Solute carrier organic anion transporter family member 4A1

SLCO4A1
Identifiers
Aliases	SLCO4A1, OATP-E, OATP1, OATP4A1, OATPE, OATPRP1, POAT, SLC21A12, solute carrier organic anion transporter family member 4A1
External IDs	OMIM: 612436; MGI: 1351866; HomoloGene: 9482; GeneCards: SLCO4A1; OMA:SLCO4A1 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	62,685,785 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	180,116,660 bp
RNA expression pattern
	Top expressed in
	right lung; ; upper lobe of left lung; ; skin of leg; ; skin of abdomen; ; left uterine tube; ; ectocervix; ; tibial nerve; ; gastric mucosa; ; apex of heart; ; gastrocnemius muscle;
	Top expressed in
	neural layer of retina; ; Paneth cell; ; retinal pigment epithelium; ; primary oocyte; ; epithelium of lens; ; trigeminal ganglion; ; conjunctival fornix; ; zygote; ; epithelium of stomach; ; secondary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transporter activity; sodium-independent organic anion transmembrane transporter activity; thyroid hormone transmembrane transporter activity;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane;
Biological process	ion transport; sodium-independent organic anion transport; thyroid hormone transport; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	28231
	108115
	ENSG00000101187
	ENSMUSG00000038963
	Q96BD0
	Q8K078
	NM_016354
	NM_148933; NM_001355218
	NP_057438
	NP_683735; NP_001342147
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier organic anion transporter family member 4A1 is a protein that in humans is encoded by the SLCO4A1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000101187 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038963 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tamai I, Nezu J, Uchino H, Sai Y, Oku A, Shimane M, Tsuji A (Jul 2000). "Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family". Biochem Biophys Res Commun. 273 (1): 251–60. doi:10.1006/bbrc.2000.2922. PMID 10873595.
^ "Entrez Gene: SLCO4A1 solute carrier organic anion transporter family, member 4A1".

Fujiwara K, Adachi H, Nishio T, et al. (2001). "Identification of thyroid hormone transporters in humans: different molecules are involved in a tissue-specific manner". Endocrinology. 142 (5): 2005–12. doi:10.1210/endo.142.5.8115. PMID 11316767.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Pizzagalli F, Varga Z, Huber RD, et al. (2003). "Identification of steroid sulfate transport processes in the human mammary gland". J. Clin. Endocrinol. Metab. 88 (8): 3902–12. doi:10.1210/jc.2003-030174. PMID 12915686.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wang P, Wang JJ, Xiao Y, et al. (2005). "Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface". J. Biol. Chem. 280 (34): 30143–9. doi:10.1074/jbc.M503969200. PMID 15994332.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000101187 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038963 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10873595-5] Tamai I, Nezu J, Uchino H, Sai Y, Oku A, Shimane M, Tsuji A (Jul 2000). "Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family". Biochem Biophys Res Commun. 273 (1): 251–60. doi:10.1006/bbrc.2000.2922. PMID 10873595.

[entrez-6] "Entrez Gene: SLCO4A1 solute carrier organic anion transporter family, member 4A1".

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Solute carrier organic anion transporter family member 4A1

See also

References

Further reading