Aminophylline: Difference between revisions

Aminophylline
	File:Aminophylline.png
Clinical data
Routes of; administration	oral, i.v.
ATC code	R03DA05 (WHO) ;
Legal status
Legal status	UK: P (Pharmacy medicines);
Pharmacokinetic data
Protein binding	60%
Elimination half-life	7-9 hours
Identifiers
	IUPAC name 1,3-dimethyl-7H-purine-2,6-dione; ethane-1,2-diamine;
CAS Number	317-34-0;
PubChem CID	9433;
DrugBank	APRD00329;
CompTox Dashboard (EPA)	DTXSID40883359 ;
ECHA InfoCard	100.005.696
Chemical and physical data
Formula	C16H24N10O4
Molar mass	420.427 g/mol g·mol−1

Browse history interactively

← Previous edit Next edit →

Content deleted Content added

VisualWikitext

Inline

Revision as of 02:00, 3 December 2006

Aminophylline is a drug combination that contains theophylline and ethylenediamine in 2:1 ratio.

Properties

It is more soluble in water than theophylline. White or slightly yellowish granules or powder, having a slight ammoniacal odor and a bitter taste. Upon exposure to air, it gradually loses ethylenediamine and absorbs carbon dioxide with the liberation of free theophylline. Its solutions are alkaline to litmus. One g dissolves in 25 mL of water to give a clear solution; 1 g dissolved in 5 mL of water crystallizes upon standing, but redissolves when a small amount of ethylenediamine is added. Insoluble in alcohol and in ether.

Mechanism of action

Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of bronchial asthma.

Brand names

Phyllocontin
Truphylline

External links

Template:ChemicalSources

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

@@ Line 26: / Line 26: @@
 ==Properties==
-It is more [[soluble]] in water than theophylline. yay. White or slightly yellowish granules or powder, having a slight ammoniacal odor and a bitter taste. Upon exposure to air, it gradually loses ethylenediamine and absorbs [[carbon dioxide]] with the liberation of free theophylline. Its solutions are alkaline to litmus. One g dissolves in 25 mL of water to give a clear solution; 1 g dissolved in 5 mL of water crystallizes upon standing, but redissolves when a small amount of ethylenediamine is added. Insoluble in alcohol and in ether.
+It is more [[soluble]] in water than theophylline. White or slightly yellowish granules or powder, having a slight ammoniacal odor and a bitter taste. Upon exposure to air, it gradually loses ethylenediamine and absorbs [[carbon dioxide]] with the liberation of free theophylline. Its solutions are alkaline to litmus. One g dissolves in 25 mL of water to give a clear solution; 1 g dissolved in 5 mL of water crystallizes upon standing, but redissolves when a small amount of ethylenediamine is added. Insoluble in alcohol and in ether.
 ==Mechanism of action==