Talk:Quercetin

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This is on the list of IARC Carcinogens in Group 3, meaning that its carcinogenicity can't be determined in humans or that insufficient info exists on its carcinogenicity in humans. That always seemed odd to be, given how much its anticancer properties have been discussed. Does evidence exist that it is, in fact, a carcinogen? Such information should be included if it does exist and is reliable.

Quercetin has an LC50 of about 0.0001 Molar meaning to high a concentration kills normal cells. I have heard nothing about it causing cancer. I am not a formal expert in this field.

Topical Absorption using Ultrasound

The british journal said "Quercetin is a small and slightly lipophilic molecule (molecular weight=302 Da, octanol-water partition coefficient, Ko/w~1.2±0.13 (Brown et al, 1998)) and is expected to diffuse across cell membranes at a high rate."

It appears that the ultrasound doesn't increase absorption (in this case) but that something else is involved. The article suggest something about a cellular stress response. We need a source on the statement about ultrasound increasing the absorption. Unless someone convinces me otherwise, in the future I might edit this article.