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Nebulette

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nebulette
Identifiers
SymbolNEBL
NCBI gene10529
HGNC16932
OMIM605491
RefSeqNM_006393
UniProtO76041
Other data
LocusChr. 10 p12
Search for
StructuresSwiss-model
DomainsInterPro

Nebulette is an isoform of the protein nebulin. While nebulin (600-900 kDa) is expressed preferentially in skeletal muscle, nebulette (107 kDa) is expressed in cardiac muscle. Nebulette was identified in 1995 by Mocman and Wang using primary cultures of chicken embryonic cardiomyocytes by immunoprecipitations with certain anti-nebulin monoclonal antibodies.[1]

References

  1. ^ Moncman & Wang (1995). "Nebulette: a 107 kD nebulin-like protein in cardiac muscle". Cell Motil Cytoskeleton. 32 (3): 205–25. PMID 8581976.
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