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== Jack L. Feldman is an American neuroscientist and professor at the University of California, Los Angeles ([[University of California, Los Angeles|UCLA]]). He discovered and named the [[pre-Bötzinger complex]]<ref>{{Cite journal|last=Smith|first=J. C.|last2=Ellenberger|first2=H. H.|last3=Ballanyi|first3=K.|last4=Richter|first4=D. W.|last5=Feldman|first5=J. L.|date=1991-11-01|title=Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals|url=https://www.ncbi.nlm.nih.gov/pubmed/1683005|journal=Science (New York, N.Y.)|volume=254|issue=5032|pages=726–729|doi=10.1126/science.1683005|issn=0036-8075|pmc=3209964|pmid=1683005}}</ref>, an area in the brain stem that is responsible for controlling breathing. He was the recipient of the Hodgkin Huxley Katz Prize in 2016. ==
== '''Jack L. Feldman''' is an American neuroscientist and professor at the University of California, Los Angeles ([[University of California, Los Angeles|UCLA]]). He discovered and named the [[pre-Bötzinger complex]]<ref name=":1">{{Cite journal|last=Smith|first=J. C.|last2=Ellenberger|first2=H. H.|last3=Ballanyi|first3=K.|last4=Richter|first4=D. W.|last5=Feldman|first5=J. L.|date=1991-11-01|title=Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals|url=https://www.ncbi.nlm.nih.gov/pubmed/1683005|journal=Science (New York, N.Y.)|volume=254|issue=5032|pages=726–729|doi=10.1126/science.1683005|issn=0036-8075|pmc=3209964|pmid=1683005}}</ref>, an area in the brain stem that is responsible for controlling breathing. He was the recipient of the Hodgkin Huxley Katz Prize in 2016. ==


== Early Life ==
== Early Life ==
Dr. Feldman received his Bachelor's degree in physics from the Polytechnic Institute of NY in 1968, and a PhD in physics from the University of Chicago. His PhD focused breathing and respiratory networks from a theoretical perspective.<ref name=":0">{{Citation|last=Grillner|first=Sten|title=Chapter 13 - On walking, chewing, and breathing—A tribute to Serge, Jim, and Jack|date=2011-01-01|url=http://www.sciencedirect.com/science/article/pii/B9780444538253000188|work=Progress in Brain Research|volume=188|pages=199–211|editor-last=Gossard|editor-first=Jean Pierre|series=Breathe, Walk and Chew: The Neural Challenge: Part II|publisher=Elsevier|access-date=2020-01-19|editor2-last=Dubuc|editor2-first=Réjean|editor3-last=Kolta|editor3-first=Arlette}}</ref> He went on to perform experimental neuroscience as a postdoc in Paris with Dr. Gauthier and a second postdoc with Dr. Mort Cohen in New York. In 1978, he got his first academic appointment as assistant professor at Northwestern in Chicago, where he went through the ranks to full professor. In 1986, he moved to UCLA, where he is Distinguished Professor of Neurobiology.<ref name=":0" />
Dr. Feldman received his Bachelor's degree in physics from the Polytechnic Institute of NY in 1968, and a PhD in physics from the University of Chicago. His PhD focused breathing and respiratory networks from a theoretical perspective.<ref name=":0">{{Citation|last=Grillner|first=Sten|title=Chapter 13 - On walking, chewing, and breathing—A tribute to Serge, Jim, and Jack|date=2011-01-01|url=http://www.sciencedirect.com/science/article/pii/B9780444538253000188|work=Progress in Brain Research|volume=188|pages=199–211|editor-last=Gossard|editor-first=Jean Pierre|series=Breathe, Walk and Chew: The Neural Challenge: Part II|publisher=Elsevier|access-date=2020-01-19|editor2-last=Dubuc|editor2-first=Réjean|editor3-last=Kolta|editor3-first=Arlette}}</ref> He went on to perform experimental neuroscience as a postdoc in Paris with Dr. Gauthier and a second postdoc with Dr. Mort Cohen in New York. In 1978, he begun his first academic appointment as assistant professor at Northwestern in Chicago, where he went through the ranks to full professor. In 1986, he moved to [[University of California, Los Angeles|UCLA]], where he is Distinguished Professor of Neurobiology.<ref name=":0" />


== Research ==
== Research ==
Dr. Feldman's early research focused on locating the central pattern generator responsible for breathing in 1986 identified the [[pre-Bötzinger complex]]<ref name=":1" />. The areas was so named because it was located immediately caudal to an area he had previously named the [[Bötzinger complex|Bötzinger]] complex<ref>{{Cite book|title=Control of Ventilation. Medical physiology: a cellular and molecular approach (2nd ed., International ed.).|last=|first=|publisher=Philadelphia, PA: Saunders/Elsevier|year=2009|isbn=|location=|pages=}}</ref> in 1978 after a bottle of Bötzinger wine that was being served during dinner. In 2016, he and his collaborators identified a neuropeptide that acts in the [[pre-Bötzinger complex]] to govern sighing.<ref>{{Cite web|url=https://www.washingtonpost.com/news/speaking-of-science/wp/2016/02/08/scientists-uncover-the-brain-mechanism-that-makes-you-sigh/|title=Scientists uncover the brain mechanism that makes you sigh|last=FeltmanBioBioFreelancer|first=Rachel Feltman closeRachel|last2=Magazine|first2=Editor at Popular Science|website=Washington Post|language=en|access-date=2020-01-19}}</ref><ref>{{Citation|title=Breathing Matters|url=https://www.youtube.com/watch?v=c8WYJ3QwIpQ|language=en|access-date=2020-01-19}}</ref><ref>{{Cite journal|last=Li|first=Peng|last2=Janczewski|first2=Wiktor A.|last3=Yackle|first3=Kevin|last4=Kam|first4=Kaiwen|last5=Pagliardini|first5=Silvia|last6=Krasnow|first6=Mark A.|last7=Feldman|first7=Jack L.|date=2016-02|title=The peptidergic control circuit for sighing|url=https://www.nature.com/articles/nature16964|journal=Nature|language=en|volume=530|issue=7590|pages=293–297|doi=10.1038/nature16964|issn=1476-4687}}</ref> When this neuropeptide was introduced to the [[pre-Bötzinger complex]] animals engaged in vigorous respiratory sighing.
<br />

Dr. Feldman has published over 150 peered review papers in scientific journals.<br />


== Awards and Recognition ==
== Awards and Recognition ==

Revision as of 02:43, 19 January 2020

Jack L. Feldman is an American neuroscientist and professor at the University of California, Los Angeles (UCLA). He discovered and named the pre-Bötzinger complex[1], an area in the brain stem that is responsible for controlling breathing. He was the recipient of the Hodgkin Huxley Katz Prize in 2016.

Early Life

Dr. Feldman received his Bachelor's degree in physics from the Polytechnic Institute of NY in 1968, and a PhD in physics from the University of Chicago. His PhD focused breathing and respiratory networks from a theoretical perspective.[2] He went on to perform experimental neuroscience as a postdoc in Paris with Dr. Gauthier and a second postdoc with Dr. Mort Cohen in New York. In 1978, he begun his first academic appointment as assistant professor at Northwestern in Chicago, where he went through the ranks to full professor. In 1986, he moved to UCLA, where he is Distinguished Professor of Neurobiology.[2]

Research

Dr. Feldman's early research focused on locating the central pattern generator responsible for breathing in 1986 identified the pre-Bötzinger complex[1]. The areas was so named because it was located immediately caudal to an area he had previously named the Bötzinger complex[3] in 1978 after a bottle of Bötzinger wine that was being served during dinner. In 2016, he and his collaborators identified a neuropeptide that acts in the pre-Bötzinger complex to govern sighing.[4][5][6] When this neuropeptide was introduced to the pre-Bötzinger complex animals engaged in vigorous respiratory sighing.

Dr. Feldman has published over 150 peered review papers in scientific journals.

Awards and Recognition

  • Research Career Development Award, NIH, 1979-1984
  • Swedish Medical Research Council Visiting Scientist Fellowship, 1982-1983
  • Guest Professor, Georg-August-Universität, Göttingen, FRG, 1989
  • Christian Anfinsen Lecturer, NIH, 1989
  • MERIT Award, NIH, 1990
  • Julius H. Comroe Jr. Distinguished Lectureship, American Physiological Society, 1995
  • Geoffrey S. Dawes Lecture, Fetal and Neonatal Physiological Society, 1998
  • Society for Neuroscience Special Lecturer, 2002
  • 16th Annual HW Magoun Lecture, Brain Research Institute UCLA, 2005
  • Raymond and Beverly Sackler Distinguished Visiting Neuroscientist Lecturer, U. Toronto, 2006
  • Fellow, American Association for the Advancement of Science, 2009
  • Society for Neuroscience Special Lecturer, 2016
  • Hodgkin Huxley Katz Prize, The Physiological Society 2016
  • Outstanding Investigator Award (R35) NHLBI, NIH 2017
  • Neil S. Cherniack Lecturer, Case Western Reserve University, March 2018
  • Faculty Research Lecture, UCLA, Oct 2018


References

  1. ^ a b Smith, J. C.; Ellenberger, H. H.; Ballanyi, K.; Richter, D. W.; Feldman, J. L. (1991-11-01). "Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals". Science (New York, N.Y.). 254 (5032): 726–729. doi:10.1126/science.1683005. ISSN 0036-8075. PMC 3209964. PMID 1683005.
  2. ^ a b Grillner, Sten (2011-01-01), Gossard, Jean Pierre; Dubuc, Réjean; Kolta, Arlette (eds.), "Chapter 13 - On walking, chewing, and breathing—A tribute to Serge, Jim, and Jack", Progress in Brain Research, Breathe, Walk and Chew: The Neural Challenge: Part II, vol. 188, Elsevier, pp. 199–211, retrieved 2020-01-19
  3. ^ Control of Ventilation. Medical physiology: a cellular and molecular approach (2nd ed., International ed.). Philadelphia, PA: Saunders/Elsevier. 2009.
  4. ^ FeltmanBioBioFreelancer, Rachel Feltman closeRachel; Magazine, Editor at Popular Science. "Scientists uncover the brain mechanism that makes you sigh". Washington Post. Retrieved 2020-01-19. {{cite web}}: |first2= has generic name (help)
  5. ^ Breathing Matters, retrieved 2020-01-19
  6. ^ Li, Peng; Janczewski, Wiktor A.; Yackle, Kevin; Kam, Kaiwen; Pagliardini, Silvia; Krasnow, Mark A.; Feldman, Jack L. (2016-02). "The peptidergic control circuit for sighing". Nature. 530 (7590): 293–297. doi:10.1038/nature16964. ISSN 1476-4687. {{cite journal}}: Check date values in: |date= (help)