The following are the seeded players, based on WTA rankings as of 25 April 2022. Rankings and points before are as of 9 May 2022.[2]
Because Rome is a non-mandatory event, but players must count, if played, at least two non-mandatory WTA 1000 tournaments on their rankings, points will be adjusted the following way:
Players who have points from the 2021 tournament counting towards their ranking, will get those points replaced by:
The points from the 2022 tournament, if they have less than two non-mandatory WTA 1000 events or 16 total tournaments counting towards their ranking.
The points from the 2022 tournament or their 17th best result, whichever is higher, if they have at least two non-mandatory WTA 1000 events counting towards their ranking.
Players who don't have points from the 2021 tournament counting towards their ranking, will have their ranking adjusted the following way:
The points from the 2022 tournament will be added to the players counting less than 16 tournaments towards their ranking.
The points from the 2022 tournament will replace the 16th best result of the players counting less than two non-mandatory WTA 1000 towards their ranking.
The points from the 2022 tournament, if higher, will replace the points from the worse non-mandatory WTA 1000 event or the 16th best result, whichever is lower, of the players counting two non-mandatory WTA 1000 events towards their ranking.
The points from the 2022 tournament, if higher, will replace the 16th best result of the players counting more than two non-mandatory WTA 1000 events towards their ranking.