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User:Kelsidc/Computational epigenetics

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Computational epigenetics[1] [2][unreliable source?] uses statistical methods and mathematical modelling in epigeneticresearch. Due to the recent explosion of epigenome datasets, computational methods play an increasing role in all areas of epigenetic research.

Definition

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Research in computational epigenetics comprises the development and application of bioinformatics methods for solving epigenetic questions, as well as computational data analysis and theoretical modeling in the context of epigenetics. This includes modelling of the effects of histone and DNA CpG island methylation.

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  1. ^ Bock, C; Lengauer T (2008). "Computational epigenetics". Bioinformatics. 24 (1): 1–10. doi:10.1093/bioinformatics/btm546. PMID 18024971.
  2. ^ Lim, S J; Tan T W; Tong J C (2010). "Computational epigenetics: the new scientific paradigm" (PDF). Bioinformation. 4 (7): 331–337. doi:10.6026/97320630004331. PMC 2957762. PMID 20978607.

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