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Feinstein Institutes for Medical Research

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The Feinstein Institute for Medical Research
Established1999
Location, ,
Websitehttp://www.nslij.com/

Science at the Feinstein Institute


Established in 1999, The Feinstein Institute for Medical Research is a research institute on the grounds of the North Shore-LIJ Health System in Manhasset, NY. Over 200 Feinstein investigators are involved with the study of immunity, autoimmune diseases, cancer, neurodegenerative diseases and neuropsychiatric conditions. The institute collaborates with universites worldwide and has an on-going training agreement with the Karolinska Institute in Stockholm. Scientists collaborate with clinicians throughout the North Shore-LIJ Health System (including North Shore University Hospital and Long Island Jewish Medical Center to identify the underlying mechanisms of disease. Patients can participate in clinical trials related to the use of experimental drugs that are in various stages of clinical and preclinical testing for cancer, cardiac disease, sepsis, shock, trauma, arthritis, and other inflammatory conditions. The institute is known for its work in autoimmune and inflammatory diseases as well as neurological conditions like Parkinson's and Alzheimer's. The volume of National Institutes of Health-funded, patient-oriented research programs in the Feinstein Institute is significant: Over 80% of their research projects come under the category of patient-oriented research, and nearly 65% of these projects are supported by federal grants.

The Feinstein manages the Elmezzi Graduate School of Molecular Medicine, a degree granting body chartered by the State University of New York, which confers medical school graduates, pursuing a career in research, with the PhD degree in molecular medicine. The Feinstein publishes Molecular Medicine, an international, peer-reviewed journal that reports on fast-breaking developments in molecular medicine.

The Feinstein's major assets include: The NIH-funded General Clinical Research Center that offers state-of-the-art facilities for designing, implementing and conducting clinical research studies in a central location; the NIH-funded Early-Phase Schizophrenia Center focuses on the development of the best treatments for schizophrenia; a Laboratory of Medicinal Biochemistry dedicated to the Feinstein’s drug discovery efforts and develops and streamlines preclinical testing methods; the Laboratory of Medicinal Chemistry that develops experimental drugs based upon the mechanisms of diseases discovered by Feinstein investigators.

History

In 1985, North Shore University Hospital constructed, on its Manhasset campus, a research building to foster the growth of clinical and translational science centers. Clinical research at North Shore University Hospital underwent expansion at this time, highlighted by the addition of new technology, including one of the earliest MRI scanners in New York State, and a PET scanner and cyclotron facility that was first not only in New York State but was one of the first on the east coast. Long Island Jewish Medical Center (LIJ), which later merged with North Shore University Hospital, established a functioning Research Committee in 1956, funded by clinical practice income, to support pilot research projects by junior faculty. The first National Institutes of Health (NIH) research grants to LIJ faculty were also awarded in 1956. The Feinstein Institute has a large portfolio of research, including studies on cancer, leukemia, lymphoma, Parkinson's disease, Alzheimer’s disease, psychiatric disorders, rheumatoid arthritis, lupus, sepsis, inflammatory bowel disease, diabetes, human genetics, neuroimmunology, and medicinal chemistry. Feinstein researchers are developing new drugs and drug targets, and annually enrolling some 10,000 subjects into clinical research programs.

Facility details

The Feinstein Institute for Medical Research

  • >55 laboratories
  • 300 research and clinical scientists
  • 10 physician/scientists enrolled in The Elmezzi Graduate School for Molecular Medicine

Areas of basic interdisciplinary research

  • biochemistry, structural biology and chemistry
  • genetics
  • molecular, cell and developmental biology
  • immunology, virology and microbiology
  • medical sciences and human genetics
  • neuroscience


Affiliations

References