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Disseminated coccidioidomycosis

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Disseminated coccidioidomycosis
Other namesCoccidioidal granuloma
Characteristic skin granulomata on the forehead.
SpecialtyInfectious diseases

Disseminated coccidioidomycosis is a systemic infection with Coccidioides immitis, in which 15-20% of people develop skin lesions.[1]: 315 

History of Treatment

In 1959, "Disseminated Coccidioidomycosis Treated with Amphotericin B" was published in the New York State Journal of Medicine, documenting perhaps one of the earliest uses of the drug amphotericin B for a patient who was admitted to the U.S. Public Health Service Hospital in Seattle, Washington. Disseminated coccidioidomycosis had been lacking specific chemotherapeutic treatment until approximately three years ago when amphotericin B, a polyene antifungal antibiotic, was tried. Since then, there have been a number of reports on the beneficial clinical effect of the drug in patients with coccidioidomycosis. [2]

See also

References

  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. ^ La Barbera, M.D., Salvatore A. (October 1, 1959). "Disseminated Coccidioidomycosis Treated with Amphotericin B". New York State Journal of Medicine. 59 (19): 3644.