JWH-307
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| Formula | C26H24FNO |
| Molar mass | 385.472 g/mol g·mol−1 |
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JWH-307 is an analgesic drug used in scientific research, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It is somewhat selective for the CB2 subtype, with a Ki of 7.7nM at CB1 vs 3.3nM at CB2.[1] It was discovered by, and named after, Dr. John W. Huffman. JWH-307 was detected as an ingredient in synthetic cannabis smoking blends in 2012, initially in Germany.[2][3]
See also
References
- ^ Huffman JW, Padgett LW, Isherwood ML, Wiley JL, Martin BR. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB1 and CB2 receptors. Bioorganic & Medicinal Chemistry Letters 2006; 16:5432-5435.
- ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 22748479, please use {{cite journal}} with
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|pmid=22791249instead.
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