Jump to content

Elisabeth Bik: Difference between revisions

From Wikipedia, the free encyclopedia
Browse history interactively
← Previous editNext edit →
Content deleted Content added
VisualWikitext
TjeerdB (talk | contribs)
381 edits
Moved up the section with external links which includes the link to her Twitter account
TjeerdB (talk | contribs)
381 edits
m Converted to standard Twitter template
Line 42: Line 42:
==External links==
==External links==
{{Scholia}}
{{Scholia}}
* Twitter: [https://twitter.com/MicrobiomDigest @MicrobiomDigest]
* {{Twitter | id= MicrobiomDigest }}
* [https://microbiomedigest.com/ Microbiome Digest] blog
* [https://microbiomedigest.com/ Microbiome Digest] blog
* [https://scholar.google.com/citations?user=Jo9LMfoAAAAJ&hl=en&oi=sra Google Scholar]
* [https://scholar.google.com/citations?user=Jo9LMfoAAAAJ&hl=en&oi=sra Google Scholar]

Revision as of 08:39, 3 December 2019

Elisabeth Bik
Born1966
Alma materUtrecht University
Scientific career
InstitutionsStanford University
uBiome
Thesis Cholera: vaccine development and evolution of epidemic Vibrio cholerae strains[1]

Elisabeth Margaretha Harbers-Bik (born 1966) is a microbiologist and scientific integrity consultant. Bik has gained widespread recognition for detecting photo manipulation in scientific publications.[2] Bik is the founder of Microbiome Digest,[3] a blog with daily updates on microbiome research, and the Science Integrity Digest blog.[4][5]

Early life and education

Bik was born in the Netherlands. She attended Utrecht University majoring in biology, and continued there for her doctorate. Her dissertation was about developing vaccines for new classes of Vibrio cholerae involved in cholera epidemics across India and Bangladesh.[1][6][7][8] Her doctorate and postdoctoral studies were conducted at the molecular microbiology department in the National Institute of Health and the Environment in Bilthoven.[9]

Career

Public sector

After receiving her Ph.D., Bik worked for the Netherlands National Institute for Public Health and the Environment and St. Antonius Hospital in Nieuwegein, where she organized the development of new molecular techniques for identifying infectious agents.[10][11]

Academia

In 2001, Bik moved to California to work at Stanford University in the laboratory of David Relman, where her work focused on human microbiomes, previously unidentified species in them, and their diversity across individuals.[12][13] Her work explored other mucosal microbiomes, confirming that the human oral microbiota contains distinct genera from the gut microbiota.[14]

While at Stanford, Bik worked on an Office of Naval Research project to study the microbiome of dolphins and sea lions in San Diego. She found that their microbiome was distinct from other mammals, and influenced by the sea they lived in.[15]

Private sector

In 2016 Bik left Stanford to work for uBiome, a biotech company involved in the sequencing of human microbiomes, before leaving the company in 2018 to work full-time on analyzing scientific papers for image duplication and other malpractices.[8]

Science integrity

In 2014 she had started the blog Microbiome Digest, where she provided easy-to-understand commentaries on recent scientific papers.[16] The blog soon became a success, and Bik enlisted help from her colleagues on Twitter to manage the content.[16] She is also an active contributor to Retraction Watch and PubPeer, highlighting scientific papers that present falsified, duplicated, and questionable data, such as in western blot images.[17][18]

Together with Arturo Cassadevall and Ferric Fang, Bik published an mBio paper investigating the prevalence of these questionable practices within published scientific papers, where they found nearly 400 papers with intentional figure manipulation (i.e. about 800 duplicate images).[19] She estimates half of these were created with the intention to mislead. Bik is active on the social media micro-blogging platform, Twitter, where she posts potentially duplicated figures for her more than 40,000 Twitter followers to investigate. Her investigations have exposed significant levels of scientific misconduct in several journals.[8] Also in 2018, Bik was featured on the pop science podcast "Everything Hertz."[20]

In 2019 Bik announced via Twitter, that she was taking a year off paid work to investigate scientific misconduct,[16][21][22] the subject on which she coauthored a preregistered test suggesting that "academic culture, peer control, cash-based publication incentives and national misconduct policies," but not pressure to publish, may affect scientific integrity, with nationality being a stronger predictor than individual attributes.[23] Her analysis of 960 recent papers published in Molecular and Cellular Biology found that 6.1% contained inappropriately duplicated images, about 10% of which were retracted, and lead to a pilot image screening program at the journal identifying problems with 14.5% of subsequent submissions.[24]

See also

Scholia has a profile for Elisabeth Bik (Q42775804).

References

  1. ^ a b Bik, Elisabeth M (1996). Cholera: vaccine development and evolution of epidemic Vibrio cholerae strains (Dissertation). Utrecht University. ISBN 90-90091-73-4.
  2. ^ "The Last Word On Nothing | The Fraud Finder: A conversation with Elisabeth Bik". www.lastwordonnothing.com. Retrieved 2019-09-07.
  3. ^ "Microbiome Digest". MicrobiomeDigest.com. Retrieved 2019-09-07.
  4. ^ "Science Integrity Digest". ScienceIntegrityDigest.com. Retrieved 2019-11-24.
  5. ^ "Maddox Prize 2019". senseaboutscience.org. Sense about Science. Retrieved 26 November 2019.
  6. ^ Bik, Elisabeth M.; Mooi, Frits R. (1997-04-01). "The evolution of epidemic Vibrio cholerae strains". Trends in Microbiology. 5 (4): 161–165. doi:10.1016/S0966-842X(96)10086-X. ISSN 0966-842X. PMID 9141191.
  7. ^ Mooi, F. R.; Gouw, R. D.; Bunschoten, A. E.; Bik, E. M. (1995-01-01). "Genesis of the novel epidemic Vibrio cholerae O139 strain: evidence for horizontal transfer of genes involved in polysaccharide synthesis". The EMBO Journal. 14 (2): 209–216. doi:10.1002/j.1460-2075.1995.tb06993.x. ISSN 1460-2075.
  8. ^ a b c "Eye for Manipulation: A Profile of Elisabeth Bik". The Scientist Magazine®. Retrieved 2019-11-22.
  9. ^ Bik, Elisabeth. "Elisabeth Bik - Consultant - Harbers Bik LLC". www.linkedin.com. LinkedIn. Retrieved 29 November 2019.
  10. ^ "Elisabeth Bik". Microbiome Digest - Bik's Picks. 2016-04-28. Retrieved 2019-09-07.
  11. ^ "Profile - Elisabeth Bik". peerj.com. Retrieved 2019-09-07.
  12. ^ Relman, David A.; Nelson, Karen E.; Gill, Steven R.; Sargent, Michael; Dethlefsen, Les; Purdom, Elizabeth; Bernstein, Charles N.; Bik, Elisabeth M.; Eckburg, Paul B. (2005-06-10). "Diversity of the Human Intestinal Microbial Flora". Science. 308 (5728): 1635–1638. doi:10.1126/science.1110591. ISSN 0036-8075. PMID 15831718.
  13. ^ Relman, David A.; Blaser, Martin J.; Perez-Perez, Guillermo; Francois, Fritz; Purdom, Elizabeth A.; Nelson, Karen E.; Gill, Steven R.; Eckburg, Paul B.; Bik, Elisabeth M. (2006-01-17). "Molecular analysis of the bacterial microbiota in the human stomach". Proceedings of the National Academy of Sciences. 103 (3): 732–737. doi:10.1073/pnas.0506655103. ISSN 0027-8424. PMID 16407106.
  14. ^ Relman, David A.; Fraser-Liggett, Claire M.; Gill, Steven R.; Nelson, Karen E.; Emmanuel F. Mongodin; Emerson, Joanne; Loomer, Peter; Armitage, Gary C.; Long, Clara Davis (August 2010). "Bacterial diversity in the oral cavity of 10 healthy individuals". The ISME Journal. 4 (8): 962–974. doi:10.1038/ismej.2010.30. ISSN 1751-7370.
  15. ^ Bik, Elisabeth M.; Costello, Elizabeth K.; Switzer, Alexandra D.; Callahan, Benjamin J.; Holmes, Susan P.; Wells, Randall S.; Carlin, Kevin P.; Jensen, Eric D.; Venn-Watson, Stephanie; Relman, David A. (2016-02-03). "Marine mammals harbor unique microbiotas shaped by and yet distinct from the sea". Nature Communications. 7 (1): 1–13. doi:10.1038/ncomms10516. ISSN 2041-1723.
  16. ^ a b c "I have found about 2,000 problematic papers, says Dr. Elisabeth Bik". Editage Insights. 2019-08-08. Retrieved 2019-11-22.
  17. ^ Oransky, Author Ivan (2019-05-07). "Meet Elisabeth Bik, who finds problematic images in scientific papers for free". Retraction Watch. Retrieved 2019-09-07. {{cite web}}: |first= has generic name (help)
  18. ^ "PubPeer - Search publications and join the conversation". pubpeer.com. Retrieved 2019-09-07.
  19. ^ Fang, Ferric C.; Casadevall, Arturo; Bik, Elisabeth M. (2016-07-06). "The Prevalence of Inappropriate Image Duplication in Biomedical Research Publications". mBio. 7 (3): e00809–16. doi:10.1128/mBio.00809-16. ISSN 2150-7511. PMID 27273827.
  20. ^ "Everything Hertz - Elisabeth Bik". everythinghertz.com. Retrieved 2019-09-07.
  21. ^ @MicrobiomDigest (April 26, 2019). "I am taking a year off from paid work to focus more on my science misconduct volunteer work. Science needs more help to detect image duplication, plagiarism, fabricated results, and predatory publishers" (Tweet) – via Twitter.
  22. ^ "About the Participants". FotoFocus Cincinnati. Retrieved 2019-11-22.
  23. ^ Fanelli, Daniele; Costas, Rodrigo; Fang, Ferric C.; Casadevall, Arturo; Bik, Elisabeth M. (1 June 2019). "Testing Hypotheses on Risk Factors for Scientific Misconduct via Matched-Control Analysis of Papers Containing Problematic Image Duplications". Science and Engineering Ethics. 25 (3): 771–789. doi:10.1007/s11948-018-0023-7. ISSN 1471-5546. Retrieved 25 November 2019.
  24. ^ Bik, Elisabeth M.; Fang, Ferric C.; Kullas, Amy L.; Davis, Roger J.; Casadevall, Arturo (15 October 2018). "Analysis and Correction of Inappropriate Image Duplication: the Molecular and Cellular Biology Experience". Molecular and Cellular Biology. 38 (20). doi:10.1128/MCB.00309-18. ISSN 0270-7306. Retrieved 25 November 2019.
  25. ^ "r3hso.pdf (8MB)" (PDF). web.archive.org. 2015-01-06. Retrieved 2019-11-25.{{cite web}}: CS1 maint: url-status (link)
  26. ^ "Corrigendum: Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis | Nature". www.nature.com. Retrieved 2019-11-25.
  27. ^ Bik, Elisabeth (2015-10-28). ""lanes 1 & 5 ..and lanes 6 & 10 appear to be duplicated. It is unclear how this happened"". Twitter. Retrieved 2019-11-25.{{cite web}}: CS1 maint: url-status (link)
Retrieved from "https://en.wikipedia.org/enwiki/w/index.php?title=Elisabeth_Bik&oldid=929043165"