MCI Screen
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The MCI Screen is a brief neuropsychological test derived from the protocol of the CERAD 10-word recall test. The test consists of three immediate recall tasks, a triadic comparison task, a judgment task, a delayed free recall task, a cued-recall task, and a rehearsed recall task. It is scored using correspondence analysis and sophisticated statistical methods that yield high accuracy for differentiating Normal cognitive function from Mild Cognitive Impairment. The methodology for scoring the MCI Screen was developed by Medical Care Corporation, a privately held California Corporation.
Technical validation
The MCI Screen was validated in a study on 471 community dwelling adults whose scores on the Clinical Dementia Rating Scale ranged from 0 (normal: N=119), 0.5 (mild cognitive impairment: N=95), to 1 (mild dementia: N=257). The MCI Screen showed overall accuracy of 98% with sensitivity of 97% for mild cognitive impairment or mild dementia, and 88% specificity for normal aging. [1]
Clinical validation
The MCI Screen is used by specialists and primary care physicians in clinical practice to identify early stage memory loss due to underlying medical conditions including Alzheimer's disease, cerebrovascular disease, and others.[2]
References
- ^ Shankle WR, Romney AK, Hara J, et al. Method to improve the detection of mild cognitive impairment. PNAS. 2005; 102(13): 4919-24..
- ^ Trenkle D, Shankle WR, Azen SP. Detecting Cognitive Impairment in Primary Care: Performance Assessment of Three Screening Instruments. Journal of Alzheimer's Disease. 2007; 11(3):323-335.