Hashimoto's encephalopathy
Hashimoto's Encephalopathy is a very rare condition associated with Hashimoto's Thyroiditis. Hashimoto's Encephalopathy is a neuroendocrine disorder. Thyroid antibodies in the disease are increased but do not correlate with the severity. Some of the most common symptoms of Hashimoto's Encephalopathy include: disorientation, psychosis, tremors, concentration and memory problems, jerks in the muscles and lack of coordination, headaches, partial paralysis on the right side, speech problems, seizures and coma. Sometimes, patients are mistakenly diagnosed as having had a stroke, or having Alzheimer's disease. Because most patients respond to steroids or immunosuppressant treatment, this condition is now also referred to as "steroid-responsive" encephalopathy.
Aetiology
Alpha-enolase has been identified as an autoantigen in the disease.[1]
Alternative names
- Steroid-responsive encephalopathy associated with autoimmune thyroiditis, SREAT
- Sometimes also mentioned as nonvasculitic autoimmune meningoencephalitis, NAIM
External links
- An article on Hashimoto's encephalopathy
- [1]
- Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1016/S0140-6736(03)12517-2, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with
|doi=10.1016/S0140-6736(03)12517-2instead.
References
- ^ Yoneda M, Fujii A, Ito A, Yokoyama H, Nakagawa H, Kuriyama M. High prevalence of serum autoantibodies against the amino terminal of alpha-enolase in Hashimoto's encephalopathy. J Neuroimmunol. 2007 Apr;185(1-2):195-200. Epub 2007 Mar 1. PMID 17335908