Barker's hypothesis
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The Barker Hypothesis is named after David J. P. Barker a researcher at the University of Southampton who published the theory in 1997.[1] The theory states that reduced fetal growth is strongly associated with a number of chronic conditions later in life. Also called Thrifty phenotype. This increased susceptibility results from adaptations made by the fetus in an environment limited in its supply of nutrients. These chronic conditions include coronary heart disease, stroke, diabetes, and hypertension.
References
- ^ Barker, D.J.P. (1997). "Maternal Nutrition, Fetal Nutrition, and Disease in Later Life". Nutrition, '13', pg. 807