Disseminated coccidioidomycosis
| Disseminated coccidioidomycosis | |
|---|---|
| Other names | Coccidioidal granuloma |
 | |
| Characteristic skin granulomata on the forehead. | |
| Specialty | Infectious diseases |
Disseminated coccidioidomycosis is a systemic infection caused by Coccidioides immitis, in which 15-20% of people develop skin lesions.[1]: 315
History of Treatment
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In 1959, the New York State Journal of Medicine published the article "Disseminated Coccidioidomycosis Treated with Amphotericin B," which documented one of the earliest uses of amphotericin B in treating disseminated coccidioidomycosis. The patient was admitted to the U.S. Public Health Service Hospital in Seattle, Washington. Prior to the introduction of amphotericin B, disseminated coccidioidomycosis had no specific chemotherapeutic treatment. Amphotericin B, a polyene antifungal antibiotic, was first trialed for this condition approximately three years earlier. Since then, multiple reports have highlighted the drug's clinical effectiveness in patients with coccidioidomycosis. [2]
See also
References
- ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ^ La Barbera, M.D., Salvatore A. (October 1, 1959). "Disseminated Coccidioidomycosis Treated with Amphotericin B". New York State Journal of Medicine. 59 (19): 3644.