User:Lichomsm/Early onset dementia

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Lead

Early onset dementia or young onset dementia refers to dementia with symptom onset prior to age 65. This condition is a significant public health concern as the number of individuals with early onset dementia is increasing worldwide, highlighting the importance of accurate diagnosis, management, and treatment for this disease.

Article body

Overview

Early onset dementia is a general term that describes progressive cognitive decline, particularly deficits in behavior, executive function, or language. This condition may occur due to various different causes, including degenerative, inflammatory, or infectious processes. Early-onset Alzheimer's disease, frontotemporal lobar degeneration, and vascular dementia are the most common forms of early onset dementia, with Alzheimer's disease accounting for between 30 and 40% of cases^[1]. Early onset dementia may also occur in the Lewy body dementias (dementia with Lewy bodies and Parkinson's disease dementia), multiple sclerosis, Huntington's disease, and other conditions.

Epidemiology

Recent studies estimate the prevalence of early onset dementia to be approximately 3.9 million people aged 30-64 worldwide, with an incidence of 119 per 100,000 individuals^[2].

Terminology

Age of onset

References

^ Quach, C.; Hommet, C.; Mondon, K.; Lauvin, M. A.; Cazals, X.; Cottier, J. P. (2014-04-01). "Early-onset dementias: Specific etiologies and contribution of MRI". Diagnostic and Interventional Imaging. 95 (4): 377–398. doi:10.1016/j.diii.2013.07.009. ISSN 2211-5684.
^ Hendriks, Stevie; Peetoom, Kirsten; Bakker, Christian; van der Flier, Wiesje M.; Papma, Janne M.; Koopmans, Raymond; Verhey, Frans R. J.; de Vugt, Marjolein; Köhler, Sebastian; Withall, Adrienne; Parlevliet, Juliette L.; Uysal-Bozkir, Özgül; Gibson, Roger C.; Neita, Susanne M.; Nielsen, Thomas Rune (2021-09). "Global Prevalence of Young-Onset Dementia". JAMA Neurology. 78 (9): 1–11. doi:10.1001/jamaneurol.2021.2161. ISSN 2168-6149. PMC 8290331. PMID 34279544. {{cite journal}}: Check date values in: |date= (help)

[1] Quach, C.; Hommet, C.; Mondon, K.; Lauvin, M. A.; Cazals, X.; Cottier, J. P. (2014-04-01). "Early-onset dementias: Specific etiologies and contribution of MRI". Diagnostic and Interventional Imaging. 95 (4): 377–398. doi:10.1016/j.diii.2013.07.009. ISSN 2211-5684.

[2] Hendriks, Stevie; Peetoom, Kirsten; Bakker, Christian; van der Flier, Wiesje M.; Papma, Janne M.; Koopmans, Raymond; Verhey, Frans R. J.; de Vugt, Marjolein; Köhler, Sebastian; Withall, Adrienne; Parlevliet, Juliette L.; Uysal-Bozkir, Özgül; Gibson, Roger C.; Neita, Susanne M.; Nielsen, Thomas Rune (2021-09). "Global Prevalence of Young-Onset Dementia". JAMA Neurology. 78 (9): 1–11. doi:10.1001/jamaneurol.2021.2161. ISSN 2168-6149. PMC 8290331. PMID 34279544. {{cite journal}}: Check date values in: |date= (help)

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