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In 2002, the centre filed a [[patent]] for a cyclopentabenzofuran compound that could be used together with other anti-cancer drugs.<ref>{{cite web |title=Intellectual Property Rights - Current breakthroughs |url=https://www.sbc.org.my/work-with-us/current-breakthroughs |publisher=Sarawak Biodiversity Centre |access-date=30 November 2020 |archive-url=https://web.archive.org/web/20200513225427/https://www.sbc.org.my/work-with-us/current-breakthroughs |archive-date=14 August 2020}}</ref><ref>{{cite web |last1=Meurer-Grimes |first1=BM |last2=Yu |first2=J |last3=Vairo |first3=GL |title=Therapeutic compounds and methods - US6710075B2 |url=https://patents.google.com/patent/US6710075B2/en |website=Google Patents |publisher=United States Patents |access-date=30 November 2020}}</ref>
In 2002, the centre filed a [[patent]] for a cyclopentabenzofuran compound that could be used together with other anti-cancer drugs.<ref>{{cite web |title=Intellectual Property Rights - Current breakthroughs |url=https://www.sbc.org.my/work-with-us/current-breakthroughs |publisher=Sarawak Biodiversity Centre |access-date=30 November 2020 |archive-url=https://web.archive.org/web/20200513225427/https://www.sbc.org.my/work-with-us/current-breakthroughs |archive-date=14 August 2020}}</ref><ref>{{cite web |last1=Meurer-Grimes |first1=BM |last2=Yu |first2=J |last3=Vairo |first3=GL |title=Therapeutic compounds and methods - US6710075B2 |url=https://patents.google.com/patent/US6710075B2/en |website=Google Patents |publisher=United States Patents |access-date=30 November 2020}}</ref>


In 2006, the centre started a project called "Development of Medicinal and Aromatic Oils from Sarawak's Indigenous Plants".<ref>{{cite web |title=Biodiversity Make Scents - Essential Oil Project |url=https://www.sbc.org.my/programmes/r-d-bioprospecting/28-english-categories/programmes/r-d-laboratories/29-biodiversity-make-scents |publisher=Sarawak Biodiversity Centre |access-date=11 December 2020 |archive-url=https://web.archive.org/web/20200922023745/https://www.sbc.org.my/programmes/r-d-bioprospecting/28-english-categories/programmes/r-d-laboratories/29-biodiversity-make-scents |archive-date=22 September 2020}}</ref> From indigenous traditional knowledge documentation programme, ''Litsea cubeba'' tree found at [[Bario]], [[Lawas]], and [[Padawan municipality]] was used for essential oil extraction with the support from [[Global Environment Facility]] (GEF) grant and [[United Nations Development Programme]] (UNDP). Essenial oil from the plant not only shows anti-microbial and anti-inflammatory properties, it is also able to repel insects.<ref>{{cite web |title=The LITSARA Story - Innovating Ancestral Knowledge |url=The LITSARA Story - Innovating Ancestral Knowledge |publisher=Sarawak Biodiversity Centre |access-date=11 December 2020 |archive-url=https://web.archive.org/web/20190422034402/http://www.my.undp.org/content/malaysia/en/home/ourwork/environmentandenergy/successstories/the-litsara-story-innovating-ancestral-knowledge.html |archive-date=22 April 2019}}</ref>
In 2006, the centre started a project called "Development of Medicinal and Aromatic Oils from Sarawak's Indigenous Plants".<ref>{{cite web |title=Biodiversity Make Scents - Essential Oil Project |url=https://www.sbc.org.my/programmes/r-d-bioprospecting/28-english-categories/programmes/r-d-laboratories/29-biodiversity-make-scents |publisher=Sarawak Biodiversity Centre |access-date=11 December 2020 |archive-url=https://web.archive.org/web/20200922023745/https://www.sbc.org.my/programmes/r-d-bioprospecting/28-english-categories/programmes/r-d-laboratories/29-biodiversity-make-scents |archive-date=22 September 2020}}</ref> From indigenous traditional knowledge documentation programme, ''Litsea cubeba'' tree found at [[Bario]], [[Lawas]], and [[Padawan municipality]] was used for essential oil extraction with the support from [[Global Environment Facility]] (GEF) grant and [[United Nations Development Programme]] (UNDP). Essenial oil from the plant not only shows anti-microbial and anti-inflammatory properties, it is also able to repel insects.<ref>{{cite web |title=The LITSARA Story - Innovating Ancestral Knowledge |url=https://www.my.undp.org/content/malaysia/en/home/ourwork/environmentandenergy/successstories/the-litsara-story-innovating-ancestral-knowledge.html |publisher=Sarawak Biodiversity Centre |access-date=11 December 2020 |archive-url=https://web.archive.org/web/20190422034402/http://www.my.undp.org/content/malaysia/en/home/ourwork/environmentandenergy/successstories/the-litsara-story-innovating-ancestral-knowledge.html |archive-date=22 April 2019}}</ref>


In 2016, the centre was involved in research regarding the role of [[laccase]] enzymes in cotton plant fibre development.<ref>{{cite journal |last1=Balasubramanian |first1=VK |last2=Rai |first2=KM |last3=Thu |first3=SW |last4=Hii |first4=MM |last5=Mendu |first5=V |title=Genome-wide identification of multifunctional laccase gene family in cotton (Gossypium spp.); expression and biochemical analysis during fiber development |journal=Nature Scientific Reports |date=29 September 2016 |volume=6 |issue=34309 |page=34309 |doi=10.1038/srep34309|pmid=27679939 |pmc=5041144 |bibcode=2016NatSR...634309B }}</ref>
In 2016, the centre was involved in research regarding the role of [[laccase]] enzymes in cotton plant fibre development.<ref>{{cite journal |last1=Balasubramanian |first1=VK |last2=Rai |first2=KM |last3=Thu |first3=SW |last4=Hii |first4=MM |last5=Mendu |first5=V |title=Genome-wide identification of multifunctional laccase gene family in cotton (Gossypium spp.); expression and biochemical analysis during fiber development |journal=Nature Scientific Reports |date=29 September 2016 |volume=6 |issue=34309 |page=34309 |doi=10.1038/srep34309|pmid=27679939 |pmc=5041144 |bibcode=2016NatSR...634309B }}</ref>

Revision as of 13:24, 11 December 2020

Sarawak Biodiversity Centre
Established1997
MissionTo Decode Biodiversity for the Benefit of Sarawak[1]
FocusTraditional knowledge documentation
Bioprospecting
Bioinformatics[2]
ChairJaul Samion[3]
Chief Executive OfficerYeo Tiong Chia[4]
OwnerSarawak state government
Location
KM 20, Jalan Puncak Borneo
,
Kuching
,
Sarawak
,
Malaysia
Coordinates1°23′33″N 110°19′23″E / 1.39250°N 110.32306°E / 1.39250; 110.32306
Map
Websitehttps://www.sbc.org.my/

Sarawak Biodiversity Centre is a statutory body that was set up by the government of Sarawak in 1997 for the regulation of access and collection of biological resources for research or commercial purposes. In 2004, the centre was relieved of its regulatory role and started to involve in biotechnology-based research of the biological resources in the state.

History

Sarawak Biodiversity Centre was established in 1997 following the enactment of Sarawak Biodiversity Centre Ordinance by the Sarawak state government for conservation, utilization, protection and sustainable development of biodiversity in the state. This was followed by the enactment of Sarawak Biodiversity Regulations in 1998. In December 2003, Sarawak State Legislative Assembly passed the Sarawak Biodiversity Centre (Amendment) Ordinance 2003. The state assembly also revised the Sarawak Biodiversity Regulations in 2004. Following these revisions, Sarawak Biodiversity Centre was relieved of its previous role and assumed a new role of research and development of the state biological resources and documentation of indigenous knowledge of utilising biological resources.[5]

Programmes

Traditional Knowledge Documentation Programme

This programmed existed to prevent the loss of traditional knowledge in the indigenous communities because of the knowledge pass to the next generations through oral tradition only. This programme is carried through capacity building workshops where local communities are trained with documentation techniques, growing and management of useful indigenous plants. As of 9 November 2020, a total of 6,420 plants were documented with 1,713 species of plants identified.[6]

Research and Development (Bioprospecting) Programme

This programme is supported by seven laboratories with the aim to screen for anti-cancer, anti-fungal, anti-bacterial, anti-inflammatory and anti-protease compounds from its natural products library. Besides, this programme also isolates and sequence genes from useful microbes that have medicinal and industrial applications. This programme is also developing plant tissue culture capabilities for mass propagations and genetic transformation of plants.[7]

Bioinformatics Programme

This programme aims to provide an integrated database storage and maintenance system on biological resources in the state and traditional knowledge on growing indigenous plants.[8]

Biodiversity Garden Programme

This programme collects, propagates and plants the indigenous flora of Sarawak that are used by the indigenous communities in the state. This garden provides raw plant materials for research and development. This garden is also opened for public education and tours.[9]

Awareness and Appreciation Programme

Through seminars, workshops, conferences, forums, public lectures, dialogue sessions, and exhibitions, this programme aims to disseminate accurate information on biodiversity and biotechnology to the general public, policymakers, government officials, members of the academia, researchers, industry representatives and the media.[10]

Facilities

Extraction Laboratory

At the plant preparation area, all plants will undergo washing, sorting, cutting, drying, and grinding to become ground plant samples. The samples are then extracted by using maceration solvent extraction, maceration aqueous extraction, liquid-liquid partition, and reflux extraction. The plant extracts are then deposited into the natural products library.[11]

Microbiology Laboratory

This laboratory isolates actinomycetes and fungi from plants and soil to be stored in natural products library for their antimicrobial activity testing[12]

Molecular Biology Laboratory

This laboratory aims to screen for anti-cancer and anti-inflammatory compounds from plants, actinomycetes, and fungi using molecular genetics and in vitro cell lines screening.[13]

Plant Tissue Culture Laboratory

This laboratory aims to cultivate targeted plants on a massive scale for research and development and domestication.[14]

Analytical Chemistry Laboratory

Extracts obtained from the extraction laboratory and microbiology laboratory are sent here for isolation and purification using various chromatographic techniques.[15]

Bioinformatics Data Centre

It features biological resources databases, a natural product library, and traditional knowledge databases.[16]

Product Development Laboratory

This laboratory focus on extraction of essential oils and indigenous oils, formulation of personal care products, and quality analyses of the developed products.[17]

Researches and patents

In 2002, the centre filed a patent for a cyclopentabenzofuran compound that could be used together with other anti-cancer drugs.[18][19]

In 2006, the centre started a project called "Development of Medicinal and Aromatic Oils from Sarawak's Indigenous Plants".[20] From indigenous traditional knowledge documentation programme, Litsea cubeba tree found at Bario, Lawas, and Padawan municipality was used for essential oil extraction with the support from Global Environment Facility (GEF) grant and United Nations Development Programme (UNDP). Essenial oil from the plant not only shows anti-microbial and anti-inflammatory properties, it is also able to repel insects.[21]

In 2016, the centre was involved in research regarding the role of laccase enzymes in cotton plant fibre development.[22]

References

  1. ^ "Our Mission". Sarawak Biodiversity Centre. Archived from the original on 28 October 2020. Retrieved 3 December 2020. {{cite news}}: |archive-date= / |archive-url= timestamp mismatch; 14 August 2020 suggested (help)
  2. ^ "What We Do". Sarawak Biodiversity Centre. Archived from the original on 28 October 2020. Retrieved 3 December 2020.
  3. ^ "Sarawak Biodiversity Council". Sarawak Biodiversity Centre. Archived from the original on 14 August 2020. Retrieved 29 November 2020.
  4. ^ "Management Team". Sarawak Biodiversity Centre. Archived from the original on 21 September 2020. Retrieved 29 November 2020.
  5. ^ "About SBC". Sarawak Biodiversity Centre. Archived from the original on 25 October 2020. Retrieved 29 November 2020.
  6. ^ "Traditional Knowledge documentation". Sarawak Biodiversity Centre. Archived from the original on 25 October 2020. Retrieved 3 December 2020.
  7. ^ "R&D Bioprospecting". Sarawak Biodiversity Centre. Archived from the original on 28 October 2020. Retrieved 4 December 2020. {{cite web}}: |archive-date= / |archive-url= timestamp mismatch; 14 August 2020 suggested (help)
  8. ^ "Bioinformatics". Sarawak Biodiversity Centre. Archived from the original on 28 October 2020. Retrieved 9 December 2020.
  9. ^ "Biodiversity Garden". Sarawak Biodiversity Centre. Archived from the original on 25 October 2020. Retrieved 9 December 2020.
  10. ^ "Awareness & Appreciation Programme". Sarawak Biodiversity Centre. Archived from the original on 21 September 2020. Retrieved 9 December 2020.
  11. ^ "Extraction Laboratory". Sarawak Biodiversity Centre. Archived from the original on 22 September 2020. Retrieved 10 December 2020.
  12. ^ "Microbiology Laboratory". Sarawak Biodiversity Centre. Archived from the original on 22 September 2020. Retrieved 10 December 2020.
  13. ^ "Molecular Biology Laboratory". Sarawak Biodiversity Centre. Archived from the original on 22 September 2020. Retrieved 10 December 2020.
  14. ^ "Plant Tissue Culture Laboratory". Sarawak Biodiversity Centre. Archived from the original on 25 October 2020. Retrieved 11 December 2020.
  15. ^ "Analytical Chemistry Laboratory". Sarawak Biodiversity Centre. Archived from the original on 22 September 2020. Retrieved 11 December 2020.
  16. ^ "Bioinformatics". Sarawak Biodiversity Centre. Archived from the original on 22 September 2020. Retrieved 3 December 2020.
  17. ^ "Product Development". Sarawak Biodiversity Centre. Archived from the original on 21 September 2020. Retrieved 3 December 2020.
  18. ^ "Intellectual Property Rights - Current breakthroughs". Sarawak Biodiversity Centre. Archived from the original on 14 August 2020. Retrieved 30 November 2020. {{cite web}}: |archive-date= / |archive-url= timestamp mismatch; 13 May 2020 suggested (help)
  19. ^ Meurer-Grimes, BM; Yu, J; Vairo, GL. "Therapeutic compounds and methods - US6710075B2". Google Patents. United States Patents. Retrieved 30 November 2020.
  20. ^ "Biodiversity Make Scents - Essential Oil Project". Sarawak Biodiversity Centre. Archived from the original on 22 September 2020. Retrieved 11 December 2020.
  21. ^ "The LITSARA Story - Innovating Ancestral Knowledge". Sarawak Biodiversity Centre. Archived from the original on 22 April 2019. Retrieved 11 December 2020.
  22. ^ Balasubramanian, VK; Rai, KM; Thu, SW; Hii, MM; Mendu, V (29 September 2016). "Genome-wide identification of multifunctional laccase gene family in cotton (Gossypium spp.); expression and biochemical analysis during fiber development". Nature Scientific Reports. 6 (34309): 34309. Bibcode:2016NatSR...634309B. doi:10.1038/srep34309. PMC 5041144. PMID 27679939.

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