Professor]] of [[Neurology]] at [[Newcastle University]], an Honorary Consultant Neurologist at [[Newcastle upon Tyne Hospitals NHS Foundation Trust]]<ref name=nhs>{{cite web|archiveurl=https://web.archive.org/web/20150625022435/http://www.newcastle-hospitals.org.uk/staff-profiles/12244.aspx|archivedate=2015-06-25|url=http://www.newcastle-hospitals.org.uk/staff-profiles/12244.aspx|website=newcastle-hospitals.org.uk|title=Turnbull, Professor Douglass M}}</ref> and a director of the [[Wellcome Trust]] Centre for [[Mitochondrion|Mitochondrial Research]].<ref name=mito>{{cite web|url=http://www.newcastle-mitochondria.com/portfolio/professor-doug-turnbull/|title=Professor Doug Turnbull: Personal Biography|website=newcastle-mitochondria.com|location=[[Newcastle upon Tyne]]|archiveurl=https://web.archive.org/web/20160331051532/http://www.newcastle-mitochondria.com/portfolio/professor-doug-turnbull/|archivedate=2016-03-31}}</ref><ref name=CravenTuppen2010>{{cite journal|last1=Craven|first1=Lyndsey|last2=Tuppen|first2=Helen A.|last3=Greggains|first3=Gareth D.|last4=Harbottle|first4=Stephen J.|last5=Murphy|first5=Julie L.|last6=Cree|first6=Lynsey M.|last7=Murdoch|first7=Alison P.|last8=Chinnery|first8=Patrick F.|last9=Taylor|first9=Robert W.|last10=Lightowlers|first10=Robert N.|last11=Herbert|first11=Mary|last12=Turnbull|first12=Douglass M.|title=Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease|journal=Nature|volume=465|issue=7294|year=2010|pages=82–85|pmid=20393463|pmc=2875160|doi=10.1038/nature08958}} {{open access}}</ref><ref>{{YouTube|id=Sr7Jnr9qn44|title=Healing broken batteries: The Wellcome Trust Centre for Mitochondrial Research}}, [[Wellcome Trust]], London</ref><ref>{{cite web|url=http://www.thejournal.co.uk/north-east-analysis/analysis-news/newcastle-university-medical-pioneer-doug-9164327|website=thejournal.co.uk|title=Newcastle University medical pioneer Doug Turnbull discusses his game-changing research|publisher=[[The Journal (newspaper)|The Journal]]|location=Newcastle|author=Graeme Whitfield|year=2015}}</ref>
}}'''Sir Douglass Matthew Turnbull''' {{post-nominals|country=GBR|FRS|FMedSci}} is [[Professor]] of [[Neurology]] at [[Newcastle University]], an Honorary Consultant Neurologist at [[Newcastle upon Tyne Hospitals NHS Foundation Trust]]<ref name=nhs>{{cite web|archiveurl=https://web.archive.org/web/20150625022435/http://www.newcastle-hospitals.org.uk/staff-profiles/12244.aspx|archivedate=2015-06-25|url=http://www.newcastle-hospitals.org.uk/staff-profiles/12244.aspx|website=newcastle-hospitals.org.uk|title=Turnbull, Professor Douglass M}}</ref> and a director of the [[Wellcome Trust]] Centre for [[Mitochondrion|Mitochondrial Research]].<ref name=mito>{{cite web|url=http://www.newcastle-mitochondria.com/portfolio/professor-doug-turnbull/|title=Professor Doug Turnbull: Personal Biography|website=newcastle-mitochondria.com|location=[[Newcastle upon Tyne]]|archiveurl=https://web.archive.org/web/20160331051532/http://www.newcastle-mitochondria.com/portfolio/professor-doug-turnbull/|archivedate=2016-03-31}}</ref><ref name=CravenTuppen2010>{{cite journal|last1=Craven|first1=Lyndsey|last2=Tuppen|first2=Helen A.|last3=Greggains|first3=Gareth D.|last4=Harbottle|first4=Stephen J.|last5=Murphy|first5=Julie L.|last6=Cree|first6=Lynsey M.|last7=Murdoch|first7=Alison P.|last8=Chinnery|first8=Patrick F.|last9=Taylor|first9=Robert W.|last10=Lightowlers|first10=Robert N.|last11=Herbert|first11=Mary|last12=Turnbull|first12=Douglass M.|title=Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease|journal=Nature|volume=465|issue=7294|year=2010|pages=82–85|pmid=20393463|pmc=2875160|doi=10.1038/nature08958}} {{open access}}</ref><ref>{{YouTube|id=Sr7Jnr9qn44|title=Healing broken batteries: The Wellcome Trust Centre for Mitochondrial Research}}, [[Wellcome Trust]], London</ref><ref>{{cite web|url=http://www.thejournal.co.uk/north-east-analysis/analysis-news/newcastle-university-medical-pioneer-doug-9164327|website=thejournal.co.uk|title=Newcastle University medical pioneer Doug Turnbull discusses his game-changing research|publisher=[[The Journal (newspaper)|The Journal]]|location=Newcastle|author=Graeme Whitfield|year=2015}}</ref>


==Education==
==Education==
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==References==
==References==
{{reflist|35em}}
{{reflist}}
{{FRS 2019}}

{{Authority control}}
{{Authority control}}


Revision as of 22:04, 18 April 2019

For other people called Doug Turnbull, see Douglas Turnbull (disambiguation).
Douglass Turnbull
FRS FMedSci
Alma materNewcastle University
Awards
Scientific career
Fields
Institutions
ThesisMitochondrial cytopathies: clinical and experimental studies (1983)
Websitewww.newcastle-mitochondria.com/portfolio/professor-doug-turnbull

Sir Douglass Matthew Turnbull FRS FMedSci is Professor of Neurology at Newcastle University, an Honorary Consultant Neurologist at Newcastle upon Tyne Hospitals NHS Foundation Trust[1] and a director of the Wellcome Trust Centre for Mitochondrial Research.[2][3][4][5]

Education

Turnbull was educated at Newcastle University, where he was awarded a Bachelor of Medicine, Bachelor of Surgery and qualifying as a junior doctor.[when?][2] He was subsequently awarded a PhD for research investigating Mitochondrial cytopathies.[6]

Research

Turnbull's research investigates techniques for improving the lives of patients with mitochondrial disease.[7] As of 2016 he has supervised 35 successful PhD students to completion and is currently supervising 10 PhD students in progress.[2] His most highly cited research[8] has been published in world leading peer reviewed scientific journals such as Nature,[3] Nature Genetics,[9][10] Nature Reviews Genetics,[11] the American Journal of Human Genetics,[12] and the Journal of Clinical Investigation.[13]

His research has been funded by the Wellcome Trust, the Biotechnology and Biological Sciences Research Council (BBSRC) and the Medical Research Council (MRC).[14]

Awards and honours

Turnbull delivered the Goulstonian Lectures in 1992 and was awarded the Jean Hunter Prize in 2003, both by the Royal College of Physicians.[2] He was elected a Fellow of the Academy of Medical Sciences in 2004.[15]

Turnbull was knighted in the 2016 Birthday Honours.[16] According to the BBC, his knighthood was awarded for "creating a groundbreaking IVF technique which prevents disabling genetic disorders from being passed on to future generations".[17] This technique uses mitochondrial donation, also known as "three-person babies".[18][19]

References

  1. ^ "Turnbull, Professor Douglass M". newcastle-hospitals.org.uk. Archived from the original on 2015-06-25.
  2. ^ a b c d "Professor Doug Turnbull: Personal Biography". newcastle-mitochondria.com. Newcastle upon Tyne. Archived from the original on 2016-03-31.
  3. ^ a b Craven, Lyndsey; Tuppen, Helen A.; Greggains, Gareth D.; Harbottle, Stephen J.; Murphy, Julie L.; Cree, Lynsey M.; Murdoch, Alison P.; Chinnery, Patrick F.; Taylor, Robert W.; Lightowlers, Robert N.; Herbert, Mary; Turnbull, Douglass M. (2010). "Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease". Nature. 465 (7294): 82–85. doi:10.1038/nature08958. PMC 2875160. PMID 20393463. Open access icon
  4. ^ Healing broken batteries: The Wellcome Trust Centre for Mitochondrial Research on YouTube, Wellcome Trust, London
  5. ^ Graeme Whitfield (2015). "Newcastle University medical pioneer Doug Turnbull discusses his game-changing research". thejournal.co.uk. Newcastle: The Journal.
  6. ^ Turnbull, Douglass Matthew (1983). Mitochondrial cytopathies: clinical and experimental studies (PhD thesis). Newcastle upon Tyne University. OCLC 11274373.
  7. ^ Lightowlers, Robert N.; Chinnery, Patrick F.; Turnbull, Douglass M.; Howell, Neil (1997). "Mammalian mitochondrial genetics: heredity, heteroplasmy and disease". Trends in Genetics. 13 (11): 450–455. doi:10.1016/S0168-9525(97)01266-3.
  8. ^ Douglass Turnbull's publications indexed by the Scopus bibliographic database. (subscription required)
  9. ^ Turnbull, Douglass M.; Andrews, Richard M.; Kubacka, Iwona; Chinnery, Patrick F.; Lightowlers, Robert N.; Howell, Neil (1999). "Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA". Nature Genetics. 23 (2): 147. doi:10.1038/13779. PMID 10508508.
  10. ^ Bender, Andreas; Krishnan, Kim J; Morris, Christopher M; Taylor, Geoffrey A; Reeve, Amy K; Perry, Robert H; Jaros, Evelyn; Hersheson, Joshua S; Betts, Joanne; Klopstock, Thomas; Taylor, Robert W; Turnbull, Douglass M (2006). "High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease". Nature Genetics. 38 (5): 515–517. doi:10.1038/ng1769. PMID 16604074.
  11. ^ Taylor, Robert W.; Turnbull, Doug M. (2005). "Mitochondrial DNA mutations in human disease". Nature Reviews Genetics. 6 (5): 389–402. doi:10.1038/nrg1606. PMC 1762815. PMID 15861210.
  12. ^ Herrnstadt, Corinna; Elson, Joanna L.; Fahy, Eoin; Preston, Gwen; Turnbull, Douglass M.; Anderson, Christen; Ghosh, Soumitra S.; Olefsky, Jerrold M.; Beal, M. Flint; Davis, Robert E.; Howell, Neil (2002). "Reduced-Median-Network Analysis of Complete Mitochondrial DNA Coding-Region Sequences for the Major African, Asian, and European Haplogroups". The American Journal of Human Genetics. 70 (5): 1152–1171. doi:10.1086/339933. PMC 447592. PMID 11938495. Open access icon
  13. ^ Taylor, Robert W.; Barron, Martin J.; Borthwick, Gillian M.; Gospel, Amy; Chinnery, Patrick F.; Samuels, David C.; Taylor, Geoffrey A.; Plusa, Stefan M.; Needham, Stephanie J.; Greaves, Laura C.; Kirkwood, Thomas B.L.; Turnbull, Douglass M. (2003). "Mitochondrial DNA mutations in human colonic crypt stem cells". Journal of Clinical Investigation. 112 (9): 1351–1360. doi:10.1172/JCI19435. PMC 228466. PMID 14597761. Open access icon
  14. ^ "UK Government grants awarded to Doug Turnbull". rcuk.ac.uk. Swindon: Research Councils UK. Archived from the original on 2016-06-16.
  15. ^ "Professor Doug Turnbull FMedSci". acmedsci.ac.uk. London: Academy of Medical Sciences. Archived from the original on 2016-06-16.
  16. ^ "No. 61608". The London Gazette (Supplement). 2016-06-11. p. B2.
  17. ^ Anon (2016). "Birthday honours: Mitochondrial disease doctor recognised". bbc.co.uk. London: BBC News.
  18. ^ Mark Henderson (2015). "Three-person embryos: how the mitochondrial donation battle was won. Prof Doug Turnbull successfully communicated difficult and controversial research with scientific accuracy, but in simple terms". guardian.com. London: The Guardian. Archived from the original on 2016-02-05.
  19. ^ James Gallagher (2015). "Three-person babies - not three-parent babies". bbc.co.uk. London: BBC News. Archived from the original on 2016-03-02.
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