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Mean platelet volume

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Mean Platelet Volume (MPV) is a measurement of the average size of platelets found in blood and is typically included in blood tests. Since the average platelet size is larger when the body is producing increased numbers of platelets, MPV test results can be used to make inferences about platelet production in bone marrow. Abnormally low MPV values correlate primarily with thrombocytopenia when it is due to impaired production as in aplastic anemia, and it is increased, even appears as 'giant platelets', when there is increased peripheral destruction, as in immune thrombocytopenic purpua, also known as ITP, also increased in myeloproliferative disorders and Bernard-Soulier syndrome.

A typical range of platelet volumes is 9.7–12.8 fL (femtolitre), equivalent to spheres 2.65 to 2.9 µm in diameter.



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