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Cowdry bodies

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Liver, high power, demonstrating Cowdry bodies within hepatocytes. Lakhan and Harle Journal of Medical Case Reports 2008.[1]

Cowdry bodies are eosinophilic nuclear inclusions composed of nucleic acid and protein seen in cells infected with Herpes simplex virus or Varicella-zoster virus.

There are two types of intranuclear Cowdry bodies:

  • Type A (as seen in herpes infection) [2]
  • Type B (as seen in infection with poliovirus), though it may seem that this is an antiquated and perhaps illusory type. [3]

References

  1. ^ Lakhan SE, Harle L (2008). "Fatal fulminant herpes simplex hepatitis secondary to tongue piercing in an immunocompetent adult: a case report". J Med Case Reports. 2: 356. doi:10.1186/1752-1947-2-356. PMC 2603042.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  2. ^ "Herpes Group (Cytomegalovirus, Herpes simplex, Varicella/Zoster, Epstein-Barr)". Retrieved 2009-01-02.
  3. ^ http://stanford.wellsphere.com/brain-health-article/whiter-the-illusory-cowdry-b-inclusion-of-polio/491368