Jump to content

Talk:Liposome

Page contents not supported in other languages.
From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Soupvector (talk | contribs) at 20:14, 31 January 2024 (Is the liposome figure correct?: maybe not clear, but not clearly wrong?). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

unsourced list

following is unsourced; moved here per PRESERVE. Do not restore without reliable sourcing per WP:BURDEN

List of drugs

As of 2012, 13 drugs with liposomal delivery systems have been approved and five additional liposomal drugs were in clinical trials.[citation needed]

List of clinically approved liposomal drugs
Name Trade name Company Indication Liposomal Excipients
Liposomal amphotericin B Abelcet Enzon Fungal infections DMPC and DMPG
Liposomal amphotericin B Ambisome Gilead Sciences Fungal and protozoal infections HSPC, Cholesterol, DSPG
Liposomal cytarabine Depocyt Pacira (formerly SkyePharma) Malignant lymphomatous meningitis DOPC, Cholesterol, DPPG
Liposome Pro-Liposome base Chemajet Chemical and Pharmaceutical Industries Employ surface ligands for attaching to unhealthy tissue LEC. Phosphatidylcholine
Liposomal daunorubicin DaunoXome Gilead Sciences HIV-related Kaposi’s sarcoma DSPC, Cholesterol
Liposomal doxorubicin Myocet Zeneus Combination therapy with cyclophosphamide in metastatic breast cancer LIPOVA-E120, Cholesterol
Liposomal IRIV vaccine Epaxal Crucell Hepatitis A LECIVA-S70
Liposomal IRIV vaccine Inflexal V Berna Biotech Influenza LECIVA-S90
Liposomal morphine DepoDur SkyePharma, Endo Postsurgical analgesia DOPC, Cholesterol, DPPG
Liposomal verteporfin Visudyne QLT, Novartis Age-related macular degeneration, pathologic myopia, ocular histoplasmosis Egg PG, DMPC
Liposome-proteins SP-B and SP-C Curosurf Chiesi Farmaceutici, S.p.A. pulmonary surfactant for Respiratory Distress Syndrome (RDS) Leciva-S90
Liposome-PEG doxorubicin Doxil/Caelyx Ortho Biotech, Schering-Plough HIV-related Kaposi’s sarcoma, metastatic breast cancer, metastatic ovarian cancer MPEG-DSPE, HSPC, Cholesterol
Micellular estradiol Estrasorb Novavax Menopausal therapy Soybean oil, Polysorbate80
Liposomal vincristine Marqibo Spectrum Pharmaceuticals Acute Lymphoblastic Leukemia (ALL) and Melanoma Cholesterol and egg sphingomyelin
Liposome-PEG doxorubicin Lipo-Dox TTY BIOPHARM HIV-related Kaposi’s sarcoma, metastatic breast cancer, metastatic ovarian cancer, Multiple Myeloma MPEG-DSPE, DSPC, Cholesterol

--Jytdog (talk) 23:23, 28 January 2017 (UTC)[reply]

Is the liposome figure correct?

The liposome figure shown at the top of the article has lipids with only one tail for the inner layer. My understanding is that phospholipids always have two tails. If so, then this figure is misleading and should be corrected. Steven.s.andrews (talk) 18:11, 31 January 2024 (UTC)[reply]

I'm not sure I'm seeing the same thing - the tails are not well-resolved ("muddy") and so I'm not sure they're 1- or 2-tailed. Maybe others will help clarify. — soupvector (talk) 20:14, 31 January 2024 (UTC)[reply]