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Jayant B. Udgaonkar

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Jayant B. Udgaonkar
जयंत उदगांवकर
Born (1960-03-22) March 22, 1960 (age 64)
Maharashtra
EducationIIT Madras (MSc) Cornell University (PhD)
Alma materSt. Xavier's College, Mumbai (BSc)
Organization(s)National Centre for Biological Sciences, IISER Pune
Known forProtein-folding
SpouseDr. Suhasini Udgaonkar
Websitesites.google.com/acads.iiserpune.ac.in/prof-udgaonkar-lab

Jayant Bhalchandra Udgaonkar is a molecular biologist studying the processes by which a random chain of amino acids stabilises into a functional structure during or after translation. [1][2] Without any major scientific contribution, he has nevertheless established himself as a prominent protein-folding scientist amongst the local scientific community (for notable contributions in the field, see protein folding). In 2016, the Biophysical Journal published a retraction notice [3] citing evidence of manipulation via duplication, mirroring, and rescaling of identical data in one of his papers.[4]

Early Life and Education

Born on 22 March 1960 to Dr. Bhalchandra Udgaonkar, a theoretical physicist, and Dr. Suhasini Udgaonkar, a renowned historian, Dr. Jayant Udgaonkar studied Chemistry at St. Xavier's College, Mumbai (BSc, 1979) and IIT Madras (MSc, 1981), and Biochemistry at Cornell University.[2][5][6]

Protein Folding

While studying the kinetics of acetylcholine receptors in response to the binding of ACh at Stanford University, he was struck by the structural precision of protein molecules that enabled them to perform highly specialized tasks with extreme precision. Consequently, he focused his attention on the processes that make these structures possible, and what may go wrong in these highly accurate processes. In one of his earliest studies, he found that a certain hydrophobic collapse is the first stage in a typical protein folding process. His current work focuses on the formation of amyloids.[7][8]

Controversies

In a controversial speech in 2024, Dr. Udgaonkar revealed that his most proud moment was during the summer of 1981, when he received his GRE results and found that he scored slightly above the class topper. According to Dr. Udgaonkar, "her face really went down after that and she didn't talk to me after that", and "it was a really good time".[9]

"The need to be right is the sign of a vulgar mind." - Albert Camus; quote on many of Dr. Udgaonkar's papers and articles

Legacy

He is the son of noted scientist Bhalchandra Udgaonkar.[10]

Awards and Honors

Selected bibliography

  • Jayant B Udgaonkar, Robert L Baldwin (November 1990). "Early folding intermediate of ribonuclease A." Proceedings of the National Academy of Sciences. 87 (21): 8197–8201. Bibcode:1990PNAS...87.8197U. doi:10.1073/pnas.87.21.8197. PMC 54922. PMID 2236032.

References

  1. ^ "Jayant B. Udgaonkar - IISER Pune".
  2. ^ a b "Felicitation Event Honouring Prof. Jayant B. Udgaonkar at IISER Pune".
  3. ^ "Retraction Notice to: The Pathogenic A116V Mutation Enhances Ion-Selective Channel Formation by Prion Protein in Membranes" (PDF). Biophysical Society. 7 December 2021. Retrieved 24 September 2024.
  4. ^ "The Pathogenic A116V Mutation Enhances Ion-Selective Channel Formation by Prion Protein in Membranes". Biophysical Society. 26 April 2016. Retrieved 24 September 2024.
  5. ^ Phondke, Bal; Sheth, Parul R.; Naik-Satam, Suhas; Deshpande, A.P. (2007). B.M. Udgaonkar: Eminent Scientist and Educationist (PDF). Mumbai: National Center for Science Communication; Homi Bhabha Centre for Science Communication.
  6. ^ a b "Profile on NCBS" (PDF). National Centre for Biological Sciences. 2016. Retrieved 15 October 2016.
  7. ^ "Jayant Udgaonkar on Google Scholar". Author profile. Google Scholar. 2016. Retrieved 16 October 2016.
  8. ^ "Jayant Udgaonkar on ResearchGate". Author profile. 2016. Retrieved 16 October 2016.
  9. ^ "28:36 Speech during Felicitation Event".
  10. ^ Phondke, Bal; Sheth, Parul R.; Naik-Satam, Suhas; Deshpande, A.P. (2007). B.M. Udgaonkar: Eminent Scientist and Educationist (PDF). Mumbai: National Center for Science Communication; Homi Bhabha Centre for Science Communication.
  11. ^ "Rashtriya Vigyan Puraskar (RVP) - 2024 : Final List of Awardees" (PDF). awards.gov.in. CASU, Ministry of Home Affairs, Government of India. Retrieved 15 August 2024.
  12. ^ "Rashtriya Vigyan Puraskar: Chandrayaan-3 team and 32 others selected for first ever edition". The Economic Times. 7 August 2024. Retrieved 15 August 2024.
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