Sirenomelia

Sirenomelia or Mermaid Syndrome is a very rare congential deformity in which the legs are fused together, giving the appearance of a mermaid. This condition is found in approximately one out of every 70,000 live births^[1] (about as rare as conjoined twins) and is usually fatal within a day or two of birth because of complications associated with abnormal kidney and bladder development and function. It results from a failure of normal vascular supply from the lower aorta in utero. Sirenomelia is associated with maternal diabetes.^{[citation needed]}

Only a handful of patients who did not have the usual kidney and bladder complications have survived this condition, two of them being Tiffany Yorks of the United States and Milagros Cerrón of Peru. Tiffany Yorks (born 1988) underwent successful surgery to correct her rare congenital defect, in order to separate her legs. She and Milagros Cerrón (her name meaning "miracles" in Spanish) are the only two successful operations at this time. Yorks's surgeon, Mutaz Habal, worked in an advisory capacity during Cerrón's operation.

This disorder was formerly thought to be an extreme case of Caudal Regression Syndrome; however, it was reclassified to be considered a separate condition.

References

^ Kallen B, Castilla EE, Lancaster PA, Mutchinick O, Knudsen LB, Martinez-Frias ML, Mastroiacovo P, Robert E (1992). "The cyclops and the mermaid: an epidemiological study of two types of rare malformation". J Med Genet. 29 (1): 30–5. PMID 1552541.{{cite journal}}: CS1 maint: multiple names: authors list (link)

External links

KB Taori, K Mitra, NP Ghonge, RO Gandhi, T Mammen, J Sahu. Sirenomelia Sequence (Mermaid)- Report of Three Cases. Ind J Radiol Imag 2002 12:3:399-401
Birth Disorder Information Directory - contains many pointers to other references
http://www.sirenomelia.org/en/
"Peru's 'mermaid' girl doing well" at BBC News, 14 December 2005.
"'Mermaid' Girl Takes First Steps " - 26 September 2006 BBC article providing update on Milagros Cerron.

[1] Milagros Cerron.
Article in Daily Mail

Peru's 'miracle baby' walks on her own at San Francisco Chronicle, 20 April 2007

[Kallen-1] Kallen B, Castilla EE, Lancaster PA, Mutchinick O, Knudsen LB, Martinez-Frias ML, Mastroiacovo P, Robert E (1992). "The cyclops and the mermaid: an epidemiological study of two types of rare malformation". J Med Genet. 29 (1): 30–5. PMID 1552541.{{cite journal}}: CS1 maint: multiple names: authors list (link)

[1]