Pokeweed mitogen
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Pokeweed mitogen is a mitogen derived from Phytolacca americana. It functions as a lectin.
Clinical Significance
Pokeweed mitogen has the ability to play a role for the immune system. It can test for immunodeficiency by inducing B-cell proliferation and test for abnormal counts. [1] It can also induce proliferation of cells that target tumors, which is useful for the treatment of cancer. [2]
References
- ^ Bekeredjian-Ding, Isabelle; Foermer, Sandra; Kirschning, Carsten J.; Parcina, Marijo; Heeg, Klaus (2012-01-04). "Poke Weed Mitogen Requires Toll-Like Receptor Ligands for Proliferative Activity in Human and Murine B Lymphocytes". PLOS ONE. 7 (1): e29806. doi:10.1371/journal.pone.0029806. ISSN 1932-6203. PMC 3251602. PMID 22238657.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ Numa, K.; Tani, T.; Kodama, M. (1990). "Trial of anticancer immunotherapy with immobilized pokeweed mitogen: immunotherapy by extracorporeal circulation". Cancer immunology, immunotherapy: CII. 32 (2): 125–130. doi:10.1007/BF01754209. ISSN 0340-7004. PMID 2289204.
External links
- Pokeweed+mitogens at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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