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FOSB

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FOSB
Identifiers
AliasesFOSB, AP-1, G0S3, GOS3, GOSB, FosB, ΔFosB, FosB proto-oncogene, AP-1 transcription factor subunit
External IDsOMIM: 164772; MGI: 95575; HomoloGene: 31403; GeneCards: FOSB; OMA:FOSB - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001114171
NM_006732

NM_008036
NM_001347586

RefSeq (protein)

NP_001107643
NP_006723

NP_001334515
NP_032062

Location (UCSC)Chr 19: 45.47 – 45.48 MbChr 7: 19.04 – 19.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

FBJ murine osteosarcoma viral oncogene homolog B (also known as FOSB or FosB) is a human gene.[5]

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Delta FosB

Delta FosB is a truncated splice variant of FosB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain.[6]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000125740Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003545Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: FOSB FBJ murine osteosarcoma viral oncogene homolog B".
  6. ^ Werme M, Messer C, Olson L; et al. (2002). "Delta FosB regulates wheel running". J. Neurosci. 22 (18): 8133–8. PMID 12223567. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.