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Lazarus syndrome

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Lazarus syndrome is the spontaneous return of circulation after failed attempts at resuscitation.[1] Its occurrence has been noted in medical literature at least 25 times since 1982.[2] Also called Lazarus phenomenon, it takes its name from the biblical story of Lazarus, who was said to be raised from the dead by Jesus.[3]

Occurrences of the syndrome are rare and the causes are not well understood. One theory for the phenomenon is that a chief factor (though not the only one) is the buildup of pressure in the chest as a result of cardiopulmonary resuscitation (CPR). The relaxation of pressure after resuscitation efforts have ended is thought to allow the heart to expand, triggering the heart's electrical impulses and restarting the heartbeat.[1] Other possible factors are hyperkalaemia or high doses of adrenaline.[3]


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Implications

The Lazarus Syndrome raises ethical issues for doctors, who must determine when medical death has occurred, resuscitation efforts should end, and post-mortem procedures such as autopsies and organ harvesting may take place.[1] One doctor wrote, "Perhaps it is a supreme hubris on our part to presume that we can reliably distinguish the reversible from the irreversible, or the salvageable from the nonsalvageable."[1]

Medical literature has recommended observation of a patient's vital signs for five to ten minutes after cessation of resuscitation before certifying death.[3]

See also

References

  1. ^ a b c d Ben-David M.D., Bruce (2001). "Survival After Failed Intraoperative Resuscitation: A Case of "Lazarus Syndrome"". Anesth Analg. 92: 690–692. PMID 11226103. Retrieved 2008-10-14. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  2. ^ Cite error: The named reference delaware-case was invoked but never defined (see the help page).
  3. ^ a b c Walker, A. (2001). "The Lazarus phenomenon following recreational drug use". Emerg Med J. 18: 74–75. PMID 11310473. Retrieved 2008-10-29. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)