Disseminated coccidioidomycosis
Disseminated coccidioidomycosis | |
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Other names | Coccidioidal granuloma |
Characteristic skin granulomata on the forehead. | |
Specialty | Infectious diseases |
Disseminated coccidioidomycosis is a systemic infection with Coccidioides immitis, in which 15-20% of people develop skin lesions.[1]: 315
History of Treatment
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In 1959, "Disseminated Coccidioidomycosis Treated with Amphotericin B" was published in the New York State Journal of Medicine, documenting perhaps one of the earliest uses of the drug amphotericin B for a patient who was admitted to the U.S. Public Health Service Hospital in Seattle, Washington. Disseminated coccidioidomycosis had been lacking specific chemotherapeutic treatment until approximately three years ago when amphotericin B, a polyene antifungal antibiotic, was tried. Since then, there have been a number of reports on the beneficial clinical effect of the drug in patients with coccidioidomycosis. [2]
See also
References
- ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ^ La Barbera, M.D., Salvatore A. (October 1, 1959). "Disseminated Coccidioidomycosis Treated with Amphotericin B". New York State Journal of Medicine. 59 (19): 3644.