Talk:Liposome
Appearance
This is the talk page for discussing improvements to the Liposome article. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL |
Archives: 1Auto-archiving period: 2 months |
This article has not yet been rated on Wikipedia's content assessment scale. It is of interest to the following WikiProjects: | ||||||||||||||||||||||||||||||||||||||||||||||||||
Please add the quality rating to the {{WikiProject banner shell}} template instead of this project banner. See WP:PIQA for details.
Please add the quality rating to the {{WikiProject banner shell}} template instead of this project banner. See WP:PIQA for details.
Please add the quality rating to the {{WikiProject banner shell}} template instead of this project banner. See WP:PIQA for details.
|
unsourced list
following is unsourced; moved here per PRESERVE. Do not restore without reliable sourcing per WP:BURDEN
- List of drugs
The examples and perspective in this section may not represent a worldwide view of the subject. (January 2012) |
As of 2012, 13 drugs with liposomal delivery systems have been approved and five additional liposomal drugs were in clinical trials.[citation needed]
Name | Trade name | Company | Indication | Liposomal Excipients |
Liposomal amphotericin B | Abelcet | Enzon | Fungal infections | DMPC and DMPG |
Liposomal amphotericin B | Ambisome | Gilead Sciences | Fungal and protozoal infections | HSPC, Cholesterol, DSPG |
Liposomal cytarabine | Depocyt | Pacira (formerly SkyePharma) | Malignant lymphomatous meningitis | DOPC, Cholesterol, DPPG |
Liposome | Pro-Liposome base | Chemajet Chemical and Pharmaceutical Industries | Employ surface ligands for attaching to unhealthy tissue | LEC. Phosphatidylcholine |
Liposomal daunorubicin | DaunoXome | Gilead Sciences | HIV-related Kaposi’s sarcoma | DSPC, Cholesterol |
Liposomal doxorubicin | Myocet | Zeneus | Combination therapy with cyclophosphamide in metastatic breast cancer | LIPOVA-E120, Cholesterol |
Liposomal IRIV vaccine | Epaxal | Crucell | Hepatitis A | LECIVA-S70 |
Liposomal IRIV vaccine | Inflexal V | Berna Biotech | Influenza | LECIVA-S90 |
Liposomal morphine | DepoDur | SkyePharma, Endo | Postsurgical analgesia | DOPC, Cholesterol, DPPG |
Liposomal verteporfin | Visudyne | QLT, Novartis | Age-related macular degeneration, pathologic myopia, ocular histoplasmosis | Egg PG, DMPC |
Liposome-proteins SP-B and SP-C | Curosurf | Chiesi Farmaceutici, S.p.A. | pulmonary surfactant for Respiratory Distress Syndrome (RDS) | Leciva-S90 |
Liposome-PEG doxorubicin | Doxil/Caelyx | Ortho Biotech, Schering-Plough | HIV-related Kaposi’s sarcoma, metastatic breast cancer, metastatic ovarian cancer | MPEG-DSPE, HSPC, Cholesterol |
Micellular estradiol | Estrasorb | Novavax | Menopausal therapy | Soybean oil, Polysorbate80 |
Liposomal vincristine | Marqibo | Spectrum Pharmaceuticals | Acute Lymphoblastic Leukemia (ALL) and Melanoma | Cholesterol and egg sphingomyelin |
Liposome-PEG doxorubicin | Lipo-Dox | TTY BIOPHARM | HIV-related Kaposi’s sarcoma, metastatic breast cancer, metastatic ovarian cancer, Multiple Myeloma | MPEG-DSPE, DSPC, Cholesterol |
--Jytdog (talk) 23:23, 28 January 2017 (UTC)
Is the liposome figure correct?
The liposome figure shown at the top of the article has lipids with only one tail for the inner layer. My understanding is that phospholipids always have two tails. If so, then this figure is misleading and should be corrected. Steven.s.andrews (talk) 18:11, 31 January 2024 (UTC)
- I'm not sure I'm seeing the same thing - the tails are not well-resolved ("muddy") and so I'm not sure they're 1- or 2-tailed. Maybe others will help clarify. — soupvector (talk) 20:14, 31 January 2024 (UTC)
Categories:
- C-Class Chemistry articles
- Mid-importance Chemistry articles
- WikiProject Chemistry articles
- C-Class medicine articles
- Mid-importance medicine articles
- All WikiProject Medicine pages
- C-Class Molecular Biology articles
- Unknown-importance Molecular Biology articles
- C-Class MCB articles
- Low-importance MCB articles
- WikiProject Molecular and Cellular Biology articles
- All WikiProject Molecular Biology pages